127 related articles for article (PubMed ID: 26742834)
1. Effects and mechanisms of potent caspase-1 inhibitor VX765 treatment on collagen-induced arthritis in mice.
Zhang Y; Zheng Y
Clin Exp Rheumatol; 2016; 34(1):111-8. PubMed ID: 26742834
[TBL] [Abstract][Full Text] [Related]
2. Protection against cartilage and bone destruction by systemic interleukin-4 treatment in established murine type II collagen-induced arthritis.
Joosten LA; Lubberts E; Helsen MM; Saxne T; Coenen-de Roo CJ; Heinegård D; van den Berg WB
Arthritis Res; 1999; 1(1):81-91. PubMed ID: 11056663
[TBL] [Abstract][Full Text] [Related]
3. Effect of VX‑765 on the transcriptome profile of mice spinal cords with acute injury.
Chen J; Chen YQ; Wang SN; Duan FX; Shi YJ; Ding SQ; Hu JG; Lü HZ
Mol Med Rep; 2020 Jul; 22(1):33-42. PubMed ID: 32377730
[TBL] [Abstract][Full Text] [Related]
4. VX765, a Specific Caspase-1 Inhibitor, Alleviates Lung Ischemia Reperfusion Injury by Suppressing Endothelial Pyroptosis and Barrier Dysfunction.
Wu S; Li Z; Ye M; Liu C; Liu H; He X; Qin Y; Liang F; Pan L; Lin F
Biomed Res Int; 2021; 2021():4525988. PubMed ID: 34977239
[TBL] [Abstract][Full Text] [Related]
5. VX765 alleviates dextran sulfate sodium-induced colitis in mice by suppressing caspase-1-mediated pyroptosis.
Wang L; Dong X; Feng S; Pan H; Jang X; Chen L; Zhao Y; Chen W; Huang Z
Int Immunopharmacol; 2022 Jan; 102():108405. PubMed ID: 34865993
[TBL] [Abstract][Full Text] [Related]
6. ASC plays a role in the priming phase of the immune response to type II collagen in collagen-induced arthritis.
Yamazaki H; Takeoka M; Kitazawa M; Ehara T; Itano N; Kato H; Taniguchi S
Rheumatol Int; 2012 Jun; 32(6):1625-32. PubMed ID: 21331573
[TBL] [Abstract][Full Text] [Related]
7. Caspase-1 inhibition prevents neuronal death by targeting the canonical inflammasome pathway of pyroptosis in a murine model of cerebral ischemia.
Li J; Hao JH; Yao D; Li R; Li XF; Yu ZY; Luo X; Liu XH; Wang MH; Wang W
CNS Neurosci Ther; 2020 Sep; 26(9):925-939. PubMed ID: 32343048
[TBL] [Abstract][Full Text] [Related]
8. Iridoid glycosides from the flowers of Gentiana macrophylla Pall. ameliorate collagen-induced arthritis in rats.
Jia N; Chu W; Li Y; Ding L; Duan J; Cui J; Cao S; Zhao C; Wu Y; Wen A
J Ethnopharmacol; 2016 Aug; 189():1-9. PubMed ID: 27180880
[TBL] [Abstract][Full Text] [Related]
9. Therapeutic effects of Caragana pruinosa Kom. roots extract on type II collagen-induced arthritis in rats.
Peng W; Wang L; Qiu X; Jiang Y; Han T; Pan L; Jia X; Qin L; Zheng C
J Ethnopharmacol; 2016 Sep; 191():1-8. PubMed ID: 27292194
[TBL] [Abstract][Full Text] [Related]
10. Transgenic mice over-expressing carbonic anhydrase I showed aggravated joint inflammation and tissue destruction.
Zheng Y; Wang L; Zhang W; Xu H; Chang X
BMC Musculoskelet Disord; 2012 Dec; 13():256. PubMed ID: 23256642
[TBL] [Abstract][Full Text] [Related]
11. A novel histone deacetylase 6-selective inhibitor suppresses synovial inflammation and joint destruction in a collagen antibody-induced arthritis mouse model.
