BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

374 related articles for article (PubMed ID: 26769004)

  • 1. Inhibition of TGFβ signaling decreases osteogenic differentiation of fibrodysplasia ossificans progressiva fibroblasts in a novel in vitro model of the disease.
    Micha D; Voermans E; Eekhoff MEW; van Essen HW; Zandieh-Doulabi B; Netelenbos C; Rustemeyer T; Sistermans EA; Pals G; Bravenboer N
    Bone; 2016 Mar; 84():169-180. PubMed ID: 26769004
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The ACVR1 R206H mutation found in fibrodysplasia ossificans progressiva increases human induced pluripotent stem cell-derived endothelial cell formation and collagen production through BMP-mediated SMAD1/5/8 signaling.
    Barruet E; Morales BM; Lwin W; White MP; Theodoris CV; Kim H; Urrutia A; Wong SA; Srivastava D; Hsiao EC
    Stem Cell Res Ther; 2016 Aug; 7(1):115. PubMed ID: 27530160
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Periodontal ligament fibroblasts as a cell model to study osteogenesis and osteoclastogenesis in fibrodysplasia ossificans progressiva.
    de Vries TJ; Schoenmaker T; Micha D; Hogervorst J; Bouskla S; Forouzanfar T; Pals G; Netelenbos C; Eekhoff EMW; Bravenboer N
    Bone; 2018 Apr; 109():168-177. PubMed ID: 28705683
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TGF-Beta Induces Activin A Production in Dermal Fibroblasts Derived from Patients with Fibrodysplasia Ossificans Progressiva.
    de Ruiter RD; Wisse LE; Schoenmaker T; Yaqub M; Sánchez-Duffhues G; Eekhoff EMW; Micha D
    Int J Mol Sci; 2023 Jan; 24(3):. PubMed ID: 36768622
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dysregulated BMP signaling and enhanced osteogenic differentiation of connective tissue progenitor cells from patients with fibrodysplasia ossificans progressiva (FOP).
    Billings PC; Fiori JL; Bentwood JL; O'Connell MP; Jiao X; Nussbaum B; Caron RJ; Shore EM; Kaplan FS
    J Bone Miner Res; 2008 Mar; 23(3):305-13. PubMed ID: 17967130
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The effect of Activin-A on periodontal ligament fibroblasts-mediated osteoclast formation in healthy donors and in patients with fibrodysplasia ossificans progressiva.
    Schoenmaker T; Wouters F; Micha D; Forouzanfar T; Netelenbos C; Eekhoff EMW; Bravenboer N; de Vries TJ
    J Cell Physiol; 2019 Jul; 234(7):10238-10247. PubMed ID: 30417373
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Neofunction of ACVR1 in fibrodysplasia ossificans progressiva.
    Hino K; Ikeya M; Horigome K; Matsumoto Y; Ebise H; Nishio M; Sekiguchi K; Shibata M; Nagata S; Matsuda S; Toguchida J
    Proc Natl Acad Sci U S A; 2015 Dec; 112(50):15438-43. PubMed ID: 26621707
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Elevated BMP and Mechanical Signaling Through YAP1/RhoA Poises FOP Mesenchymal Progenitors for Osteogenesis.
    Stanley A; Heo SJ; Mauck RL; Mourkioti F; Shore EM
    J Bone Miner Res; 2019 Oct; 34(10):1894-1909. PubMed ID: 31107558
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of G
    Ebner JK; König GM; Kostenis E; Siegert P; Aktories K; Orth JHC
    Bone; 2019 Oct; 127():592-601. PubMed ID: 31376533
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular consequences of the ACVR1(R206H) mutation of fibrodysplasia ossificans progressiva.
    Song GA; Kim HJ; Woo KM; Baek JH; Kim GS; Choi JY; Ryoo HM
    J Biol Chem; 2010 Jul; 285(29):22542-53. PubMed ID: 20463014
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induced Pluripotent Stem Cells to Model Human Fibrodysplasia Ossificans Progressiva.
    Cai J; Orlova VV; Cai X; Eekhoff EMW; Zhang K; Pei D; Pan G; Mummery CL; Ten Dijke P
    Stem Cell Reports; 2015 Dec; 5(6):963-970. PubMed ID: 26626181
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ALK2 R206H mutation linked to fibrodysplasia ossificans progressiva confers constitutive activity to the BMP type I receptor and sensitizes mesenchymal cells to BMP-induced osteoblast differentiation and bone formation.
    van Dinther M; Visser N; de Gorter DJ; Doorn J; Goumans MJ; de Boer J; ten Dijke P
    J Bone Miner Res; 2010 Jun; 25(6):1208-15. PubMed ID: 19929436
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The obligatory role of Activin A in the formation of heterotopic bone in Fibrodysplasia Ossificans Progressiva.
    Alessi Wolken DM; Idone V; Hatsell SJ; Yu PB; Economides AN
    Bone; 2018 Apr; 109():210-217. PubMed ID: 28629737
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of osteoclasts in heterotopic ossification enhanced by fibrodysplasia ossificans progressiva-related activin-like kinase 2 mutation in mice.
    Kawao N; Yano M; Tamura Y; Okumoto K; Okada K; Kaji H
    J Bone Miner Metab; 2016 Sep; 34(5):517-25. PubMed ID: 26204847
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Allele-Selective LNA Gapmers for the Treatment of Fibrodysplasia Ossificans Progressiva Knock Down the Pathogenic ACVR1
    Maruyama R; Nguyen Q; Roshmi RR; Touznik A; Yokota T
    Nucleic Acid Ther; 2022 Jun; 32(3):185-193. PubMed ID: 35085461
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ACVR1-Fc suppresses BMP signaling and chondro-osseous differentiation in an in vitro model of Fibrodysplasia ossificans progressiva.
    Pang J; Zuo Y; Chen Y; Song L; Zhu Q; Yu J; Shan C; Cai Z; Hao J; Kaplan FS; Shore EM; Zhang K
    Bone; 2016 Nov; 92():29-36. PubMed ID: 27492611
    [TBL] [Abstract][Full Text] [Related]  

