BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 26727270)

  • 1. Small Molecule Inhibitors of Ca(2+)-S100B Reveal Two Protein Conformations.
    Cavalier MC; Ansari MI; Pierce AD; Wilder PT; McKnight LE; Raman EP; Neau DB; Bezawada P; Alasady MJ; Charpentier TH; Varney KM; Toth EA; MacKerell AD; Coop A; Weber DJ
    J Med Chem; 2016 Jan; 59(2):592-608. PubMed ID: 26727270
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification and characterization of small molecule inhibitors of the calcium-dependent S100B-p53 tumor suppressor interaction.
    Markowitz J; Chen I; Gitti R; Baldisseri DM; Pan Y; Udan R; Carrier F; MacKerell AD; Weber DJ
    J Med Chem; 2004 Oct; 47(21):5085-93. PubMed ID: 15456252
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Covalent small molecule inhibitors of Ca(2+)-bound S100B.
    Cavalier MC; Pierce AD; Wilder PT; Alasady MJ; Hartman KG; Neau DB; Foley TL; Jadhav A; Maloney DJ; Simeonov A; Toth EA; Weber DJ
    Biochemistry; 2014 Oct; 53(42):6628-40. PubMed ID: 25268459
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Divalent metal ion complexes of S100B in the absence and presence of pentamidine.
    Charpentier TH; Wilder PT; Liriano MA; Varney KM; Pozharski E; MacKerell AD; Coop A; Toth EA; Weber DJ
    J Mol Biol; 2008 Sep; 382(1):56-73. PubMed ID: 18602402
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Small molecules bound to unique sites in the target protein binding cleft of calcium-bound S100B as characterized by nuclear magnetic resonance and X-ray crystallography.
    Charpentier TH; Wilder PT; Liriano MA; Varney KM; Zhong S; Coop A; Pozharski E; MacKerell AD; Toth EA; Weber DJ
    Biochemistry; 2009 Jul; 48(26):6202-12. PubMed ID: 19469484
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel protein-inhibitor interactions in site 3 of Ca(2+)-bound S100B as discovered by X-ray crystallography.
    Cavalier MC; Melville Z; Aligholizadeh E; Raman EP; Yu W; Fang L; Alasady M; Pierce AD; Wilder PT; MacKerell AD; Weber DJ
    Acta Crystallogr D Struct Biol; 2016 Jun; 72(Pt 6):753-60. PubMed ID: 27303795
    [TBL] [Abstract][Full Text] [Related]  

  • 7. S100B Inhibitor Pentamidine Attenuates Reactive Gliosis and Reduces Neuronal Loss in a Mouse Model of Alzheimer's Disease.
    Cirillo C; Capoccia E; Iuvone T; Cuomo R; Sarnelli G; Steardo L; Esposito G
    Biomed Res Int; 2015; 2015():508342. PubMed ID: 26295040
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Specificity of Molecular Fragments Binding to S100B versus S100A1 as Identified by NMR and Site Identification by Ligand Competitive Saturation (SILCS).
    Young BD; Yu W; Rodríguez DJV; Varney KM; MacKerell AD; Weber DJ
    Molecules; 2021 Jan; 26(2):. PubMed ID: 33450915
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Theoretical study on binding of S100B protein.
    Gieldon A; Mori M; Del Conte R
    J Mol Model; 2007 Nov; 13(11):1123-31. PubMed ID: 17713798
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural changes in the C-terminus of Ca2+-bound rat S100B (beta beta) upon binding to a peptide derived from the C-terminal regulatory domain of p53.
    Rustandi RR; Baldisseri DM; Drohat AC; Weber DJ
    Protein Sci; 1999 Sep; 8(9):1743-51. PubMed ID: 10493575
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The effects of CapZ peptide (TRTK-12) binding to S100B-Ca2+ as examined by NMR and X-ray crystallography.
    Charpentier TH; Thompson LE; Liriano MA; Varney KM; Wilder PT; Pozharski E; Toth EA; Weber DJ
    J Mol Biol; 2010 Mar; 396(5):1227-43. PubMed ID: 20053360
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The evolution of S100B inhibitors for the treatment of malignant melanoma.
    Hartman KG; McKnight LE; Liriano MA; Weber DJ
    Future Med Chem; 2013 Jan; 5(1):97-109. PubMed ID: 23256816
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The crystal structures of human S100B in the zinc- and calcium-loaded state at three pH values reveal zinc ligand swapping.
    Ostendorp T; Diez J; Heizmann CW; Fritz G
    Biochim Biophys Acta; 2011 May; 1813(5):1083-91. PubMed ID: 20950652
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The S100B Inhibitor Pentamidine Ameliorates Clinical Score and Neuropathology of Relapsing-Remitting Multiple Sclerosis Mouse Model.
    Di Sante G; Amadio S; Sampaolese B; Clementi ME; Valentini M; Volonté C; Casalbore P; Ria F; Michetti F
    Cells; 2020 Mar; 9(3):. PubMed ID: 32197530
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Ca(2+)-dependent interaction of S100B(beta beta) with a peptide derived from p53.
    Rustandi RR; Drohat AC; Baldisseri DM; Wilder PT; Weber DJ
    Biochemistry; 1998 Feb; 37(7):1951-60. PubMed ID: 9485322
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of small-molecule inhibitors of the human S100B-p53 interaction and evaluation of their activity in human melanoma cells.
    Yoshimura C; Miyafusa T; Tsumoto K
    Bioorg Med Chem; 2013 Mar; 21(5):1109-15. PubMed ID: 23375094
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Multimodal Structural Distribution of the p53 C-Terminal Domain upon Binding to S100B via a Generalized Ensemble Method: From Disorder to Extradisorder.
    Iida S; Kawabata T; Kasahara K; Nakamura H; Higo J
    J Chem Theory Comput; 2019 Apr; 15(4):2597-2607. PubMed ID: 30855964
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pentamidine niosomes thwart S100B effects in human colon carcinoma biopsies favouring wtp53 rescue.
    Seguella L; Rinaldi F; Marianecci C; Capuano R; Pesce M; Annunziata G; Casano F; Bassotti G; Sidoni A; Milone M; Aprea G; de Palma GD; Carafa M; Pesce M; Esposito G; Sarnelli G
    J Cell Mol Med; 2020 Mar; 24(5):3053-3063. PubMed ID: 32022398
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-Based Discovery of a Novel Pentamidine-Related Inhibitor of the Calcium-Binding Protein S100B.
    McKnight LE; Raman EP; Bezawada P; Kudrimoti S; Wilder PT; Hartman KG; Godoy-Ruiz R; Toth EA; Coop A; Mackerell AD; Weber DJ
    ACS Med Chem Lett; 2012 Dec; 3(12):975-979. PubMed ID: 23264854
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Solution structure of rat apo-S100B(beta beta) as determined by NMR spectroscopy.
    Drohat AC; Amburgey JC; Abildgaard F; Starich MR; Baldisseri D; Weber DJ
    Biochemistry; 1996 Sep; 35(36):11577-88. PubMed ID: 8794737
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.