BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 26766588)

  • 1. Polycomb Repressive Complex 2 Is a Barrier to KRAS-Driven Inflammation and Epithelial-Mesenchymal Transition in Non-Small-Cell Lung Cancer.
    Serresi M; Gargiulo G; Proost N; Siteur B; Cesaroni M; Koppens M; Xie H; Sutherland KD; Hulsman D; Citterio E; Orkin S; Berns A; van Lohuizen M
    Cancer Cell; 2016 Jan; 29(1):17-31. PubMed ID: 26766588
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ezh2 Acts as a Tumor Suppressor in Kras-driven Lung Adenocarcinoma.
    Wang Y; Hou N; Cheng X; Zhang J; Tan X; Zhang C; Tang Y; Teng Y; Yang X
    Int J Biol Sci; 2017; 13(5):652-659. PubMed ID: 28539837
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ezh2 inhibition in Kras-driven lung cancer amplifies inflammation and associated vulnerabilities.
    Serresi M; Siteur B; Hulsman D; Company C; Schmitt MJ; Lieftink C; Morris B; Cesaroni M; Proost N; Beijersbergen RL; van Lohuizen M; Gargiulo G
    J Exp Med; 2018 Dec; 215(12):3115-3135. PubMed ID: 30487290
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutations and deletions of PRC2 in prostate cancer.
    Jain P; Di Croce L
    Bioessays; 2016 May; 38(5):446-54. PubMed ID: 27000413
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2.
    Zhang H; Fillmore Brainson C; Koyama S; Redig AJ; Chen T; Li S; Gupta M; Garcia-de-Alba C; Paschini M; Herter-Sprie GS; Lu G; Zhang X; Marsh BP; Tuminello SJ; Xu C; Chen Z; Wang X; Akbay EA; Zheng M; Palakurthi S; Sholl LM; Rustgi AK; Kwiatkowski DJ; Diehl JA; Bass AJ; Sharpless NE; Dranoff G; Hammerman PS; Ji H; Bardeesy N; Saur D; Watanabe H; Kim CF; Wong KK
    Nat Commun; 2017 Apr; 8():14922. PubMed ID: 28387316
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Deletion of Polycomb Repressive Complex 2 From Mouse Intestine Causes Loss of Stem Cells.
    Koppens MA; Bounova G; Gargiulo G; Tanger E; Janssen H; Cornelissen-Steijger P; Blom M; Song JY; Wessels LF; van Lohuizen M
    Gastroenterology; 2016 Oct; 151(4):684-697.e12. PubMed ID: 27342214
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chronic Cigarette Smoke-Induced Epigenomic Changes Precede Sensitization of Bronchial Epithelial Cells to Single-Step Transformation by KRAS Mutations.
    Vaz M; Hwang SY; Kagiampakis I; Phallen J; Patil A; O'Hagan HM; Murphy L; Zahnow CA; Gabrielson E; Velculescu VE; Easwaran HP; Baylin SB
    Cancer Cell; 2017 Sep; 32(3):360-376.e6. PubMed ID: 28898697
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Astemizole arrests the proliferation of cancer cells by disrupting the EZH2-EED interaction of polycomb repressive complex 2.
    Kong X; Chen L; Jiao L; Jiang X; Lian F; Lu J; Zhu K; Du D; Liu J; Ding H; Zhang N; Shen J; Zheng M; Chen K; Liu X; Jiang H; Luo C
    J Med Chem; 2014 Nov; 57(22):9512-21. PubMed ID: 25369470
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PCAF-primed EZH2 acetylation regulates its stability and promotes lung adenocarcinoma progression.
    Wan J; Zhan J; Li S; Ma J; Xu W; Liu C; Xue X; Xie Y; Fang W; Chin YE; Zhang H
    Nucleic Acids Res; 2015 Apr; 43(7):3591-604. PubMed ID: 25800736
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The polycomb group protein EZH2 inhibits lung cancer cell growth by repressing the transcription factor Nrf2.
    Li Z; Xu L; Tang N; Xu Y; Ye X; Shen S; Niu X; Lu S; Chen Z
    FEBS Lett; 2014 Aug; 588(17):3000-7. PubMed ID: 24928441
    [TBL] [Abstract][Full Text] [Related]  

