BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

435 related articles for article (PubMed ID: 26700805)

  • 1. SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination.
    Zhao DY; Gish G; Braunschweig U; Li Y; Ni Z; Schmitges FW; Zhong G; Liu K; Li W; Moffat J; Vedadi M; Min J; Pawson TJ; Blencowe BJ; Greenblatt JF
    Nature; 2016 Jan; 529(7584):48-53. PubMed ID: 26700805
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ZPR1 prevents R-loop accumulation, upregulates SMN2 expression and rescues spinal muscular atrophy.
    Kannan A; Jiang X; He L; Ahmad S; Gangwani L
    Brain; 2020 Jan; 143(1):69-93. PubMed ID: 31828288
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation.
    Richard P; Feng S; Tsai YL; Li W; Rinchetti P; Muhith U; Irizarry-Cole J; Stolz K; Sanz LA; Hartono S; Hoque M; Tadesse S; Seitz H; Lotti F; Hirano M; Chédin F; Tian B; Manley JL
    Autophagy; 2021 Aug; 17(8):1889-1906. PubMed ID: 32686621
    [TBL] [Abstract][Full Text] [Related]  

  • 4. HuD interacts with survival motor neuron protein and can rescue spinal muscular atrophy-like neuronal defects.
    Hubers L; Valderrama-Carvajal H; Laframboise J; Timbers J; Sanchez G; Côté J
    Hum Mol Genet; 2011 Feb; 20(3):553-79. PubMed ID: 21088113
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II.
    Liu Y; Iqbal A; Li W; Ni Z; Wang Y; Ramprasad J; Abraham KJ; Zhang M; Zhao DY; Qin S; Loppnau P; Jiang H; Guo X; Brown PJ; Zhen X; Xu G; Mekhail K; Ji X; Bedford MT; Greenblatt JF; Min J
    Nat Commun; 2022 Sep; 13(1):5453. PubMed ID: 36114190
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Arginine methylation of the DDX5 helicase RGG/RG motif by PRMT5 regulates resolution of RNA:DNA hybrids.
    Mersaoui SY; Yu Z; Coulombe Y; Karam M; Busatto FF; Masson JY; Richard S
    EMBO J; 2019 Aug; 38(15):e100986. PubMed ID: 31267554
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SUMOylated Senataxin functions in genome stability, RNA degradation, and stress granule disassembly, and is linked with inherited ataxia and motor neuron disease.
    Bennett CL; La Spada AR
    Mol Genet Genomic Med; 2021 Dec; 9(12):e1745. PubMed ID: 34263556
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Ewing's sarcoma protein interacts with the Tudor domain of the survival motor neuron protein.
    Young PJ; Francis JW; Lince D; Coon K; Androphy EJ; Lorson CL
    Brain Res Mol Brain Res; 2003 Nov; 119(1):37-49. PubMed ID: 14597228
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Senataxin, defective in the neurodegenerative disorder ataxia with oculomotor apraxia 2, lies at the interface of transcription and the DNA damage response.
    Yüce Ö; West SC
    Mol Cell Biol; 2013 Jan; 33(2):406-17. PubMed ID: 23149945
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The C-terminal domain of RNA polymerase II is modified by site-specific methylation.
    Sims RJ; Rojas LA; Beck DB; Bonasio R; Schüller R; Drury WJ; Eick D; Reinberg D
    Science; 2011 Apr; 332(6025):99-103. PubMed ID: 21454787
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mutation in senataxin alters the mechanism of R-loop resolution in amyotrophic lateral sclerosis 4.
    Kannan A; Cuartas J; Gangwani P; Branzei D; Gangwani L
    Brain; 2022 Sep; 145(9):3072-3094. PubMed ID: 35045161
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functional role for senataxin, defective in ataxia oculomotor apraxia type 2, in transcriptional regulation.
    Suraweera A; Lim Y; Woods R; Birrell GW; Nasim T; Becherel OJ; Lavin MF
    Hum Mol Genet; 2009 Sep; 18(18):3384-96. PubMed ID: 19515850
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A novel function for the survival motoneuron protein as a translational regulator.
    Sanchez G; Dury AY; Murray LM; Biondi O; Tadesse H; El Fatimy R; Kothary R; Charbonnier F; Khandjian EW; Côté J
    Hum Mol Genet; 2013 Feb; 22(4):668-84. PubMed ID: 23136128
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Termination of non-coding transcription in yeast relies on both an RNA Pol II CTD interaction domain and a CTD-mimicking region in Sen1.
    Han Z; Jasnovidova O; Haidara N; Tudek A; Kubicek K; Libri D; Stefl R; Porrua O
    EMBO J; 2020 Apr; 39(7):e101548. PubMed ID: 32107786
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy.
    Chitiprolu M; Jagow C; Tremblay V; Bondy-Chorney E; Paris G; Savard A; Palidwor G; Barry FA; Zinman L; Keith J; Rogaeva E; Robertson J; Lavallée-Adam M; Woulfe J; Couture JF; Côté J; Gibbings D
    Nat Commun; 2018 Jul; 9(1):2794. PubMed ID: 30022074
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Genome-wide R-loop analysis defines unique roles for DDX5, XRN2, and PRMT5 in DNA/RNA hybrid resolution.
    Villarreal OD; Mersaoui SY; Yu Z; Masson JY; Richard S
    Life Sci Alliance; 2020 Oct; 3(10):. PubMed ID: 32747416
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PRMT9 is a type II methyltransferase that methylates the splicing factor SAP145.
    Yang Y; Hadjikyriacou A; Xia Z; Gayatri S; Kim D; Zurita-Lopez C; Kelly R; Guo A; Li W; Clarke SG; Bedford MT
    Nat Commun; 2015 Mar; 6():6428. PubMed ID: 25737013
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural basis for dimethylarginine recognition by the Tudor domains of human SMN and SPF30 proteins.
    Tripsianes K; Madl T; Machyna M; Fessas D; Englbrecht C; Fischer U; Neugebauer KM; Sattler M
    Nat Struct Mol Biol; 2011 Nov; 18(12):1414-20. PubMed ID: 22101937
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Combined deficiency of Senataxin and DNA-PKcs causes DNA damage accumulation and neurodegeneration in spinal muscular atrophy.
    Kannan A; Bhatia K; Branzei D; Gangwani L
    Nucleic Acids Res; 2018 Sep; 46(16):8326-8346. PubMed ID: 30010942
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Senataxin: Genome Guardian at the Interface of Transcription and Neurodegeneration.
    Groh M; Albulescu LO; Cristini A; Gromak N
    J Mol Biol; 2017 Oct; 429(21):3181-3195. PubMed ID: 27771483
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.