BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 26701387)

  • 21. Marine-Derived 2-Aminoimidazolone Alkaloids. Leucettamine B-Related Polyandrocarpamines Inhibit Mammalian and Protozoan DYRK & CLK Kinases.
    Loaëc N; Attanasio E; Villiers B; Durieu E; Tahtouh T; Cam M; Davis RA; Alencar A; Roué M; Bourguet-Kondracki ML; Proksch P; Limanton E; Guiheneuf S; Carreaux F; Bazureau JP; Klautau M; Meijer L
    Mar Drugs; 2017 Oct; 15(10):. PubMed ID: 29039762
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B.
    Tahtouh T; Elkins JM; Filippakopoulos P; Soundararajan M; Burgy G; Durieu E; Cochet C; Schmid RS; Lo DC; Delhommel F; Oberholzer AE; Pearl LH; Carreaux F; Bazureau JP; Knapp S; Meijer L
    J Med Chem; 2012 Nov; 55(21):9312-30. PubMed ID: 22998443
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Temperature does matter-an additional dimension in kinase inhibitor development.
    Strauch M; Heyd F
    FEBS J; 2021 May; 288(10):3148-3153. PubMed ID: 32946682
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Differential effect of CLK SR Kinases on HIV-1 gene expression: potential novel targets for therapy.
    Wong R; Balachandran A; Mao AY; Dobson W; Gray-Owen S; Cochrane A
    Retrovirology; 2011 Jun; 8():47. PubMed ID: 21682887
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability.
    Iwai K; Yaguchi M; Nishimura K; Yamamoto Y; Tamura T; Nakata D; Dairiki R; Kawakita Y; Mizojiri R; Ito Y; Asano M; Maezaki H; Nakayama Y; Kaishima M; Hayashi K; Teratani M; Miyakawa S; Iwatani M; Miyamoto M; Klein MG; Lane W; Snell G; Tjhen R; He X; Pulukuri S; Nomura T
    EMBO Mol Med; 2018 Jun; 10(6):. PubMed ID: 29769258
    [TBL] [Abstract][Full Text] [Related]  

  • 26. New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis.
    Tazarki H; Zeinyeh W; Esvan YJ; Knapp S; Chatterjee D; Schröder M; Joerger AC; Khiari J; Josselin B; Baratte B; Bach S; Ruchaud S; Anizon F; Giraud F; Moreau P
    Eur J Med Chem; 2019 Mar; 166():304-317. PubMed ID: 30731399
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors.
    Saldivia M; Fang E; Ma X; Myburgh E; Carnielli JBT; Bower-Lepts C; Brown E; Ritchie R; Lakshminarayana SB; Chen YL; Patra D; Ornelas E; Koh HXY; Williams SL; Supek F; Paape D; McCulloch R; Kaiser M; Barrett MP; Jiricek J; Diagana TT; Mottram JC; Rao SPS
    Nat Microbiol; 2020 Oct; 5(10):1207-1216. PubMed ID: 32661312
    [TBL] [Abstract][Full Text] [Related]  

  • 28. 5-Methoxybenzothiophene-2-Carboxamides as Inhibitors of Clk1/4: Optimization of Selectivity and Cellular Potency.
    ElHady AK; El-Gamil DS; Chen PJ; Hwang TL; Abadi AH; Abdel-Halim M; Engel M
    Molecules; 2021 Feb; 26(4):. PubMed ID: 33668683
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Selective inhibition of the kinase DYRK1A by targeting its folding process.
    Kii I; Sumida Y; Goto T; Sonamoto R; Okuno Y; Yoshida S; Kato-Sumida T; Koike Y; Abe M; Nonaka Y; Ikura T; Ito N; Shibuya H; Hosoya T; Hagiwara M
    Nat Commun; 2016 Apr; 7():11391. PubMed ID: 27102360
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Computer-aided identification of novel protein targets of bisphenol A.
    Montes-Grajales D; Olivero-Verbel J
    Toxicol Lett; 2013 Oct; 222(3):312-20. PubMed ID: 23973438
    [TBL] [Abstract][Full Text] [Related]  

  • 31. cDNA cloning and characterization of rat Clk3, a LAMMER kinase predominately expressed in testis.
    Becker W; Kentrup H; Heukelbach J; Joost HG
    Biochim Biophys Acta; 1996 Jun; 1312(1):63-7. PubMed ID: 8679717
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing.
    Debdab M; Carreaux F; Renault S; Soundararajan M; Fedorov O; Filippakopoulos P; Lozach O; Babault L; Tahtouh T; Baratte B; Ogawa Y; Hagiwara M; Eisenreich A; Rauch U; Knapp S; Meijer L; Bazureau JP
    J Med Chem; 2011 Jun; 54(12):4172-86. PubMed ID: 21615147
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Development of Selective Clk1 and -4 Inhibitors for Cellular Depletion of Cancer-Relevant Proteins.
    ElHady AK; Abdel-Halim M; Abadi AH; Engel M
    J Med Chem; 2017 Jul; 60(13):5377-5391. PubMed ID: 28561591
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Potent and selective small molecule inhibitors of specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk).
    Rosenthal AS; Tanega C; Shen M; Mott BT; Bougie JM; Nguyen DT; Misteli T; Auld DS; Maloney DJ; Thomas CJ
    Bioorg Med Chem Lett; 2011 May; 21(10):3152-8. PubMed ID: 21450467
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Synergistic apoptotic effects in cancer cells by the combination of CLK and Bcl-2 family inhibitors.
    Murai A; Ebara S; Sasaki S; Ohashi T; Miyazaki T; Nomura T; Araki S
    PLoS One; 2020; 15(10):e0240718. PubMed ID: 33064779
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Structure-based design and synthesis of potent benzothiazole inhibitors of interleukin-2 inducible T cell kinase (ITK).
    MacKinnon CH; Lau K; Burch JD; Chen Y; Dines J; Ding X; Eigenbrot C; Heifetz A; Jaochico A; Johnson A; Kraemer J; Kruger S; Krülle TM; Liimatta M; Ly J; Maghames R; Montalbetti CA; Ortwine DF; Pérez-Fuertes Y; Shia S; Stein DB; Trani G; Vaidya DG; Wang X; Bromidge SM; Wu LC; Pei Z
    Bioorg Med Chem Lett; 2013 Dec; 23(23):6331-5. PubMed ID: 24138940
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution.
    Colwill K; Pawson T; Andrews B; Prasad J; Manley JL; Bell JC; Duncan PI
    EMBO J; 1996 Jan; 15(2):265-75. PubMed ID: 8617202
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Hydrophobic Core Variations Provide a Structural Framework for Tyrosine Kinase Evolution and Functional Specialization.
    Mohanty S; Oruganty K; Kwon A; Byrne DP; Ferries S; Ruan Z; Hanold LE; Katiyar S; Kennedy EJ; Eyers PA; Kannan N
    PLoS Genet; 2016 Feb; 12(2):e1005885. PubMed ID: 26925779
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Imprint of evolutionary conservation and protein structure variation on the binding function of protein tyrosine kinases.
    Verkhivker GM
    Bioinformatics; 2006 Aug; 22(15):1846-54. PubMed ID: 16720585
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The highly conserved LAMMER/CLK2 protein kinases prevent germ cell overproliferation in Drosophila.
    Zhao S; Chen D; Geng Q; Wang Z
    Dev Biol; 2013 Apr; 376(2):163-70. PubMed ID: 23376537
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.