345 related articles for article (PubMed ID: 26758418)
1. EM23, a natural sesquiterpene lactone, targets thioredoxin reductase to activate JNK and cell death pathways in human cervical cancer cells.
Shao FY; Wang S; Li HY; Chen WB; Wang GC; Ma DL; Wong NS; Xiao H; Liu QY; Zhou GX; Li YL; Li MM; Wang YF; Liu Z
Oncotarget; 2016 Feb; 7(6):6790-808. PubMed ID: 26758418
[TBL] [Abstract][Full Text] [Related]
2. EM23, A Natural Sesquiterpene Lactone from Elephantopus mollis, Induces Apoptosis in Human Myeloid Leukemia Cells through Thioredoxin- and Reactive Oxygen Species-Mediated Signaling Pathways.
Li H; Li M; Wang G; Shao F; Chen W; Xia C; Wang S; Li Y; Zhou G; Liu Z
Front Pharmacol; 2016; 7():77. PubMed ID: 27064563
[TBL] [Abstract][Full Text] [Related]
3. B5, a thioredoxin reductase inhibitor, induces apoptosis in human cervical cancer cells by suppressing the thioredoxin system, disrupting mitochondrion-dependent pathways and triggering autophagy.
Shao FY; Du ZY; Ma DL; Chen WB; Fu WY; Ruan BB; Rui W; Zhang JX; Wang S; Wong NS; Xiao H; Li MM; Liu X; Liu QY; Zhou XD; Yan HZ; Wang YF; Chen CY; Liu Z; Chen HY
Oncotarget; 2015 Oct; 6(31):30939-56. PubMed ID: 26439985
[TBL] [Abstract][Full Text] [Related]
4. Promotion of HeLa cells apoptosis by cynaropicrin involving inhibition of thioredoxin reductase and induction of oxidative stress.
Liu T; Zhang J; Han X; Xu J; Wu Y; Fang J
Free Radic Biol Med; 2019 May; 135():216-226. PubMed ID: 30880248
[TBL] [Abstract][Full Text] [Related]
5. Securinine disturbs redox homeostasis and elicits oxidative stress-mediated apoptosis via targeting thioredoxin reductase.
Zhang J; Yao J; Peng S; Li X; Fang J
Biochim Biophys Acta Mol Basis Dis; 2017 Jan; 1863(1):129-138. PubMed ID: 27777067
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of thioredoxin reductase by alantolactone prompts oxidative stress-mediated apoptosis of HeLa cells.
Zhang J; Li Y; Duan D; Yao J; Gao K; Fang J
Biochem Pharmacol; 2016 Feb; 102():34-44. PubMed ID: 26686580
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of thioredoxin reductase induces apoptosis in neuronal cell lines: role of glutathione and the MKK4/JNK pathway.
Seyfried J; Wüllner U
Biochem Biophys Res Commun; 2007 Aug; 359(3):759-64. PubMed ID: 17559804
[TBL] [Abstract][Full Text] [Related]
8. Molecular bases of thioredoxin and thioredoxin reductase-mediated prooxidant actions of (-)-epigallocatechin-3-gallate.
Zhang H; Cao D; Cui W; Ji M; Qian X; Zhong L
Free Radic Biol Med; 2010 Dec; 49(12):2010-8. PubMed ID: 20951799
[TBL] [Abstract][Full Text] [Related]
9. Cytotoxicity induced by inhibition of thioredoxin reductases via multiple signaling pathways: role of cytosolic phospholipase A(2)alpha-dependent and -independent release of arachidonic acid.
Kurosawa T; Nakamura H; Yamaura E; Fujino H; Matsuzawa Y; Kawashima T; Murayama T
J Cell Physiol; 2009 Jun; 219(3):606-16. PubMed ID: 19170071
[TBL] [Abstract][Full Text] [Related]
10. Auranofin, an inhibitor of thioredoxin reductase, induces apoptosis in hepatocellular carcinoma Hep3B cells by generation of reactive oxygen species.
