218 related articles for article (PubMed ID: 26723888)
1. Ion channel profiling to advance drug discovery and development.
Zou B
Drug Discov Today Technol; 2015 Nov; 18():18-23. PubMed ID: 26723888
[TBL] [Abstract][Full Text] [Related]
2. Predicting changes in cardiac myocyte contractility during early drug discovery with in vitro assays.
Morton MJ; Armstrong D; Abi Gerges N; Bridgland-Taylor M; Pollard CE; Bowes J; Valentin JP
Toxicol Appl Pharmacol; 2014 Sep; 279(2):87-94. PubMed ID: 24952337
[TBL] [Abstract][Full Text] [Related]
3. Targeting cardiac potassium channels for state-of-the-art drug discovery.
Walsh KB
Expert Opin Drug Discov; 2015 Feb; 10(2):157-69. PubMed ID: 25400064
[TBL] [Abstract][Full Text] [Related]
4. High-throughput electrophysiology: an emerging paradigm for ion-channel screening and physiology.
Dunlop J; Bowlby M; Peri R; Vasilyev D; Arias R
Nat Rev Drug Discov; 2008 Apr; 7(4):358-68. PubMed ID: 18356919
[TBL] [Abstract][Full Text] [Related]
5. An impedance-based approach using human iPSC-derived cardiomyocytes significantly improves in vitro prediction of in vivo cardiotox liabilities.
Koci B; Luerman G; Duenbostell A; Kettenhofen R; Bohlen H; Coyle L; Knight B; Ku W; Volberg W; Woska JR; Brown MP
Toxicol Appl Pharmacol; 2017 Aug; 329():121-127. PubMed ID: 28546047
[TBL] [Abstract][Full Text] [Related]
6. High throughput assay technologies for ion channel drug discovery.
Zheng W; Spencer RH; Kiss L
Assay Drug Dev Technol; 2004 Oct; 2(5):543-52. PubMed ID: 15671652
[TBL] [Abstract][Full Text] [Related]
7. Cardiac safety pharmacology: from human ether-a-gogo related gene channel block towards induced pluripotent stem cell based disease models.
Kraushaar U; Meyer T; Hess D; Gepstein L; Mummery CL; Braam SR; Guenther E
Expert Opin Drug Saf; 2012 Mar; 11(2):285-98. PubMed ID: 22103746
[TBL] [Abstract][Full Text] [Related]
8. Cardiac ion channel safety profiling on the IonWorks Quattro automated patch clamp system.
Cao X; Lee YT; Holmqvist M; Lin Y; Ni Y; Mikhailov D; Zhang H; Hogan C; Zhou L; Lu Q; Digan ME; Urban L; Erdemli G
Assay Drug Dev Technol; 2010 Dec; 8(6):766-80. PubMed ID: 21133679
[TBL] [Abstract][Full Text] [Related]
9. Silica Nanoparticles Disturb Ion Channels and Transmembrane Potentials of Cardiomyocytes and Induce Lethal Arrhythmias in Mice.
Liu YQ; Xue SM; Zhang P; Xu LN; Wang DP; Li G; Cao JM
Int J Nanomedicine; 2020; 15():7397-7413. PubMed ID: 33116478
[TBL] [Abstract][Full Text] [Related]
10. Contribution of Automated Technologies to Ion Channel Drug Discovery.
Picones A; Loza-Huerta A; Segura-Chama P; Lara-Figueroa CO
Adv Protein Chem Struct Biol; 2016; 104():357-378. PubMed ID: 27038379
[TBL] [Abstract][Full Text] [Related]
11. Automated patch clamp on mESC-derived cardiomyocytes for cardiotoxicity prediction.
Stoelzle S; Haythornthwaite A; Kettenhofen R; Kolossov E; Bohlen H; George M; Brüggemann A; Fertig N
J Biomol Screen; 2011 Sep; 16(8):910-6. PubMed ID: 21775699
[TBL] [Abstract][Full Text] [Related]
12. CiPA: Ongoing testing, future qualification procedures, and pending issues.
Cavero I; Holzgrefe H
J Pharmacol Toxicol Methods; 2015; 76():27-37. PubMed ID: 26159293
[TBL] [Abstract][Full Text] [Related]
13. New strategies in ion channel screening for drug discovery: are there ways to improve its productivity?
Farre C; Fertig N
Expert Opin Drug Discov; 2014 Oct; 9(10):1103-7. PubMed ID: 25062795
[TBL] [Abstract][Full Text] [Related]
14. Automated electrophysiology in drug discovery.
Priest BT; Swensen AM; McManus OB
Curr Pharm Des; 2007; 13(23):2325-37. PubMed ID: 17692004
[TBL] [Abstract][Full Text] [Related]
15. HTS techniques for patch clamp-based ion channel screening - advances and economy.
Farre C; Fertig N
Expert Opin Drug Discov; 2012 Jun; 7(6):515-24. PubMed ID: 22507077
[TBL] [Abstract][Full Text] [Related]
16. Novel screening techniques for ion channel targeting drugs.
Obergrussberger A; Stölzle-Feix S; Becker N; Brüggemann A; Fertig N; Möller C
Channels (Austin); 2015; 9(6):367-75. PubMed ID: 26556400
[TBL] [Abstract][Full Text] [Related]
17. Mechanisms of distribution and targeting of neuronal ion channels.
Thayer DA; Jan LY
Curr Opin Drug Discov Devel; 2010 Sep; 13(5):559-67. PubMed ID: 20812147
[TBL] [Abstract][Full Text] [Related]
18. State-of-the-art automated patch clamp: heat activation, action potentials, and high throughput in ion channel screening.
Stoelzle-Feix S
Methods Mol Biol; 2014; 1183():65-80. PubMed ID: 25023302
[TBL] [Abstract][Full Text] [Related]
19. Model systems for the discovery and development of antiarrhythmic drugs.
Nattel S; Duker G; Carlsson L
Prog Biophys Mol Biol; 2008; 98(2-3):328-39. PubMed ID: 19038282
[TBL] [Abstract][Full Text] [Related]
20. Advances in ion channel high throughput screening: where are we in 2023?
Dallas ML; Bell D
Expert Opin Drug Discov; 2024 Mar; 19(3):331-337. PubMed ID: 38108110
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]