Lee J; Hong EC; Jeong H; Hwang JW; Kim H; Bae EK; Ahn JK; Choi YL; Han J; Cha HS; Koh EM
Int J Rheum Dis; 2015 Jun; 18(5):514-23. PubMed ID: 25530272
[TBL] [Abstract][Full Text] [Related]
12. Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion.
Lubberts E; Koenders MI; Oppers-Walgreen B; van den Bersselaar L; Coenen-de Roo CJ; Joosten LA; van den Berg WB
Arthritis Rheum; 2004 Feb; 50(2):650-9. PubMed ID: 14872510
[TBL] [Abstract][Full Text] [Related]
13. Cannabinoid 1 Receptor Antagonists Play a Neuroprotective Role in Chronic Alcoholic Hippocampal Injury Related to Pyroptosis Pathway.
Zhang D; Liu X; Dong X; Zhu R; Jiang J; Ye Y; Jiang Y
Alcohol Clin Exp Res; 2020 Aug; 44(8):1585-1597. PubMed ID: 32524615
[TBL] [Abstract][Full Text] [Related]
14. Crocin exerts anti-inflammatory and anti-arthritic effects on type II collagen-induced arthritis in rats.
Liu W; Sun Y; Cheng Z; Guo Y; Liu P; Wen Y
Pharm Biol; 2018 Dec; 56(1):209-216. PubMed ID: 29540097
[TBL] [Abstract][Full Text] [Related]
15. A selective CB
Bai J; Ge G; Wang Y; Zhang W; Wang Q; Wang W; Guo X; Yu B; Xu Y; Yang H; Zhu X; Wang M; Geng D
Biomed Pharmacother; 2019 Aug; 116():109025. PubMed ID: 31154267
[TBL] [Abstract][Full Text] [Related]
16. Adiponectin exerts a potent anti-arthritic effect and insulin resistance in collagen-induced arthritic rats.
Wu D; Hua B; Fang Z; Liu J; Liu N; Ma Y
Int J Rheum Dis; 2018 Aug; 21(8):1496-1503. PubMed ID: 28752573
[TBL] [Abstract][Full Text] [Related]
17. The caspase-1 inhibitor VX765 upregulates connexin 43 expression and improves cell-cell communication after myocardial infarction via suppressing the IL-1β/p38 MAPK pathway.
Su XL; Wang SH; Komal S; Cui LG; Ni RC; Zhang LR; Han SN
Acta Pharmacol Sin; 2022 Sep; 43(9):2289-2301. PubMed ID: 35132192
[TBL] [Abstract][Full Text] [Related]
18. Efficacy of daily compared to intermittent administration of IL-1Ra for protection against bone and cartilage destruction in collagen-challenged mice.
Inoue K; Masuko-Hongo K; Okamoto M; Nishioka K
Clin Exp Rheumatol; 2003; 21(1):33-9. PubMed ID: 12673887
[TBL] [Abstract][Full Text] [Related]
19. Interleukin-19 blockade attenuates collagen-induced arthritis in rats.
Hsu YH; Hsieh PP; Chang MS
Rheumatology (Oxford); 2012 Mar; 51(3):434-42. PubMed ID: 21719423
[TBL] [Abstract][Full Text] [Related]
20. (S)-1-((S)-2-{[1-(4-amino-3-chloro-phenyl)-methanoyl]-amino}-3,3-dimethyl-butanoyl)-pyrrolidine-2-carboxylic acid ((2R,3S)-2-ethoxy-5-oxo-tetrahydro-furan-3-yl)-amide (VX-765), an orally available selective interleukin (IL)-converting enzyme/caspase-1 inhibitor, exhibits potent anti-inflammatory activities by inhibiting the release of IL-1beta and IL-18.
Wannamaker W; Davies R; Namchuk M; Pollard J; Ford P; Ku G; Decker C; Charifson P; Weber P; Germann UA; Kuida K; Randle JC
J Pharmacol Exp Ther; 2007 May; 321(2):509-16. PubMed ID: 17289835
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]