  • 11. JARID2 is involved in transforming growth factor-beta-induced epithelial-mesenchymal transition of lung and colon cancer cell lines.
    Tange S; Oktyabri D; Terashima M; Ishimura A; Suzuki T
    PLoS One; 2014; 9(12):e115684. PubMed ID: 25542019
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Posttranscriptional silencing of the lncRNA MALAT1 by miR-217 inhibits the epithelial-mesenchymal transition via enhancer of zeste homolog 2 in the malignant transformation of HBE cells induced by cigarette smoke extract.
    Lu L; Luo F; Liu Y; Liu X; Shi L; Lu X; Liu Q
    Toxicol Appl Pharmacol; 2015 Dec; 289(2):276-85. PubMed ID: 26415832
    [TBL] [Abstract][Full Text] [Related]  

  • 13. EZH2 is regulated by ERK/AKT and targets integrin alpha2 gene to control Epithelial-Mesenchymal Transition and anoikis in colon cancer cells.
    Ferraro A; Mourtzoukou D; Kosmidou V; Avlonitis S; Kontogeorgos G; Zografos G; Pintzas A
    Int J Biochem Cell Biol; 2013 Feb; 45(2):243-54. PubMed ID: 23116973
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Polycomb deficiency drives a FOXP2-high aggressive state targetable by epigenetic inhibitors.
    Chen F; Byrd AL; Liu J; Flight RM; DuCote TJ; Naughton KJ; Song X; Edgin AR; Lukyanchuk A; Dixon DT; Gosser CM; Esoe DP; Jayswal RD; Orkin SH; Moseley HNB; Wang C; Brainson CF
    Nat Commun; 2023 Jan; 14(1):336. PubMed ID: 36670102
    [TBL] [Abstract][Full Text] [Related]  

  • 15. EED regulates epithelial-mesenchymal transition of cancer cells induced by TGF-β.
    Oktyabri D; Tange S; Terashima M; Ishimura A; Suzuki T
    Biochem Biophys Res Commun; 2014 Oct; 453(1):124-30. PubMed ID: 25264103
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Epigenetic silencing of p21 by long non-coding RNA HOTAIR is involved in the cell cycle disorder induced by cigarette smoke extract.
    Liu Y; Wang B; Liu X; Lu L; Luo F; Lu X; Shi L; Xu W; Liu Q
    Toxicol Lett; 2016 Jan; 240(1):60-7. PubMed ID: 26506537
    [TBL] [Abstract][Full Text] [Related]  

  • 17. EZH2 promotes tumor progression via regulating VEGF-A/AKT signaling in non-small cell lung cancer.
    Geng J; Li X; Zhou Z; Wu CL; Dai M; Bai X
    Cancer Lett; 2015 Apr; 359(2):275-87. PubMed ID: 25633838
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Loss of histone demethylase KDM6B enhances aggressiveness of pancreatic cancer through downregulation of C/EBPα.
    Yamamoto K; Tateishi K; Kudo Y; Sato T; Yamamoto S; Miyabayashi K; Matsusaka K; Asaoka Y; Ijichi H; Hirata Y; Otsuka M; Nakai Y; Isayama H; Ikenoue T; Kurokawa M; Fukayama M; Kokudo N; Omata M; Koike K
    Carcinogenesis; 2014 Nov; 35(11):2404-14. PubMed ID: 24947179
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Distinctive expression of the polycomb group proteins Bmi1 polycomb ring finger oncogene and enhancer of zeste homolog 2 in nonsmall cell lung cancers and their clinical and clinicopathologic significance.
    Kikuchi J; Kinoshita I; Shimizu Y; Kikuchi E; Konishi J; Oizumi S; Kaga K; Matsuno Y; Nishimura M; Dosaka-Akita H
    Cancer; 2010 Jun; 116(12):3015-24. PubMed ID: 20564407
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The polycomb group protein enhancer of zeste 2 is a novel therapeutic target for cervical cancer.
    Ding M; Zhang H; Li Z; Wang C; Chen J; Shi L; Xu D; Gao Y
    Clin Exp Pharmacol Physiol; 2015 May; 42(5):458-64. PubMed ID: 25739318
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.