BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 26725739)

  • 21. Assessing hERG channel inhibition using PatchXpress.
    Ly JQ; Shyy G; Misner DL
    Clin Lab Med; 2007 Mar; 27(1):201-8. PubMed ID: 17416313
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Improved throughput of PatchXpress hERG assay using intracellular potassium fluoride.
    Zeng H; Penniman JR; Kinose F; Kim D; Trepakova ES; Malik MG; Dech SJ; Balasubramanian B; Salata JJ
    Assay Drug Dev Technol; 2008 Apr; 6(2):235-41. PubMed ID: 18471077
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Inhibition of HERG potassium channel current by the class 1a antiarrhythmic agent disopyramide.
    Paul AA; Witchel HJ; Hancox JC
    Biochem Biophys Res Commun; 2001 Feb; 280(5):1243-50. PubMed ID: 11162661
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Inhibition of the current of heterologously expressed HERG potassium channels by imipramine and amitriptyline.
    Teschemacher AG; Seward EP; Hancox JC; Witchel HJ
    Br J Pharmacol; 1999 Sep; 128(2):479-85. PubMed ID: 10510461
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Cardiac ion channel safety profiling on the IonWorks Quattro automated patch clamp system.
    Cao X; Lee YT; Holmqvist M; Lin Y; Ni Y; Mikhailov D; Zhang H; Hogan C; Zhou L; Lu Q; Digan ME; Urban L; Erdemli G
    Assay Drug Dev Technol; 2010 Dec; 8(6):766-80. PubMed ID: 21133679
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Interactions of the antimalarial drug mefloquine with the human cardiac potassium channels KvLQT1/minK and HERG.
    Kang J; Chen XL; Wang L; Rampe D
    J Pharmacol Exp Ther; 2001 Oct; 299(1):290-6. PubMed ID: 11561091
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Industrializing electrophysiology: HT automated patch clamp on SyncroPatch® 96 using instant frozen cells.
    Polonchuk L
    Methods Mol Biol; 2014; 1183():81-92. PubMed ID: 25023303
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Variability in the measurement of hERG potassium channel inhibition: effects of temperature and stimulus pattern.
    Kirsch GE; Trepakova ES; Brimecombe JC; Sidach SS; Erickson HD; Kochan MC; Shyjka LM; Lacerda AE; Brown AM
    J Pharmacol Toxicol Methods; 2004; 50(2):93-101. PubMed ID: 15385083
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Effects of phosphodiesterase (PDE) inhibitors on human ether-a-go-go related gene (hERG) channel activity.
    Yunomae K; Ichisaki S; Matsuo J; Nagayama S; Fukuzaki K; Nagata R; Kito G
    J Appl Toxicol; 2007; 27(1):78-85. PubMed ID: 17146843
    [TBL] [Abstract][Full Text] [Related]  

  • 30. A quantitative assessment of hERG liability as a function of lipophilicity.
    Waring MJ; Johnstone C
    Bioorg Med Chem Lett; 2007 Mar; 17(6):1759-64. PubMed ID: 17239590
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Manual whole-cell patch-clamping of the HERG cardiac K+ channel.
    Chen XL; Kang J; Rampe D
    Methods Mol Biol; 2011; 691():151-63. PubMed ID: 20972752
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Inhibitory effect of rhynchophylline on human ether-a-go-go related gene channel.
    Gui L; Li ZW; Du R; Yuan GH; Li W; Ren FX; Li J; Yang JG
    Sheng Li Xue Bao; 2005 Oct; 57(5):648-52. PubMed ID: 16220205
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Flunarizine is a highly potent inhibitor of cardiac hERG potassium current.
    Trepakova ES; Dech SJ; Salata JJ
    J Cardiovasc Pharmacol; 2006 Feb; 47(2):211-20. PubMed ID: 16495758
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Inhibition of HERG channels by the local anaesthetic articaine.
    Siebrands CC; Friederich P
    Eur J Anaesthesiol; 2007 Feb; 24(2):148-53. PubMed ID: 16938156
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Mechanism of inhibition by olanzapine of cloned hERG potassium channels.
    Lee HJ; Choi JS; Hahn SJ
    Neurosci Lett; 2015 Nov; 609():97-102. PubMed ID: 26484507
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Dynamics of hERG closure allow novel insights into hERG blocking by small molecules.
    Schmidtke P; Ciantar M; Theret I; Ducrot P
    J Chem Inf Model; 2014 Aug; 54(8):2320-33. PubMed ID: 25000969
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Comparative pharmacology of guinea pig cardiac myocyte and cloned hERG (I(Kr)) channel.
    Davie C; Pierre-Valentin J; Pollard C; Standen N; Mitcheson J; Alexander P; Thong B
    J Cardiovasc Electrophysiol; 2004 Nov; 15(11):1302-9. PubMed ID: 15574182
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Channel sialic acids limit hERG channel activity during the ventricular action potential.
    Norring SA; Ednie AR; Schwetz TA; Du D; Yang H; Bennett ES
    FASEB J; 2013 Feb; 27(2):622-31. PubMed ID: 23139156
    [TBL] [Abstract][Full Text] [Related]  

  • 39. A place for high-throughput electrophysiology in cardiac safety: screening hERG cell lines and novel compounds with the ion works HTTM system.
    Guthrie H; Livingston FS; Gubler U; Garippa R
    J Biomol Screen; 2005 Dec; 10(8):832-40. PubMed ID: 16234341
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Iloperidone (Fanapt®), a novel atypical antipsychotic, is a potent HERG blocker and delays cardiac ventricular repolarization at clinically relevant concentration.
    Vigneault P; Pilote S; Patoine D; Simard C; Drolet B
    Pharmacol Res; 2012 Jul; 66(1):60-5. PubMed ID: 22465688
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.