BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

266 related articles for article (PubMed ID: 26739507)

  • 1. Receptor tyrosine kinase gene expression profiles of Ewing sarcomas reveal ROR1 as a potential therapeutic target in metastatic disease.
    Potratz J; Tillmanns A; Berning P; Korsching E; Schaefer C; Lechtape B; Schleithoff C; Unland R; Schäfer KL; Müller-Tidow C; Jürgens H; Dirksen U
    Mol Oncol; 2016 May; 10(5):677-92. PubMed ID: 26739507
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Receptor tyrosine kinase profiling of ischemic heart identifies ROR1 as a potential therapeutic target.
    Heliste J; Jokilammi A; Paatero I; Chakroborty D; Stark C; Savunen T; Laaksonen M; Elenius K
    BMC Cardiovasc Disord; 2018 Oct; 18(1):196. PubMed ID: 30342492
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ERBB4 confers metastatic capacity in Ewing sarcoma.
    Mendoza-Naranjo A; El-Naggar A; Wai DH; Mistry P; Lazic N; Ayala FR; da Cunha IW; Rodriguez-Viciana P; Cheng H; Tavares Guerreiro Fregnani JH; Reynolds P; Arceci RJ; Nicholson A; Triche TJ; Soares FA; Flanagan AM; Wang YZ; Strauss SJ; Sorensen PH
    EMBO Mol Med; 2013 Jul; 5(7):1087-102. PubMed ID: 23681745
    [TBL] [Abstract][Full Text] [Related]  

  • 4. IGF1R- and ROR1-Specific CAR T Cells as a Potential Therapy for High Risk Sarcomas.
    Huang X; Park H; Greene J; Pao J; Mulvey E; Zhou SX; Albert CM; Moy F; Sachdev D; Yee D; Rader C; Hamby CV; Loeb DM; Cairo MS; Zhou X
    PLoS One; 2015; 10(7):e0133152. PubMed ID: 26173023
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting the ROR1 and ROR2 receptors in epithelial ovarian cancer inhibits cell migration and invasion.
    Henry C; Llamosas E; Knipprath-Meszaros A; Schoetzau A; Obermann E; Fuenfschilling M; Caduff R; Fink D; Hacker N; Ward R; Heinzelmann-Schwarz V; Ford C
    Oncotarget; 2015 Nov; 6(37):40310-26. PubMed ID: 26515598
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Wnt5a and ROR1 activate non-canonical Wnt signaling via RhoA in TCF3-PBX1 acute lymphoblastic leukemia and highlight new treatment strategies via Bcl-2 co-targeting.
    Karvonen H; Perttilä R; Niininen W; Hautanen V; Barker H; Murumägi A; Heckman CA; Ungureanu D
    Oncogene; 2019 Apr; 38(17):3288-3300. PubMed ID: 30631148
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of Wnt/β-Catenin in Ewing Sarcoma Cells Antagonizes EWS/ETS Function and Promotes Phenotypic Transition to More Metastatic Cell States.
    Pedersen EA; Menon R; Bailey KM; Thomas DG; Van Noord RA; Tran J; Wang H; Qu PP; Hoering A; Fearon ER; Chugh R; Lawlor ER
    Cancer Res; 2016 Sep; 76(17):5040-53. PubMed ID: 27364557
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting the Receptor Tyrosine Kinase ROR1 by Small Molecules.
    Hojjat-Farsangi M; Moshfegh A; Schultz J; Norin M; Olin T; Österborg A; Mellstedt H
    Handb Exp Pharmacol; 2021; 269():75-99. PubMed ID: 34490515
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The CXCR4 antagonist plerixafor (AMD3100) promotes proliferation of Ewing sarcoma cell lines in vitro and activates receptor tyrosine kinase signaling.
    Berning P; Schaefer C; Clemens D; Korsching E; Dirksen U; Potratz J
    Cell Commun Signal; 2018 May; 16(1):21. PubMed ID: 29776413
    [TBL] [Abstract][Full Text] [Related]  

