These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Sequence-specific deamidation: isolation and biochemical characterization of succinimide intermediates of recombinant hirudin. Bischoff R; Lepage P; Jaquinod M; Cauet G; Acker-Klein M; Clesse D; Laporte M; Bayol A; Van Dorsselaer A; Roitsch C Biochemistry; 1993 Jan; 32(2):725-34. PubMed ID: 8422378 [TBL] [Abstract][Full Text] [Related]
3. Isolation and purification of novel hirudins from the leech Hirudinaria manillensis by high-performance liquid chromatography. Steiner V; Knecht R; Gruetter M; Raschdorf F; Gassmann E; Maschler R J Chromatogr; 1990 Sep; 530(2):273-82. PubMed ID: 2079503 [TBL] [Abstract][Full Text] [Related]
4. Purification and identification of recombinant hirudin and its degradation products expressed in Pichia pastoris. Zhou WB; Zhang YX Prep Biochem Biotechnol; 2004 Aug; 34(3):239-52. PubMed ID: 15461140 [TBL] [Abstract][Full Text] [Related]
5. Mass spectrometry analyses of recombinant hirudins (7 kDa). Van Dorsselaer A; Lepage P; Bitsch F; Whitechurch O; Riehl-Bellon N; Fraisse D; Green B; Roitsch C Biochemistry; 1989 Apr; 28(7):2949-56. PubMed ID: 2742822 [TBL] [Abstract][Full Text] [Related]
6. Robust preparative-scale extracellular production of hirudin in Escherichia coli and its purification and characterization. Huang C; Zhang X; Qu J; Zhang P; Tan S J Ind Microbiol Biotechnol; 2012 Oct; 39(10):1487-94. PubMed ID: 22847924 [TBL] [Abstract][Full Text] [Related]
7. Characterization of the deamidated forms of recombinant hirudin. Tuong A; Maftouh M; Ponthus C; Whitechurch O; Roitsch C; Picard C Biochemistry; 1992 Sep; 31(35):8291-9. PubMed ID: 1525166 [TBL] [Abstract][Full Text] [Related]
8. Hirudin and hirudin-based peptides. Stone SR; Maraganore JM Methods Enzymol; 1993; 223():312-36. PubMed ID: 8271960 [No Abstract] [Full Text] [Related]
9. Purification and biochemical characterization of recombinant hirudin produced by Saccharomyces cerevisiae. Riehl-Bellon N; Carvallo D; Acker M; Van Dorsselaer A; Marquet M; Loison G; Lemoine Y; Brown SW; Courtney M; Roitsch C Biochemistry; 1989 Apr; 28(7):2941-9. PubMed ID: 2663064 [TBL] [Abstract][Full Text] [Related]
10. Liquid secondary ion mass spectrometry applied to structural confirmation of enzymically prepared C-terminal-truncated derivatives of recombinant hirudin. Maftouh M; Ponthus C; Tuong A; Picard C J Chromatogr; 1991 Jan; 562(1-2):421-34. PubMed ID: 2026708 [TBL] [Abstract][Full Text] [Related]
12. Antithrombin activity of the hirudin N-terminal core domain residues 1-43. Chang JY; Schlaeppi JM; Stone SR FEBS Lett; 1990 Jan; 260(2):209-12. PubMed ID: 2404798 [TBL] [Abstract][Full Text] [Related]
13. Rapid purification and revised amino-terminal sequence of hirudin: a specific thrombin inhibitor of the bloodsucking leech. Mao SJ; Yates MT; Blankenship DT; Cardin AD; Krstenansky JL; Lovenberg W; Jackson RL Anal Biochem; 1987 Mar; 161(2):514-8. PubMed ID: 3578808 [TBL] [Abstract][Full Text] [Related]
14. Recombinant hirudin: kinetic mechanism for the inhibition of human thrombin. Stone SR; Hofsteenge J Protein Eng; 1991 Feb; 4(3):295-300. PubMed ID: 1857714 [TBL] [Abstract][Full Text] [Related]
15. Expression, purification and characterization of multigram amounts of a recombinant hybrid HV1-HV2 hirudin variant expressed in Saccharomyces cerevisiae. Lehman ED; Joyce JG; Bailey FJ; Markus HZ; Schultz LD; Dunwiddie CT; Jacobson MA; Miller WJ Protein Expr Purif; 1993 Jun; 4(3):247-55. PubMed ID: 8518563 [TBL] [Abstract][Full Text] [Related]
16. Novel hirudin variants from the leech Hirudinaria manillensis. Amino acid sequence, cDNA cloning and genomic organization. Scacheri E; Nitti G; Valsasina B; Orsini G; Visco C; Ferrera M; Sawyer RT; Sarmientos P Eur J Biochem; 1993 May; 214(1):295-304. PubMed ID: 7685281 [TBL] [Abstract][Full Text] [Related]
17. CX-397, a novel recombinant hirudin analog having a hybrid sequence of hirudin variants-1 and -3. Komatsu Y; Misawa S; Sukesada A; Ohba Y; Hayashi H Biochem Biophys Res Commun; 1993 Oct; 196(2):773-9. PubMed ID: 8240353 [TBL] [Abstract][Full Text] [Related]
18. Site specific radioiodination of recombinant hirudin. Tuong A; Maftouh M; Picard C; Gachon M Anal Biochem; 1990 Sep; 189(2):186-91. PubMed ID: 2281861 [TBL] [Abstract][Full Text] [Related]
19. Production of recombinant hirudin by high cell density fed-batch cultivations of a Saccharomyces cerevisiae strain: physiological considerations during the bioprocess design. Mendoza-Vega O; Hebert C; Brown SW J Biotechnol; 1994 Feb; 32(3):249-59. PubMed ID: 7764718 [TBL] [Abstract][Full Text] [Related]
20. [Fermentation, purification and identification of recombinant RGD-Hirudin]. Mo W; Zhang YL; Wang LS; Yang XY; Song HY Sheng Wu Gong Cheng Xue Bao; 2004 Jan; 20(1):126-9. PubMed ID: 16108503 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]