263 related articles for article (PubMed ID: 26723172)
1. The role of cytochrome P450 BM3 phenylalanine-87 and threonine-268 in binding organic hydroperoxides.
Roberts AG; Katayama J; Kaspera R; Ledwitch KV; Le Trong I; Stenkamp RE; Thompson JA; Totah RA
Biochim Biophys Acta; 2016 Apr; 1860(4):669-77. PubMed ID: 26723172
[TBL] [Abstract][Full Text] [Related]
2. Key mutations alter the cytochrome P450 BM3 conformational landscape and remove inherent substrate bias.
Butler CF; Peet C; Mason AE; Voice MW; Leys D; Munro AW
J Biol Chem; 2013 Aug; 288(35):25387-25399. PubMed ID: 23828198
[TBL] [Abstract][Full Text] [Related]
3. Crystallographic insights into a cobalt (III) sepulchrate based alternative cofactor system of P450 BM3 monooxygenase.
Panneerselvam S; Shehzad A; Mueller-Dieckmann J; Wilmanns M; Bocola M; Davari MD; Schwaneberg U
Biochim Biophys Acta Proteins Proteom; 2018 Jan; 1866(1):134-140. PubMed ID: 28739446
[TBL] [Abstract][Full Text] [Related]
4. Active site substitution A82W improves the regioselectivity of steroid hydroxylation by cytochrome P450 BM3 mutants as rationalized by spin relaxation nuclear magnetic resonance studies.
Rea V; Kolkman AJ; Vottero E; Stronks EJ; Ampt KA; Honing M; Vermeulen NP; Wijmenga SS; Commandeur JN
Biochemistry; 2012 Jan; 51(3):750-60. PubMed ID: 22208729
[TBL] [Abstract][Full Text] [Related]
5. Control of the stereo-selectivity of styrene epoxidation by cytochrome P450 BM3 using structure-based mutagenesis.
Huang WC; Cullis PM; Raven EL; Roberts GC
Metallomics; 2011 Apr; 3(4):410-6. PubMed ID: 21240430
[TBL] [Abstract][Full Text] [Related]
6. Characterization of the structure and interactions of P450 BM3 using hybrid mass spectrometry approaches.
Jeffreys LN; Pacholarz KJ; Johannissen LO; Girvan HM; Barran PE; Voice MW; Munro AW
J Biol Chem; 2020 May; 295(22):7595-7607. PubMed ID: 32303637
[TBL] [Abstract][Full Text] [Related]
7. Expression, purification, and characterization of Bacillus subtilis cytochromes P450 CYP102A2 and CYP102A3: flavocytochrome homologues of P450 BM3 from Bacillus megaterium.
Gustafsson MC; Roitel O; Marshall KR; Noble MA; Chapman SK; Pessegueiro A; Fulco AJ; Cheesman MR; von Wachenfeldt C; Munro AW
Biochemistry; 2004 May; 43(18):5474-87. PubMed ID: 15122913
[TBL] [Abstract][Full Text] [Related]
8. Phe393 mutants of cytochrome P450 BM3 with modified heme redox potentials have altered heme vinyl and propionate conformations.
Chen Z; Ost TW; Schelvis JP
Biochemistry; 2004 Feb; 43(7):1798-808. PubMed ID: 14967021
[TBL] [Abstract][Full Text] [Related]
9. Filling a hole in cytochrome P450 BM3 improves substrate binding and catalytic efficiency.
Huang WC; Westlake AC; Maréchal JD; Joyce MG; Moody PC; Roberts GC
J Mol Biol; 2007 Oct; 373(3):633-51. PubMed ID: 17868686
[TBL] [Abstract][Full Text] [Related]
10. Insights into regioselective metabolism of mefenamic acid by cytochrome P450 BM3 mutants through crystallography, docking, molecular dynamics, and free energy calculations.
