352 related articles for article (PubMed ID: 26686752)
1. Current and Future Perspectives on the Development, Evaluation, and Application of in Silico Approaches for Predicting Toxicity.
Patlewicz G; Fitzpatrick JM
Chem Res Toxicol; 2016 Apr; 29(4):438-51. PubMed ID: 26686752
[TBL] [Abstract][Full Text] [Related]
2. The value of in silico chemistry in the safety assessment of chemicals in the consumer goods and pharmaceutical industries.
Modi S; Hughes M; Garrow A; White A
Drug Discov Today; 2012 Feb; 17(3-4):135-42. PubMed ID: 22063083
[TBL] [Abstract][Full Text] [Related]
3. Toxicology Strategies for Drug Discovery: Present and Future.
Blomme EA; Will Y
Chem Res Toxicol; 2016 Apr; 29(4):473-504. PubMed ID: 26588328
[TBL] [Abstract][Full Text] [Related]
4. Use of animals for toxicology testing is necessary to ensure patient safety in pharmaceutical development.
Mangipudy R; Burkhardt J; Kadambi VJ
Regul Toxicol Pharmacol; 2014 Nov; 70(2):439-41. PubMed ID: 25058855
[TBL] [Abstract][Full Text] [Related]
5. Integrating (Q)SAR models, expert systems and read-across approaches for the prediction of developmental toxicity.
Hewitt M; Ellison CM; Enoch SJ; Madden JC; Cronin MT
Reprod Toxicol; 2010 Aug; 30(1):147-60. PubMed ID: 20006701
[TBL] [Abstract][Full Text] [Related]
6. Novel technologies and an overall strategy to allow hazard assessment and risk prediction of chemicals, cosmetics, and drugs with animal-free methods.
Leist M; Lidbury BA; Yang C; Hayden PJ; Kelm JM; Ringeissen S; Detroyer A; Meunier JR; Rathman JF; Jackson GR; Stolper G; Hasiwa N
ALTEX; 2012; 29(4):373-88. PubMed ID: 23138508
[TBL] [Abstract][Full Text] [Related]
7. A review of the status of alternative approaches to animal testing and the development of integrated testing strategies for assessing the toxicity of chemicals under REACH--a summary of a DEFRA-funded project conducted by Liverpool John Moores University and FRAME.
Grindon C; Combes R; Cronin MT; Roberts DW; Garrod J
Altern Lab Anim; 2006 Mar; 34 Suppl 1():149-58. PubMed ID: 16555968
[TBL] [Abstract][Full Text] [Related]
8. In silico approaches to explore toxicity end points: issues and concerns for estimating human health effects.
Matthews EJ; Contrera JF
Expert Opin Drug Metab Toxicol; 2007 Feb; 3(1):125-34. PubMed ID: 17269899
[TBL] [Abstract][Full Text] [Related]
9. Toxicology Strategies for Drug Discovery - Present and Future: Introduction.
Humphreys WG; Will Y; Guengerich FP
Chem Res Toxicol; 2016 Apr; 29(4):437. PubMed ID: 27087588
[No Abstract] [Full Text] [Related]
10. The current status of exposure-driven approaches for chemical safety assessment: A cross-sector perspective.
Sewell F; Aggarwal M; Bachler G; Broadmeadow A; Gellatly N; Moore E; Robinson S; Rooseboom M; Stevens A; Terry C; Burden N
Toxicology; 2017 Aug; 389():109-117. PubMed ID: 28774667
[TBL] [Abstract][Full Text] [Related]
11. The use of computer models in pharmaceutical safety evaluation.
Boyer S
Altern Lab Anim; 2009 Nov; 37(5):467-75. PubMed ID: 20017577
[TBL] [Abstract][Full Text] [Related]
12. Non-animal methodologies within biomedical research and toxicity testing.
Knight A
ALTEX; 2008; 25(3):213-31. PubMed ID: 18841317
[TBL] [Abstract][Full Text] [Related]
13. Alternative methods to safety studies in experimental animals: role in the risk assessment of chemicals under the new European Chemicals Legislation (REACH).
Lilienblum W; Dekant W; Foth H; Gebel T; Hengstler JG; Kahl R; Kramer PJ; Schweinfurth H; Wollin KM
Arch Toxicol; 2008 Apr; 82(4):211-36. PubMed ID: 18322675
[TBL] [Abstract][Full Text] [Related]
14. Formation of mechanistic categories and local models to facilitate the prediction of toxicity.
Cronin MT; Enoch SJ; Hewitt M; Madden JC
ALTEX; 2011; 28(1):45-9. PubMed ID: 21311849
[TBL] [Abstract][Full Text] [Related]
15. A strategy for systemic toxicity assessment based on non-animal approaches: The Cosmetics Europe Long Range Science Strategy programme.
Desprez B; Dent M; Keller D; Klaric M; Ouédraogo G; Cubberley R; Duplan H; Eilstein J; Ellison C; Grégoire S; Hewitt NJ; Jacques-Jamin C; Lange D; Roe A; Rothe H; Blaauboer BJ; Schepky A; Mahony C
Toxicol In Vitro; 2018 Aug; 50():137-146. PubMed ID: 29499337
[TBL] [Abstract][Full Text] [Related]
16. Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information.
Shah I; Liu J; Judson RS; Thomas RS; Patlewicz G
Regul Toxicol Pharmacol; 2016 Aug; 79():12-24. PubMed ID: 27174420
[TBL] [Abstract][Full Text] [Related]
17. Developing alternatives to systemic toxicity testing approaches.
von Aulock S
ALTEX; 2012; 29(1):1. PubMed ID: 22408846
[No Abstract] [Full Text] [Related]
18. Implementing Toxicity Testing in the 21st Century (TT21C): Making safety decisions using toxicity pathways, and progress in a prototype risk assessment.
Adeleye Y; Andersen M; Clewell R; Davies M; Dent M; Edwards S; Fowler P; Malcomber S; Nicol B; Scott A; Scott S; Sun B; Westmoreland C; White A; Zhang Q; Carmichael PL
Toxicology; 2015 Jun; 332():102-11. PubMed ID: 24582757
[TBL] [Abstract][Full Text] [Related]
19. SEURAT: Safety Evaluation Ultimately Replacing Animal Testing--recommendations for future research in the field of predictive toxicology.
Daston G; Knight DJ; Schwarz M; Gocht T; Thomas RS; Mahony C; Whelan M
Arch Toxicol; 2015 Jan; 89(1):15-23. PubMed ID: 25433540
[TBL] [Abstract][Full Text] [Related]
20. Non-testing approaches under REACH--help or hindrance? Perspectives from a practitioner within industry.
Patlewicz G; Chen MW; Bellin CA
SAR QSAR Environ Res; 2011 Mar; 22(1-2):67-88. PubMed ID: 21391142
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]