480 related articles for article (PubMed ID: 26740621)
1. Ubiquilin-mediated Small Molecule Inhibition of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling.
Coffey RT; Shi Y; Long MJ; Marr MT; Hedstrom L
J Biol Chem; 2016 Mar; 291(10):5221-33. PubMed ID: 26740621
[TBL] [Abstract][Full Text] [Related]
2. GSK-3 directly regulates phospho-4EBP1 in renal cell carcinoma cell-line: an intrinsic subcellular mechanism for resistance to mTORC1 inhibition.
Ito H; Ichiyanagi O; Naito S; Bilim VN; Tomita Y; Kato T; Nagaoka A; Tsuchiya N
BMC Cancer; 2016 Jul; 16():393. PubMed ID: 27387559
[TBL] [Abstract][Full Text] [Related]
3. The synergistic inhibition of breast cancer proliferation by combined treatment with 4EGI-1 and MK2206.
Wang H; Huang F; Wang J; Wang P; Lv W; Hong L; Li S; Zhou J
Cell Cycle; 2015; 14(2):232-42. PubMed ID: 25607647
[TBL] [Abstract][Full Text] [Related]
4. 4EBP1/eIF4E and p70S6K/RPS6 axes play critical and distinct roles in hepatocarcinogenesis driven by AKT and N-Ras proto-oncogenes in mice.
Wang C; Cigliano A; Jiang L; Li X; Fan B; Pilo MG; Liu Y; Gui B; Sini M; Smith JW; Dombrowski F; Calvisi DF; Evert M; Chen X
Hepatology; 2015 Jan; 61(1):200-13. PubMed ID: 25145583
[TBL] [Abstract][Full Text] [Related]
5. Increased milk protein synthesis in response to exogenous growth hormone is associated with changes in mechanistic (mammalian) target of rapamycin (mTOR)C1-dependent and independent cell signaling.
Sciascia Q; Pacheco D; McCoard SA
J Dairy Sci; 2013 Apr; 96(4):2327-2338. PubMed ID: 23462168
[TBL] [Abstract][Full Text] [Related]
6. Luteinizing hormone/human chorionic gonadotropin-mediated activation of mTORC1 signaling is required for androgen synthesis by theca-interstitial cells.
Palaniappan M; Menon KM
Mol Endocrinol; 2012 Oct; 26(10):1732-42. PubMed ID: 22827930
[TBL] [Abstract][Full Text] [Related]
7. Rapamycin attenuates BAFF-extended proliferation and survival via disruption of mTORC1/2 signaling in normal and neoplastic B-lymphoid cells.
Zeng Q; Qin S; Zhang H; Liu B; Qin J; Wang X; Zhang R; Liu C; Dong X; Zhang S; Huang S; Chen L
J Cell Physiol; 2018 Jan; 233(1):516-529. PubMed ID: 28300280
[TBL] [Abstract][Full Text] [Related]
8. Relieving autophagy and 4EBP1 from rapamycin resistance.
Nyfeler B; Bergman P; Triantafellow E; Wilson CJ; Zhu Y; Radetich B; Finan PM; Klionsky DJ; Murphy LO
Mol Cell Biol; 2011 Jul; 31(14):2867-76. PubMed ID: 21576371
[TBL] [Abstract][Full Text] [Related]
9. mTORC1 signalling and eIF4E/4E-BP1 translation initiation factor stoichiometry influence recombinant protein productivity from GS-CHOK1 cells.
Jossé L; Xie J; Proud CG; Smales CM
Biochem J; 2016 Dec; 473(24):4651-4664. PubMed ID: 27760840
[TBL] [Abstract][Full Text] [Related]
10. MNK1 pathway activity maintains protein synthesis in rapalog-treated gliomas.
Grzmil M; Huber RM; Hess D; Frank S; Hynx D; Moncayo G; Klein D; Merlo A; Hemmings BA
J Clin Invest; 2014 Feb; 124(2):742-54. PubMed ID: 24401275
[TBL] [Abstract][Full Text] [Related]
11. mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs.
Dowling RJ; Topisirovic I; Alain T; Bidinosti M; Fonseca BD; Petroulakis E; Wang X; Larsson O; Selvaraj A; Liu Y; Kozma SC; Thomas G; Sonenberg N
Science; 2010 May; 328(5982):1172-6. PubMed ID: 20508131
[TBL] [Abstract][Full Text] [Related]
12. PRAS40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complex.
Fonseca BD; Smith EM; Lee VH; MacKintosh C; Proud CG
J Biol Chem; 2007 Aug; 282(34):24514-24. PubMed ID: 17604271
[TBL] [Abstract][Full Text] [Related]
13. Curcumin disrupts the Mammalian target of rapamycin-raptor complex.
Beevers CS; Chen L; Liu L; Luo Y; Webster NJ; Huang S
Cancer Res; 2009 Feb; 69(3):1000-8. PubMed ID: 19176385
[TBL] [Abstract][Full Text] [Related]
14. ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding.
Dunlop EA; Hunt DK; Acosta-Jaquez HA; Fingar DC; Tee AR
Autophagy; 2011 Jul; 7(7):737-47. PubMed ID: 21460630
[TBL] [Abstract][Full Text] [Related]
15. A dual mTORC1 and mTORC2 inhibitor shows antitumor activity in esophageal squamous cell carcinoma cells and sensitizes them to cisplatin.
Huang Y; Xi Q; Chen Y; Wang J; Peng P; Xia S; Yu S
Anticancer Drugs; 2013 Oct; 24(9):889-98. PubMed ID: 23838676
[TBL] [Abstract][Full Text] [Related]
16. mTORC1 drives HIF-1α and VEGF-A signalling via multiple mechanisms involving 4E-BP1, S6K1 and STAT3.
Dodd KM; Yang J; Shen MH; Sampson JR; Tee AR
Oncogene; 2015 Apr; 34(17):2239-50. PubMed ID: 24931163
[TBL] [Abstract][Full Text] [Related]
17. S6K1 alternative splicing modulates its oncogenic activity and regulates mTORC1.
Ben-Hur V; Denichenko P; Siegfried Z; Maimon A; Krainer A; Davidson B; Karni R
Cell Rep; 2013 Jan; 3(1):103-15. PubMed ID: 23273915
[TBL] [Abstract][Full Text] [Related]
18. Hepatitis C virus NS5A binds to the mRNA cap-binding eukaryotic translation initiation 4F (eIF4F) complex and up-regulates host translation initiation machinery through eIF4E-binding protein 1 inactivation.
George A; Panda S; Kudmulwar D; Chhatbar SP; Nayak SC; Krishnan HH
J Biol Chem; 2012 Feb; 287(7):5042-58. PubMed ID: 22184107
[TBL] [Abstract][Full Text] [Related]
19. High-dose rapamycin induces apoptosis in human cancer cells by dissociating mTOR complex 1 and suppressing phosphorylation of 4E-BP1.
Yellen P; Saqcena M; Salloum D; Feng J; Preda A; Xu L; Rodrik-Outmezguine V; Foster DA
Cell Cycle; 2011 Nov; 10(22):3948-56. PubMed ID: 22071574
[TBL] [Abstract][Full Text] [Related]
20. PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding.
Wang L; Harris TE; Roth RA; Lawrence JC
J Biol Chem; 2007 Jul; 282(27):20036-44. PubMed ID: 17510057
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