Capoferri L; Leth R; ter Haar E; Mohanty AK; Grootenhuis PD; Vottero E; Commandeur JN; Vermeulen NP; Jørgensen FS; Olsen L; Geerke DP
Proteins; 2016 Mar; 84(3):383-96. PubMed ID: 26757175
[TBL] [Abstract][Full Text] [Related]
11. Structural basis for the properties of two single-site proline mutants of CYP102A1 (P450BM3).
Whitehouse CJ; Yang W; Yorke JA; Rowlatt BC; Strong AJ; Blanford CF; Bell SG; Bartlam M; Wong LL; Rao Z
Chembiochem; 2010 Dec; 11(18):2549-56. PubMed ID: 21110374
[TBL] [Abstract][Full Text] [Related]
12. A novel semi-biosynthetic route for artemisinin production using engineered substrate-promiscuous P450(BM3).
Dietrich JA; Yoshikuni Y; Fisher KJ; Woolard FX; Ockey D; McPhee DJ; Renninger NS; Chang MC; Baker D; Keasling JD
ACS Chem Biol; 2009 Apr; 4(4):261-7. PubMed ID: 19271725
[TBL] [Abstract][Full Text] [Related]
13. Electron transfer in flavocytochrome P450 BM3: kinetics of flavin reduction and oxidation, the role of cysteine 999, and relationships with mammalian cytochrome P450 reductase.
Roitel O; Scrutton NS; Munro AW
Biochemistry; 2003 Sep; 42(36):10809-21. PubMed ID: 12962506
[TBL] [Abstract][Full Text] [Related]
14. Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3.
Girvan HM; Levy CW; Williams P; Fisher K; Cheesman MR; Rigby SE; Leys D; Munro AW
Biochem J; 2010 Apr; 427(3):455-66. PubMed ID: 20180779
[TBL] [Abstract][Full Text] [Related]
15. Human P450-like oxidation of diverse proton pump inhibitor drugs by 'gatekeeper' mutants of flavocytochrome P450 BM3.
Butler CF; Peet C; McLean KJ; Baynham MT; Blankley RT; Fisher K; Rigby SE; Leys D; Voice MW; Munro AW
Biochem J; 2014 Jun; 460(2):247-59. PubMed ID: 24588219
[TBL] [Abstract][Full Text] [Related]
16. Optimisation of Cytochrome P450 BM3 Assisted by Consensus-Guided Evolution.
Vincent T; Gaillet B; Garnier A
Appl Biochem Biotechnol; 2021 Sep; 193(9):2893-2914. PubMed ID: 33860879
[TBL] [Abstract][Full Text] [Related]
17. A single mutation in cytochrome P450 BM3 changes substrate orientation in a catalytic intermediate and the regiospecificity of hydroxylation.
Oliver CF; Modi S; Sutcliffe MJ; Primrose WU; Lian LY; Roberts GC
Biochemistry; 1997 Feb; 36(7):1567-72. PubMed ID: 9048540
[TBL] [Abstract][Full Text] [Related]
18. Application of engineered cytochrome P450 mutants as biocatalysts for the synthesis of benzylic and aromatic metabolites of fenamic acid NSAIDs.
Venkataraman H; Verkade-Vreeker MC; Capoferri L; Geerke DP; Vermeulen NP; Commandeur JN
Bioorg Med Chem; 2014 Oct; 22(20):5613-20. PubMed ID: 24999003
[TBL] [Abstract][Full Text] [Related]
19. Modulation of the interaction between human P450 3A4 and B. megaterium reductase via engineered loops.
Castrignanò S; D'Avino S; Di Nardo G; Catucci G; Sadeghi SJ; Gilardi G
Biochim Biophys Acta Proteins Proteom; 2018 Jan; 1866(1):116-125. PubMed ID: 28734977
[TBL] [Abstract][Full Text] [Related]
20. Molecular dynamics simulations of P450 BM3--examination of substrate-induced conformational change.
Chang YT; Loew GH
J Biomol Struct Dyn; 1999 Jun; 16(6):1189-203. PubMed ID: 10447203
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
