BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

225 related articles for article (PubMed ID: 26735910)

  • 1. Cardanol-derived AChE inhibitors: Towards the development of dual binding derivatives for Alzheimer's disease.
    Lemes LFN; de Andrade Ramos G; de Oliveira AS; da Silva FMR; de Castro Couto G; da Silva Boni M; Guimarães MJR; Souza INO; Bartolini M; Andrisano V; do Nascimento Nogueira PC; Silveira ER; Brand GD; Soukup O; Korábečný J; Romeiro NC; Castro NG; Bolognesi ML; Romeiro LAS
    Eur J Med Chem; 2016 Jan; 108():687-700. PubMed ID: 26735910
    [TBL] [Abstract][Full Text] [Related]  

  • 2. New cholinesterase inhibitors for Alzheimer's disease: Structure Activity Studies (SARs) and molecular docking of isoquinolone and azepanone derivatives.
    Bacalhau P; San Juan AA; Marques CS; Peixoto D; Goth A; Guarda C; Silva M; Arantes S; Caldeira AT; Martins R; Burke AJ
    Bioorg Chem; 2016 Aug; 67():1-8. PubMed ID: 27231829
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New potential AChE inhibitor candidates.
    de Paula AA; Martins JB; dos Santos ML; Nascente Lde C; Romeiro LA; Areas TF; Vieira KS; Gambôa NF; Castro NG; Gargano R
    Eur J Med Chem; 2009 Sep; 44(9):3754-9. PubMed ID: 19446931
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pterostilbene-O-acetamidoalkylbenzylamines derivatives as novel dual inhibitors of cholinesterase with anti-β-amyloid aggregation and antioxidant properties for the treatment of Alzheimer's disease.
    Li Y; Qiang X; Li Y; Yang X; Luo L; Xiao G; Cao Z; Tan Z; Deng Y
    Bioorg Med Chem Lett; 2016 Apr; 26(8):2035-9. PubMed ID: 26947607
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, pharmacological assessment, molecular modeling and in silico studies of fused tricyclic coumarin derivatives as a new family of multifunctional anti-Alzheimer agents.
    Shaik JB; Palaka BK; Penumala M; Kotapati KV; Devineni SR; Eadlapalli S; Darla MM; Ampasala DR; Vadde R; Amooru GD
    Eur J Med Chem; 2016 Jan; 107():219-32. PubMed ID: 26588065
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and evaluation of novel cinnamic acid derivatives bearing N-benzyl pyridinium moiety as multifunctional cholinesterase inhibitors for Alzheimer's disease.
    Lan JS; Hou JW; Liu Y; Ding Y; Zhang Y; Li L; Zhang T
    J Enzyme Inhib Med Chem; 2017 Dec; 32(1):776-788. PubMed ID: 28585866
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and biological evaluation of 2-acetyl-5-O-(amino-alkyl)phenol derivatives as multifunctional agents for the treatment of Alzheimer's disease.
    Sang Z; Wang K; Wang H; Wang H; Ma Q; Han X; Ye M; Yu L; Liu W
    Bioorg Med Chem Lett; 2017 Nov; 27(22):5046-5052. PubMed ID: 29033233
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Syntheses, cholinesterases inhibition, and molecular docking studies of pyrido[2,3-b]pyrazine derivatives.
    Hameed A; Zehra ST; Shah SJ; Khan KM; Alharthy RD; Furtmann N; Bajorath J; Tahir MN; Iqbal J
    Chem Biol Drug Des; 2015 Nov; 86(5):1115-20. PubMed ID: 25951978
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel pyridazinone derivatives as butyrylcholinesterase inhibitors.
    Dundar Y; Kuyrukcu O; Eren G; Senol Deniz FS; Onkol T; Orhan IE
    Bioorg Chem; 2019 Nov; 92():103304. PubMed ID: 31561108
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis and biological evaluation of novel donepezil-coumarin hybrids as multi-target agents for the treatment of Alzheimer's disease.
    Xie SS; Lan JS; Wang X; Wang ZM; Jiang N; Li F; Wu JJ; Wang J; Kong LY
    Bioorg Med Chem; 2016 Apr; 24(7):1528-39. PubMed ID: 26917219