Hwang-Bo H; Jeong JW; Han MH; Park C; Hong SH; Kim GY; Moon SK; Cheong J; Kim WJ; Yoo YH; Choi YH
Gen Physiol Biophys; 2017 Apr; 36(2):117-128. PubMed ID: 28218611
[TBL] [Abstract][Full Text] [Related]
11. Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase.
Gandin V; Fernandes AP; Rigobello MP; Dani B; Sorrentino F; Tisato F; Björnstedt M; Bindoli A; Sturaro A; Rella R; Marzano C
Biochem Pharmacol; 2010 Jan; 79(2):90-101. PubMed ID: 19665452
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of thioredoxin reductase by mansonone F analogues: Implications for anticancer activity.
Liu Z; Huang SL; Li MM; Huang ZS; Lee KS; Gu LQ
Chem Biol Interact; 2009 Jan; 177(1):48-57. PubMed ID: 18822278
[TBL] [Abstract][Full Text] [Related]
13. Thioredoxin system inhibitors as mediators of apoptosis for cancer therapy.
Tonissen KF; Di Trapani G
Mol Nutr Food Res; 2009 Jan; 53(1):87-103. PubMed ID: 18979503
[TBL] [Abstract][Full Text] [Related]
14. The role of thioredoxin reductase and glutathione reductase in plumbagin-induced, reactive oxygen species-mediated apoptosis in cancer cell lines.
Hwang GH; Ryu JM; Jeon YJ; Choi J; Han HJ; Lee YM; Lee S; Bae JS; Jung JW; Chang W; Kim LK; Jee JG; Lee MY
Eur J Pharmacol; 2015 Oct; 765():384-93. PubMed ID: 26341012
[TBL] [Abstract][Full Text] [Related]
15. A thioredoxin reductase and/or thioredoxin system-based mechanism for antioxidant effects of ambroxol.
Huang J; Xu J; Tian L; Zhong L
Biochimie; 2014 Feb; 97():92-103. PubMed ID: 24103200
[TBL] [Abstract][Full Text] [Related]
16. Targeting thioredoxin reductase by deoxyelephantopin from Elephantopus scaber triggers cancer cell apoptosis.
Duan D; Wang Y; Pan D; Wang L; Xiao J; Song P; Jin X; Wang X
Arch Biochem Biophys; 2021 Oct; 711():109028. PubMed ID: 34509463
[TBL] [Abstract][Full Text] [Related]
17. A TrxR inhibiting gold(I) NHC complex induces apoptosis through ASK1-p38-MAPK signaling in pancreatic cancer cells.
Cheng X; Holenya P; Can S; Alborzinia H; Rubbiani R; Ott I; Wölfl S
Mol Cancer; 2014 Sep; 13():221. PubMed ID: 25253202
[TBL] [Abstract][Full Text] [Related]
18. Indolin-2-one compounds targeting thioredoxin reductase as potential anticancer drug leads.
Kaminska KK; Bertrand HC; Tajima H; Stafford WC; Cheng Q; Chen W; Wells G; Arner ES; Chew EH
Oncotarget; 2016 Jun; 7(26):40233-40251. PubMed ID: 27244886
[TBL] [Abstract][Full Text] [Related]
19. Molecular mechanism of apoptosis induction by Gaillardin, a sesquiterpene lactone, in breast cancer cell lines : Gaillardin-induced apoptosis in breast cancer cell lines.
Fallahian F; Aghaei M; Abdolmohammadi MH; Hamzeloo-Moghadam M
Cell Biol Toxicol; 2015 Dec; 31(6):295-305. PubMed ID: 26843455
[TBL] [Abstract][Full Text] [Related]
20. Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide.
Lu J; Chew EH; Holmgren A
Proc Natl Acad Sci U S A; 2007 Jul; 104(30):12288-93. PubMed ID: 17640917
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]