220 related articles for article (PubMed ID: 26718903)
1. hERG quality control and the long QT syndrome.
Foo B; Williamson B; Young JC; Lukacs G; Shrier A
J Physiol; 2016 May; 594(9):2469-81. PubMed ID: 26718903
[TBL] [Abstract][Full Text] [Related]
2. Mutation-specific peripheral and ER quality control of hERG channel cell-surface expression.
Foo B; Barbier C; Guo K; Vasantharuban J; Lukacs GL; Shrier A
Sci Rep; 2019 Apr; 9(1):6066. PubMed ID: 30988392
[TBL] [Abstract][Full Text] [Related]
3. Trafficking-deficient hERG K⁺ channels linked to long QT syndrome are regulated by a microtubule-dependent quality control compartment in the ER.
Smith JL; McBride CM; Nataraj PS; Bartos DC; January CT; Delisle BP
Am J Physiol Cell Physiol; 2011 Jul; 301(1):C75-85. PubMed ID: 21490315
[TBL] [Abstract][Full Text] [Related]
4. Ubiquitination-dependent quality control of hERG K+ channel with acquired and inherited conformational defect at the plasma membrane.
Apaja PM; Foo B; Okiyoneda T; Valinsky WC; Barriere H; Atanasiu R; Ficker E; Lukacs GL; Shrier A
Mol Biol Cell; 2013 Dec; 24(24):3787-804. PubMed ID: 24152733
[TBL] [Abstract][Full Text] [Related]
5. Long QT syndrome-associated I593R mutation in HERG potassium channel activates ER stress pathways.
Keller SH; Platoshyn O; Yuan JX
Cell Biochem Biophys; 2005; 43(3):365-77. PubMed ID: 16244363
[TBL] [Abstract][Full Text] [Related]
6. [Progress in research on defective protein trafficking and functional restoration in HERG-associated long QT syndrome].
Fang P; Lian J
Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2016 Feb; 33(1):101-4. PubMed ID: 26829745
[TBL] [Abstract][Full Text] [Related]
7. Reciprocal control of hERG stability by Hsp70 and Hsc70 with implication for restoration of LQT2 mutant stability.
Li P; Ninomiya H; Kurata Y; Kato M; Miake J; Yamamoto Y; Igawa O; Nakai A; Higaki K; Toyoda F; Wu J; Horie M; Matsuura H; Yoshida A; Shirayoshi Y; Hiraoka M; Hisatome I
Circ Res; 2011 Feb; 108(4):458-68. PubMed ID: 21183741
[TBL] [Abstract][Full Text] [Related]
8. Hsp90 prevents interaction between CHIP and HERG proteins to facilitate maturation of wild-type and mutant HERG proteins.
Iwai C; Li P; Kurata Y; Hoshikawa Y; Morikawa K; Maharani N; Higaki K; Sasano T; Notsu T; Ishido Y; Miake J; Yamamoto Y; Shirayoshi Y; Ninomiya H; Nakai A; Murata S; Yoshida A; Yamamoto K; Hiraoka M; Hisatome I
Cardiovasc Res; 2013 Dec; 100(3):520-8. PubMed ID: 23963841
[TBL] [Abstract][Full Text] [Related]
9. Pharmacological correction of long QT-linked mutations in KCNH2 (hERG) increases the trafficking of Kv11.1 channels stored in the transitional endoplasmic reticulum.
Smith JL; Reloj AR; Nataraj PS; Bartos DC; Schroder EA; Moss AJ; Ohno S; Horie M; Anderson CL; January CT; Delisle BP
Am J Physiol Cell Physiol; 2013 Nov; 305(9):C919-30. PubMed ID: 23864605
[TBL] [Abstract][Full Text] [Related]
10. Role of the cytosolic chaperones Hsp70 and Hsp90 in maturation of the cardiac potassium channel HERG.
Ficker E; Dennis AT; Wang L; Brown AM
Circ Res; 2003 Jun; 92(12):e87-100. PubMed ID: 12775586
[TBL] [Abstract][Full Text] [Related]
11. HERG channel trafficking.
Ficker E; Dennis A; Kuryshev Y; Wible BA; Brown AM
Novartis Found Symp; 2005; 266():57-69; discussion 70-4, 95-9. PubMed ID: 16050262
[TBL] [Abstract][Full Text] [Related]
12. Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanism.