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, biological evaluation and molecular modeling of new tetrahydroacridine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.
    Bajda M; Jończyk J; Malawska B; Czarnecka K; Girek M; Olszewska P; Sikora J; Mikiciuk-Olasik E; Skibiński R; Gumieniczek A; Szymański P
    Bioorg Med Chem; 2015 Sep; 23(17):5610-8. PubMed ID: 26242241
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis and biological evaluation of 3,4-dihydro-2(1H)-quinoline-O-alkylamine derivatives as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
    Sang Z; Pan W; Wang K; Ma Q; Yu L; Liu W
    Bioorg Med Chem; 2017 Jun; 25(12):3006-3017. PubMed ID: 28487125
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and evaluation of 7-substituted coumarin derivatives as multimodal monoamine oxidase-B and cholinesterase inhibitors for the treatment of Alzheimer's disease.
    Joubert J; Foka GB; Repsold BP; Oliver DW; Kapp E; Malan SF
    Eur J Med Chem; 2017 Jan; 125():853-864. PubMed ID: 27744252
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, pharmacological assessment, and molecular modeling of 6-chloro-pyridonepezils: new dual AChE inhibitors as potential drugs for the treatment of Alzheimer's disease.
    Samadi A; de la Fuente Revenga M; Pérez C; Iriepa I; Moraleda I; Rodríguez-Franco MI; Marco-Contelles J
    Eur J Med Chem; 2013 Sep; 67():64-74. PubMed ID: 23838422
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine.
    Samadi A; de los Ríos C; Bolea I; Chioua M; Iriepa I; Moraleda I; Bartolini M; Andrisano V; Gálvez E; Valderas C; Unzeta M; Marco-Contelles J
    Eur J Med Chem; 2012 Jun; 52():251-62. PubMed ID: 22503231
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tetrahydroacridine derivatives with fluorobenzoic acid moiety as multifunctional agents for Alzheimer's disease treatment.
    Czarnecka K; Szymański P; Girek M; Mikiciuk-Olasik E; Skibiński R; Kabziński J; Majsterek I; Malawska B; Jończyk J; Bajda M
    Bioorg Chem; 2017 Jun; 72():315-322. PubMed ID: 28501648
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting β-amyloid, tau, and cholinesterase pathologies.
    Di Pietro O; Pérez-Areales FJ; Juárez-Jiménez J; Espargaró A; Clos MV; Pérez B; Lavilla R; Sabaté R; Luque FJ; Muñoz-Torrero D
    Eur J Med Chem; 2014 Sep; 84():107-17. PubMed ID: 25016233
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rational design of carbamate-based dual binding site and central AChE inhibitors by a "biooxidisable" prodrug approach: Synthesis, in vitro evaluation and docking studies.
    Ţînţaş ML; Gembus V; Alix F; Barré A; Coadou G; Truong L; Sebban M; Papamicaël C; Oulyadi H; Levacher V
    Eur J Med Chem; 2018 Jul; 155():171-182. PubMed ID: 29886321
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 1,2,3,4-Tetrahydrobenzo[h][1,6]naphthyridines as a new family of potent peripheral-to-midgorge-site inhibitors of acetylcholinesterase: synthesis, pharmacological evaluation and mechanistic studies.
    Di Pietro O; Viayna E; Vicente-García E; Bartolini M; Ramón R; Juárez-Jiménez J; Clos MV; Pérez B; Andrisano V; Luque FJ; Lavilla R; Muñoz-Torrero D
    Eur J Med Chem; 2014 Feb; 73():141-52. PubMed ID: 24389509
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and pharmacological evaluation of donepezil-based agents as new cholinesterase/monoamine oxidase inhibitors for the potential application against Alzheimer's disease.
    Li F; Wang ZM; Wu JJ; Wang J; Xie SS; Lan JS; Xu W; Kong LY; Wang XB
    J Enzyme Inhib Med Chem; 2016; 31(sup3):41-53. PubMed ID: 27384289
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.