  • 17. High-throughput screening for modulators of ACVR1 transcription: discovery of potential therapeutics for fibrodysplasia ossificans progressiva.
    Cappato S; Tonachini L; Giacopelli F; Tirone M; Galietta LJ; Sormani M; Giovenzana A; Spinelli AE; Canciani B; Brunelli S; Ravazzolo R; Bocciardi R
    Dis Model Mech; 2016 Jun; 9(6):685-96. PubMed ID: 27125279
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Alk2 regulates early chondrogenic fate in fibrodysplasia ossificans progressiva heterotopic endochondral ossification.
    Culbert AL; Chakkalakal SA; Theosmy EG; Brennan TA; Kaplan FS; Shore EM
    Stem Cells; 2014 May; 32(5):1289-300. PubMed ID: 24449086
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Depletion of Mast Cells and Macrophages Impairs Heterotopic Ossification in an Acvr1
    Convente MR; Chakkalakal SA; Yang E; Caron RJ; Zhang D; Kambayashi T; Kaplan FS; Shore EM
    J Bone Miner Res; 2018 Feb; 33(2):269-282. PubMed ID: 28986986
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Palovarotene Inhibits Heterotopic Ossification and Maintains Limb Mobility and Growth in Mice With the Human ACVR1(R206H) Fibrodysplasia Ossificans Progressiva (FOP) Mutation.
    Chakkalakal SA; Uchibe K; Convente MR; Zhang D; Economides AN; Kaplan FS; Pacifici M; Iwamoto M; Shore EM
    J Bone Miner Res; 2016 Sep; 31(9):1666-75. PubMed ID: 26896819
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.