Anderson CL; Delisle BP; Anson BD; Kilby JA; Will ML; Tester DJ; Gong Q; Zhou Z; Ackerman MJ; January CT
Circulation; 2006 Jan; 113(3):365-73. PubMed ID: 16432067
[TBL] [Abstract][Full Text] [Related]
13. LQT2 nonsense mutations generate trafficking defective NH2-terminally truncated channels by the reinitiation of translation.
Stump MR; Gong Q; Zhou Z
Am J Physiol Heart Circ Physiol; 2013 Nov; 305(9):H1397-404. PubMed ID: 23997099
[TBL] [Abstract][Full Text] [Related]
14. hERG channel trafficking: novel targets in drug-induced long QT syndrome.
Dennis A; Wang L; Wan X; Ficker E
Biochem Soc Trans; 2007 Nov; 35(Pt 5):1060-3. PubMed ID: 17956279
[TBL] [Abstract][Full Text] [Related]
15. C-terminal HERG (LQT2) mutations disrupt IKr channel regulation through 14-3-3epsilon.
Choe CU; Schulze-Bahr E; Neu A; Xu J; Zhu ZI; Sauter K; Bähring R; Priori S; Guicheney P; Mönnig G; Neapolitano C; Heidemann J; Clancy CE; Pongs O; Isbrandt D
Hum Mol Genet; 2006 Oct; 15(19):2888-902. PubMed ID: 16923798
[TBL] [Abstract][Full Text] [Related]
16. L539 fs/47, a truncated mutation of human ether-a-go-go-related gene (hERG), decreases hERG ion channel currents in HEK 293 cells.
Zhang A; Sun C; Zhang L; Lv Y; Xue X; Li G; Cui C; Yan GX
Clin Exp Pharmacol Physiol; 2013 Jan; 40(1):28-36. PubMed ID: 23134353
[TBL] [Abstract][Full Text] [Related]
17. Identification and functional characterization of the human ether-a-go-go-related gene Q738X mutant associated with hereditary long QT syndrome type 2.
Han SN; Yang SH; Zhang Y; Sun XY; Duan YY; Hu XJ; Fan TL; Huang CZ; Yang G; Zhang Z; Zhang L
Int J Mol Med; 2014 Sep; 34(3):810-5. PubMed ID: 24993425
[TBL] [Abstract][Full Text] [Related]
18. Bag1 Co-chaperone Promotes TRC8 E3 Ligase-dependent Degradation of Misfolded Human Ether a Go-Go-related Gene (hERG) Potassium Channels.
Hantouche C; Williamson B; Valinsky WC; Solomon J; Shrier A; Young JC
J Biol Chem; 2017 Feb; 292(6):2287-2300. PubMed ID: 27998983
[TBL] [Abstract][Full Text] [Related]
19. Retention in the endoplasmic reticulum as a mechanism of dominant-negative current suppression in human long QT syndrome.
Ficker E; Dennis AT; Obejero-Paz CA; Castaldo P; Taglialatela M; Brown AM
J Mol Cell Cardiol; 2000 Dec; 32(12):2327-37. PubMed ID: 11113008
[TBL] [Abstract][Full Text] [Related]
20. Trafficking-deficient G572R-hERG and E637K-hERG activate stress and clearance pathways in endoplasmic reticulum.
Wang Y; Huang X; Zhou J; Yang X; Li D; Mao H; Sun HH; Liu N; Lian J
PLoS One; 2012; 7(1):e29885. PubMed ID: 22242185
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]