BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

230 related articles for article (PubMed ID: 26727042)

  • 1. Protein Delivery of an Artificial Transcription Factor Restores Widespread Ube3a Expression in an Angelman Syndrome Mouse Brain.
    Bailus BJ; Pyles B; McAlister MM; O'Geen H; Lockwood SH; Adams AN; Nguyen JT; Yu A; Berman RF; Segal DJ
    Mol Ther; 2016 Mar; 24(3):548-55. PubMed ID: 26727042
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transcriptional reprogramming restores UBE3A brain-wide and rescues behavioral phenotypes in an Angelman syndrome mouse model.
    O'Geen H; Beitnere U; Garcia MS; Adhikari A; Cameron DL; Fenton TA; Copping NA; Deng P; Lock S; Halmai JANM; Villegas IJ; Liu J; Wang D; Fink KD; Silverman JL; Segal DJ
    Mol Ther; 2023 Apr; 31(4):1088-1105. PubMed ID: 36641623
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CRISPR/Cas9 directed to the Ube3a antisense transcript improves Angelman syndrome phenotype in mice.
    Schmid RS; Deng X; Panikker P; Msackyi M; Breton C; Wilson JM
    J Clin Invest; 2021 Mar; 131(5):. PubMed ID: 33411694
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Towards a therapy for Angelman syndrome by targeting a long non-coding RNA.
    Meng L; Ward AJ; Chun S; Bennett CF; Beaudet AL; Rigo F
    Nature; 2015 Feb; 518(7539):409-12. PubMed ID: 25470045
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Truncation of Ube3a-ATS unsilences paternal Ube3a and ameliorates behavioral defects in the Angelman syndrome mouse model.
    Meng L; Person RE; Huang W; Zhu PJ; Costa-Mattioli M; Beaudet AL
    PLoS Genet; 2013; 9(12):e1004039. PubMed ID: 24385930
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tissue-specific variation of Ube3a protein expression in rodents and in a mouse model of Angelman syndrome.
    Gustin RM; Bichell TJ; Bubser M; Daily J; Filonova I; Mrelashvili D; Deutch AY; Colbran RJ; Weeber EJ; Haas KF
    Neurobiol Dis; 2010 Sep; 39(3):283-91. PubMed ID: 20423730
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Imprinting effects of UBE3A loss on synaptic gene networks and Wnt signaling pathways.
    Lopez SJ; Laufer BI; Beitnere U; Berg EL; Silverman JL; O'Geen H; Segal DJ; LaSalle JM
    Hum Mol Genet; 2019 Nov; 28(22):3842-3852. PubMed ID: 31625566
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization and structure-activity relationships of indenoisoquinoline-derived topoisomerase I inhibitors in unsilencing the dormant
    Lee HM; Clark EP; Kuijer MB; Cushman M; Pommier Y; Philpot BD
    Mol Autism; 2018; 9():45. PubMed ID: 30140420
    [TBL] [Abstract][Full Text] [Related]  

  • 9. R-loop formation at Snord116 mediates topotecan inhibition of Ube3a-antisense and allele-specific chromatin decondensation.
    Powell WT; Coulson RL; Gonzales ML; Crary FK; Wong SS; Adams S; Ach RA; Tsang P; Yamada NA; Yasui DH; Chédin F; LaSalle JM
    Proc Natl Acad Sci U S A; 2013 Aug; 110(34):13938-43. PubMed ID: 23918391
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Imprinted expression of the murine Angelman syndrome gene, Ube3a, in hippocampal and Purkinje neurons.
    Albrecht U; Sutcliffe JS; Cattanach BM; Beechey CV; Armstrong D; Eichele G; Beaudet AL
    Nat Genet; 1997 Sep; 17(1):75-8. PubMed ID: 9288101
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Adult
    Rotaru DC; van Woerden GM; Wallaard I; Elgersma Y
    J Neurosci; 2018 Sep; 38(37):8011-8030. PubMed ID: 30082419
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Gene Therapy for Angelman Syndrome: Contemporary Approaches and Future Endeavors.
    Tsagkaris C; Papakosta V; Miranda AV; Zacharopoulou L; Danilchenko V; Matiashova L; Dhar A
    Curr Gene Ther; 2020; 19(6):359-366. PubMed ID: 31914913
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ube3a-ATS is an atypical RNA polymerase II transcript that represses the paternal expression of Ube3a.
    Meng L; Person RE; Beaudet AL
    Hum Mol Genet; 2012 Jul; 21(13):3001-12. PubMed ID: 22493002
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ube3a imprinting impairs circadian robustness in Angelman syndrome models.
    Shi SQ; Bichell TJ; Ihrie RA; Johnson CH
    Curr Biol; 2015 Mar; 25(5):537-45. PubMed ID: 25660546
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Maternal disruption of Ube3a leads to increased expression of Ube3a-ATS in trans.
    Landers M; Calciano MA; Colosi D; Glatt-Deeley H; Wagstaff J; Lalande M
    Nucleic Acids Res; 2005; 33(13):3976-84. PubMed ID: 16027444
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antisense oligonucleotide therapy rescues disturbed brain rhythms and sleep in juvenile and adult mouse models of Angelman syndrome.
    Lee D; Chen W; Kaku HN; Zhuo X; Chao ES; Soriano A; Kuncheria A; Flores S; Kim JH; Rivera A; Rigo F; Jafar-Nejad P; Beaudet AL; Caudill MS; Xue M
    Elife; 2023 Jan; 12():. PubMed ID: 36594817
    [No Abstract]   [Full Text] [Related]  

  • 17. Assessing the requirements of prenatal UBE3A expression for rescue of behavioral phenotypes in a mouse model for Angelman syndrome.
    Sonzogni M; Zhai P; Mientjes EJ; van Woerden GM; Elgersma Y
    Mol Autism; 2020 Sep; 11(1):70. PubMed ID: 32948244
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Neurons but not glial cells show reciprocal imprinting of sense and antisense transcripts of Ube3a.
    Yamasaki K; Joh K; Ohta T; Masuzaki H; Ishimaru T; Mukai T; Niikawa N; Ogawa M; Wagstaff J; Kishino T
    Hum Mol Genet; 2003 Apr; 12(8):837-47. PubMed ID: 12668607
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SNURF-SNRPN and UBE3A transcript levels in patients with Angelman syndrome.
    Runte M; Kroisel PM; Gillessen-Kaesbach G; Varon R; Horn D; Cohen MY; Wagstaff J; Horsthemke B; Buiting K
    Hum Genet; 2004 May; 114(6):553-61. PubMed ID: 15014980
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enhanced Nociception in Angelman Syndrome Model Mice.
    McCoy ES; Taylor-Blake B; Aita M; Simon JM; Philpot BD; Zylka MJ
    J Neurosci; 2017 Oct; 37(42):10230-10239. PubMed ID: 28931574
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.