  • 10. EphA2 receptor is a key player in the metastatic onset of Ewing sarcoma.
    Garcia-Monclús S; López-Alemany R; Almacellas-Rabaiget O; Herrero-Martín D; Huertas-Martinez J; Lagares-Tena L; Alba-Pavón P; Hontecillas-Prieto L; Mora J; de Álava E; Rello-Varona S; Giangrande PH; Tirado OM
    Int J Cancer; 2018 Sep; 143(5):1188-1201. PubMed ID: 29582409
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CIC-rearranged Sarcomas: A Study of 20 Cases and Comparisons With Ewing Sarcomas.
    Yoshida A; Goto K; Kodaira M; Kobayashi E; Kawamoto H; Mori T; Yoshimoto S; Endo O; Kodama N; Kushima R; Hiraoka N; Motoi T; Kawai A
    Am J Surg Pathol; 2016 Mar; 40(3):313-23. PubMed ID: 26685084
    [TBL] [Abstract][Full Text] [Related]  

  • 12. EphA2-induced angiogenesis in ewing sarcoma cells works through bFGF production and is dependent on caveolin-1.
    Sáinz-Jaspeado M; Huertas-Martinez J; Lagares-Tena L; Martin Liberal J; Mateo-Lozano S; de Alava E; de Torres C; Mora J; Del Muro XG; Tirado OM
    PLoS One; 2013; 8(8):e71449. PubMed ID: 23951165
    [TBL] [Abstract][Full Text] [Related]  

  • 13. miR-130b directly targets ARHGAP1 to drive activation of a metastatic CDC42-PAK1-AP1 positive feedback loop in Ewing sarcoma.
    Satterfield L; Shuck R; Kurenbekova L; Allen-Rhoades W; Edwards D; Huang S; Rajapakshe K; Coarfa C; Donehower LA; Yustein JT
    Int J Cancer; 2017 Nov; 141(10):2062-2075. PubMed ID: 28748534
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ROR1 is expressed in human breast cancer and associated with enhanced tumor-cell growth.
    Zhang S; Chen L; Cui B; Chuang HY; Yu J; Wang-Rodriguez J; Tang L; Chen G; Basak GW; Kipps TJ
    PLoS One; 2012; 7(3):e31127. PubMed ID: 22403610
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ror family receptor tyrosine kinases regulate the maintenance of neural progenitor cells in the developing neocortex.
    Endo M; Doi R; Nishita M; Minami Y
    J Cell Sci; 2012 Apr; 125(Pt 8):2017-29. PubMed ID: 22328498
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The histone demethylase KDM3A, and its downstream target MCAM, promote Ewing Sarcoma cell migration and metastasis.
    Sechler M; Parrish JK; Birks DK; Jedlicka P
    Oncogene; 2017 Jul; 36(29):4150-4160. PubMed ID: 28319067
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel CIC-FOXO4 gene fusion in undifferentiated small round cell sarcoma: a genetically distinct variant of Ewing-like sarcoma.
    Sugita S; Arai Y; Tonooka A; Hama N; Totoki Y; Fujii T; Aoyama T; Asanuma H; Tsukahara T; Kaya M; Shibata T; Hasegawa T
    Am J Surg Pathol; 2014 Nov; 38(11):1571-6. PubMed ID: 25007147
    [TBL] [Abstract][Full Text] [Related]  

  • 18. High-throughput RNAi screen in Ewing sarcoma cells identifies leucine rich repeats and WD repeat domain containing 1 (LRWD1) as a regulator of EWS-FLI1 driven cell viability.
    He T; Surdez D; Rantala JK; Haapa-Paananen S; Ban J; Kauer M; Tomazou E; Fey V; Alonso J; Kovar H; Delattre O; Iljin K
    Gene; 2017 Jan; 596():137-146. PubMed ID: 27760381
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Focal adhesion kinase confers pro-migratory and antiapoptotic properties and is a potential therapeutic target in Ewing sarcoma.
    Steinestel K; Trautmann M; Jansen EP; Dirksen U; Rehkämper J; Mikesch JH; Gerke JS; Orth MF; Sannino G; Arteaga MF; Rossig C; Wardelmann E; Grünewald TGP; Hartmann W
    Mol Oncol; 2020 Feb; 14(2):248-260. PubMed ID: 31811703
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Silencing of Receptor Tyrosine Kinase ROR1 Inhibits Tumor-Cell Proliferation via PI3K/AKT/mTOR Signaling Pathway in Lung Adenocarcinoma.
    Liu Y; Yang H; Chen T; Luo Y; Xu Z; Li Y; Yang J
    PLoS One; 2015; 10(5):e0127092. PubMed ID: 25978653
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.