BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 26731610)

  • 1. Polyketide Ring Expansion Mediated by a Thioesterase, Chain Elongation and Cyclization Domain, in Azinomycin Biosynthesis: Characterization of AziB and AziG.
    Mori S; Simkhada D; Zhang H; Erb MS; Zhang Y; Williams H; Fedoseyenko D; Russell WK; Kim D; Fleer N; Ealick SE; Watanabe CM
    Biochemistry; 2016 Feb; 55(4):704-14. PubMed ID: 26731610
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Biosynthesis of 3-methoxy-5-methyl naphthoic acid and its incorporation into the antitumor antibiotic azinomycin B.
    Ding W; Deng W; Tang M; Zhang Q; Tang G; Bi Y; Liu W
    Mol Biosyst; 2010 Jun; 6(6):1071-81. PubMed ID: 20485749
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of the azinomycin B biosynthetic gene cluster revealing a different iterative type I polyketide synthase for naphthoate biosynthesis.
    Zhao Q; He Q; Ding W; Tang M; Kang Q; Yu Y; Deng W; Zhang Q; Fang J; Tang G; Liu W
    Chem Biol; 2008 Jul; 15(7):693-705. PubMed ID: 18635006
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A labile point in mutant amphotericin polyketide synthases.
    Khan N; Rawlings B; Caffrey P
    Biotechnol Lett; 2011 Jun; 33(6):1121-6. PubMed ID: 21267757
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cloning and analysis of a type II polyketide synthase gene cluster from Streptomyces toxytricini NRRL 15,443.
    Yoo A; Demirev AV; Lee JS; Kim SD; Nam DH
    J Microbiol; 2006 Dec; 44(6):649-54. PubMed ID: 17205043
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparative characterization of the lactimidomycin and iso-migrastatin biosynthetic machineries revealing unusual features for acyltransferase-less type I polyketide synthases and providing an opportunity to engineer new analogues.
    Seo JW; Ma M; Kwong T; Ju J; Lim SK; Jiang H; Lohman JR; Yang C; Cleveland J; Zazopoulos E; Farnet CM; Shen B
    Biochemistry; 2014 Dec; 53(49):7854-65. PubMed ID: 25405956
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Elucidation of Piericidin A1 biosynthetic locus revealed a thioesterase-dependent mechanism of α-pyridone ring formation.
    Liu Q; Yao F; Chooi YH; Kang Q; Xu W; Li Y; Shao Y; Shi Y; Deng Z; Tang Y; You D
    Chem Biol; 2012 Feb; 19(2):243-53. PubMed ID: 22365607
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Probing the Role of N-Acetyl-glutamyl 5-Phosphate, an Acyl Phosphate, in the Construction of the Azabicycle Moiety of the Azinomycins.
    Nepal KK; Lee RP; Rezenom YH; Watanabe CM
    Biochemistry; 2015 Jul; 54(29):4415-8. PubMed ID: 26161634
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A single module type I polyketide synthase directs de novo macrolactone biogenesis during galbonolide biosynthesis in Streptomyces galbus.
    Kim HJ; Karki S; Kwon SY; Park SH; Nahm BH; Kim YK; Kwon HJ
    J Biol Chem; 2014 Dec; 289(50):34557-68. PubMed ID: 25336658
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Chain initiation in the leinamycin-producing hybrid nonribosomal peptide/polyketide synthetase from Streptomyces atroolivaceus S-140. Discrete, monofunctional adenylation enzyme and peptidyl carrier protein that directly load D-alanine.
    Tang GL; Cheng YQ; Shen B
    J Biol Chem; 2007 Jul; 282(28):20273-82. PubMed ID: 17502372
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Polyketide antibiotics produced by polyketide synthase in streptomyces--a review].
    Chen M; Wang G; Dai S; Xie L; Li X
    Wei Sheng Wu Xue Bao; 2009 Dec; 49(12):1555-63. PubMed ID: 20222438
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Unraveling the iterative type I polyketide synthases hidden in
    Wang B; Guo F; Huang C; Zhao H
    Proc Natl Acad Sci U S A; 2020 Apr; 117(15):8449-8454. PubMed ID: 32217738
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure and function of an iterative polyketide synthase thioesterase domain catalyzing Claisen cyclization in aflatoxin biosynthesis.
    Korman TP; Crawford JM; Labonte JW; Newman AG; Wong J; Townsend CA; Tsai SC
    Proc Natl Acad Sci U S A; 2010 Apr; 107(14):6246-51. PubMed ID: 20332208
    [TBL] [Abstract][Full Text] [Related]  

  • 14. N-carbamoylation of 2,4-diaminobutyrate reroutes the outcome in padanamide biosynthesis.
    Du YL; Dalisay DS; Andersen RJ; Ryan KS
    Chem Biol; 2013 Aug; 20(8):1002-11. PubMed ID: 23911586
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural and biochemical characterization of ZhuI aromatase/cyclase from the R1128 polyketide pathway.
    Ames BD; Lee MY; Moody C; Zhang W; Tang Y; Tsai SC
    Biochemistry; 2011 Oct; 50(39):8392-406. PubMed ID: 21870821
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evaluating Ketoreductase Exchanges as a Means of Rationally Altering Polyketide Stereochemistry.
    Annaval T; Paris C; Leadlay PF; Jacob C; Weissman KJ
    Chembiochem; 2015 Jun; 16(9):1357-64. PubMed ID: 25851784
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An in vitro platform for engineering and harnessing modular polyketide synthases.
    Miyazawa T; Hirsch M; Zhang Z; Keatinge-Clay AT
    Nat Commun; 2020 Jan; 11(1):80. PubMed ID: 31900404
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Flexible enzymatic activation of artificial polyketide extender units by Streptomyces cinnamonensis into the monensin biosynthetic pathway.
    Möller D; Kushnir S; Grote M; Ismail-Ali A; Koopmans KRM; Calo F; Heinrich S; Diehl B; Schulz F
    Lett Appl Microbiol; 2018 Sep; 67(3):226-234. PubMed ID: 29927502
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Essential role of the donor acyl carrier protein in stereoselective chain translocation to a fully reducing module of the nanchangmycin polyketide synthase.
    Guo X; Liu T; Deng Z; Cane DE
    Biochemistry; 2012 Jan; 51(4):879-87. PubMed ID: 22229794
    [TBL] [Abstract][Full Text] [Related]  

  • 20. An efficient method for creation and functional analysis of libraries of hybrid type I polyketide synthases.
    Kim BS; Sherman DH; Reynolds KA
    Protein Eng Des Sel; 2004 Mar; 17(3):277-84. PubMed ID: 15067106
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.