These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

233 related articles for article (PubMed ID: 26743335)

  • 21. Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways.
    Yecies JL; Zhang HH; Menon S; Liu S; Yecies D; Lipovsky AI; Gorgun C; Kwiatkowski DJ; Hotamisligil GS; Lee CH; Manning BD
    Cell Metab; 2011 Jul; 14(1):21-32. PubMed ID: 21723501
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Activation of mTORC1 is essential for β-adrenergic stimulation of adipose browning.
    Liu D; Bordicchia M; Zhang C; Fang H; Wei W; Li JL; Guilherme A; Guntur K; Czech MP; Collins S
    J Clin Invest; 2016 May; 126(5):1704-16. PubMed ID: 27018708
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Raptor, a positive regulatory subunit of mTOR complex 1, is a novel phosphoprotein of the rDNA transcription machinery in nucleoli and chromosomal nucleolus organizer regions (NORs).
    Vazquez-Martin A; Cufí S; Oliveras-Ferraros C; Menendez JA
    Cell Cycle; 2011 Sep; 10(18):3140-52. PubMed ID: 21900751
    [TBL] [Abstract][Full Text] [Related]  

  • 24. PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding.
    Wang L; Harris TE; Roth RA; Lawrence JC
    J Biol Chem; 2007 Jul; 282(27):20036-44. PubMed ID: 17510057
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Selective interference of mTORC1/RAPTOR protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism with Akt and autophagy induction.
    Ito M; Yurube T; Kakutani K; Maeno K; Takada T; Terashima Y; Kakiuchi Y; Takeoka Y; Miyazaki S; Kuroda R; Nishida K
    Osteoarthritis Cartilage; 2017 Dec; 25(12):2134-2146. PubMed ID: 28888905
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Procyanidin B2 ameliorates free fatty acids-induced hepatic steatosis through regulating TFEB-mediated lysosomal pathway and redox state.
    Su H; Li Y; Hu D; Xie L; Ke H; Zheng X; Chen W
    Free Radic Biol Med; 2018 Oct; 126():269-286. PubMed ID: 30142454
    [TBL] [Abstract][Full Text] [Related]  

  • 27. RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
    Gordon BS; Kazi AA; Coleman CS; Dennis MD; Chau V; Jefferson LS; Kimball SR
    Cell Signal; 2014 Mar; 26(3):461-7. PubMed ID: 24316235
    [TBL] [Abstract][Full Text] [Related]  

  • 28. GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling.
    Stretton C; Hoffmann TM; Munson MJ; Prescott A; Taylor PM; Ganley IG; Hundal HS
    Biochem J; 2015 Sep; 470(2):207-21. PubMed ID: 26348909
    [TBL] [Abstract][Full Text] [Related]  

  • 29. O-GlcNAcylation of Raptor transduces glucose signals to mTORC1.
    Xu C; Pan X; Wang D; Guan Y; Yang W; Chen X; Liu Y
    Mol Cell; 2023 Aug; 83(16):3027-3040.e11. PubMed ID: 37541260
    [TBL] [Abstract][Full Text] [Related]  

  • 30. ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding.
    Dunlop EA; Hunt DK; Acosta-Jaquez HA; Fingar DC; Tee AR
    Autophagy; 2011 Jul; 7(7):737-47. PubMed ID: 21460630
    [TBL] [Abstract][Full Text] [Related]  

  • 31. PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.
    Woo SY; Kim DH; Jun CB; Kim YM; Haar EV; Lee SI; Hegg JW; Bandhakavi S; Griffin TJ; Kim DH
    J Biol Chem; 2007 Aug; 282(35):25604-12. PubMed ID: 17599906
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Inhibition of PI3K-Akt-mTOR signaling in glioblastoma by mTORC1/2 inhibitors.
    Fan QW; Weiss WA
    Methods Mol Biol; 2012; 821():349-59. PubMed ID: 22125077
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Raptor binds the SAIN (Shc and IRS-1 NPXY binding) domain of insulin receptor substrate-1 (IRS-1) and regulates the phosphorylation of IRS-1 at Ser-636/639 by mTOR.
    Tzatsos A
    J Biol Chem; 2009 Aug; 284(34):22525-34. PubMed ID: 19561084
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Fibroblast growth factor 21 improves hepatic insulin sensitivity by inhibiting mammalian target of rapamycin complex 1 in mice.
    Gong Q; Hu Z; Zhang F; Cui A; Chen X; Jiang H; Gao J; Chen X; Han Y; Liang Q; Ye D; Shi L; Chin YE; Wang Y; Xiao H; Guo F; Liu Y; Zang M; Xu A; Li Y
    Hepatology; 2016 Aug; 64(2):425-38. PubMed ID: 26926384
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Cell-type-dependent regulation of mTORC1 by REDD1 and the tumor suppressors TSC1/TSC2 and LKB1 in response to hypoxia.
    Wolff NC; Vega-Rubin-de-Celis S; Xie XJ; Castrillon DH; Kabbani W; Brugarolas J
    Mol Cell Biol; 2011 May; 31(9):1870-84. PubMed ID: 21383064
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Postprandial hepatic lipid metabolism requires signaling through Akt2 independent of the transcription factors FoxA2, FoxO1, and SREBP1c.
    Wan M; Leavens KF; Saleh D; Easton RM; Guertin DA; Peterson TR; Kaestner KH; Sabatini DM; Birnbaum MJ
    Cell Metab; 2011 Oct; 14(4):516-27. PubMed ID: 21982711
    [TBL] [Abstract][Full Text] [Related]  

  • 37. MicroRNA-206 prevents hepatosteatosis and hyperglycemia by facilitating insulin signaling and impairing lipogenesis.
    Wu H; Zhang T; Pan F; Steer CJ; Li Z; Chen X; Song G
    J Hepatol; 2017 Apr; 66(4):816-824. PubMed ID: 28025059
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Crosstalk between beta-adrenergic and insulin signaling mediates mechanistic target of rapamycin hyperactivation in liver of high-fat diet-fed male mice.
    Ashraf S; Ashraf N; Yilmaz G; Harmancey R
    Physiol Rep; 2021 Jul; 9(13):e14958. PubMed ID: 34231324
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Hepatic Activation of the FAM3C-HSF1-CaM Pathway Attenuates Hyperglycemia of Obese Diabetic Mice.
    Chen Z; Ding L; Yang W; Wang J; Chen L; Chang Y; Geng B; Cui Q; Guan Y; Yang J
    Diabetes; 2017 May; 66(5):1185-1197. PubMed ID: 28246289
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Ellagic acid ameliorates AKT-driven hepatic steatosis in mice by suppressing de novo lipogenesis via the AKT/SREBP-1/FASN pathway.
    Zhang C; Hu J; Sheng L; Yuan M; Wu Y; Chen L; Wang G; Qiu Z
    Food Funct; 2019 Jun; 10(6):3410-3420. PubMed ID: 31123744
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.