BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

599 related articles for article (PubMed ID: 26780455)

  • 1. TREM2 Overexpression has No Improvement on Neuropathology and Cognitive Impairment in Aging APPswe/PS1dE9 Mice.
    Jiang T; Wan Y; Zhang YD; Zhou JS; Gao Q; Zhu XC; Shi JQ; Lu H; Tan L; Yu JT
    Mol Neurobiol; 2017 Mar; 54(2):855-865. PubMed ID: 26780455
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Upregulation of TREM2 ameliorates neuropathology and rescues spatial cognitive impairment in a transgenic mouse model of Alzheimer's disease.
    Jiang T; Tan L; Zhu XC; Zhang QQ; Cao L; Tan MS; Gu LZ; Wang HF; Ding ZZ; Zhang YD; Yu JT
    Neuropsychopharmacology; 2014 Dec; 39(13):2949-62. PubMed ID: 25047746
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of Suppressor of Cytokine Signaling 3 (SOCS3) in Altering Activated Microglia Phenotype in APPswe/PS1dE9 Mice.
    Iwahara N; Hisahara S; Kawamata J; Matsumura A; Yokokawa K; Saito T; Fujikura M; Manabe T; Suzuki H; Matsushita T; Suzuki S; Shimohama S
    J Alzheimers Dis; 2017; 55(3):1235-1247. PubMed ID: 27814300
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TREM2 overexpression rescues cognitive deficits in APP/PS1 transgenic mice by reducing neuroinflammation via the JAK/STAT/SOCS signaling pathway.
    Ruganzu JB; Zheng Q; Wu X; He Y; Peng X; Jin H; Zhou J; Ma R; Ji S; Ma Y; Qian Y; Wang Y; Yang W
    Exp Neurol; 2021 Feb; 336():113506. PubMed ID: 33065077
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Upregulation of TREM2 Ameliorates Neuroinflammatory Responses and Improves Cognitive Deficits Triggered by Surgical Trauma in Appswe/PS1dE9 Mice.
    Jiang Y; Li Z; Ma H; Cao X; Liu F; Tian A; Sun X; Li X; Wang J
    Cell Physiol Biochem; 2018; 46(4):1398-1411. PubMed ID: 29689568
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Progressive Spatial Memory Impairment, Brain Amyloid Deposition and Changes in Serum Amyloid Levels as a Function of Age in APPswe/PS1dE9 Mice.
    Fu L; Sun Y; Guo Y; Yu B; Zhang H; Wu J; Yu X; Wu H; Kong W
    Curr Alzheimer Res; 2018; 15(11):1053-1061. PubMed ID: 29984654
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Morin reverses neuropathological and cognitive impairments in APPswe/PS1dE9 mice by targeting multiple pathogenic mechanisms.
    Du Y; Qu J; Zhang W; Bai M; Zhou Q; Zhang Z; Li Z; Miao J
    Neuropharmacology; 2016 Sep; 108():1-13. PubMed ID: 27067919
    [TBL] [Abstract][Full Text] [Related]  

  • 8. S14G-humanin improves cognitive deficits and reduces amyloid pathology in the middle-aged APPswe/PS1dE9 mice.
    Zhang W; Zhang W; Li Z; Hao J; Zhang Z; Liu L; Mao N; Miao J; Zhang L
    Pharmacol Biochem Behav; 2012 Jan; 100(3):361-9. PubMed ID: 21993310
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Microglial Trem2 induces synaptic impairment at early stage and prevents amyloidosis at late stage in APP/PS1 mice.
    Sheng L; Chen M; Cai K; Song Y; Yu D; Zhang H; Xu G
    FASEB J; 2019 Sep; 33(9):10425-10442. PubMed ID: 31219699
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Downregulation of TREM2 expression exacerbates neuroinflammatory responses through TLR4-mediated MAPK signaling pathway in a transgenic mouse model of Alzheimer's disease.
    Ruganzu JB; Peng X; He Y; Wu X; Zheng Q; Ding B; Lin C; Guo H; Yang Z; Zhang X; Yang W
    Mol Immunol; 2022 Feb; 142():22-36. PubMed ID: 34959070
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Soluble Aβ levels correlate with cognitive deficits in the 12-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease.
    Zhang W; Hao J; Liu R; Zhang Z; Lei G; Su C; Miao J; Li Z
    Behav Brain Res; 2011 Sep; 222(2):342-50. PubMed ID: 21513747
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TREM1 facilitates microglial phagocytosis of amyloid beta.
    Jiang T; Zhang YD; Gao Q; Zhou JS; Zhu XC; Lu H; Shi JQ; Tan L; Chen Q; Yu JT
    Acta Neuropathol; 2016 Nov; 132(5):667-683. PubMed ID: 27670763
    [TBL] [Abstract][Full Text] [Related]  

  • 13. TREM2 is upregulated in amyloid plaque-associated microglia in aged APP23 transgenic mice.
    Frank S; Burbach GJ; Bonin M; Walter M; Streit W; Bechmann I; Deller T
    Glia; 2008 Oct; 56(13):1438-47. PubMed ID: 18551625
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TREM2 modifies microglial phenotype and provides neuroprotection in P301S tau transgenic mice.
    Jiang T; Zhang YD; Chen Q; Gao Q; Zhu XC; Zhou JS; Shi JQ; Lu H; Tan L; Yu JT
    Neuropharmacology; 2016 Jun; 105():196-206. PubMed ID: 26802771
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Loss of TREM2 Confers Resilience to Synaptic and Cognitive Impairment in Aged Mice.
    Qu W; Li L
    J Neurosci; 2020 Dec; 40(50):9552-9563. PubMed ID: 33139402
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression Profiling of Cytokine, Cholinergic Markers, and Amyloid-β Deposition in the APPSWE/PS1dE9 Mouse Model of Alzheimer's Disease Pathology.
    Reale M; D'Angelo C; Costantini E; Di Nicola M; Yarla NS; Kamal MA; Salvador N; Perry G
    J Alzheimers Dis; 2018; 62(1):467-476. PubMed ID: 29439355
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities.
    Savonenko A; Xu GM; Melnikova T; Morton JL; Gonzales V; Wong MP; Price DL; Tang F; Markowska AL; Borchelt DR
    Neurobiol Dis; 2005 Apr; 18(3):602-17. PubMed ID: 15755686
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hippocampal administration of chondroitinase ABC increases plaque-adjacent synaptic marker and diminishes amyloid burden in aged APPswe/PS1dE9 mice.
    Howell MD; Bailey LA; Cozart MA; Gannon BM; Gottschall PE
    Acta Neuropathol Commun; 2015 Sep; 3():54. PubMed ID: 26337292
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Multiple inflammatory pathways are involved in the development and progression of cognitive deficits in APPswe/PS1dE9 mice.
    Zhang W; Bai M; Xi Y; Hao J; Zhang Z; Su C; Lei G; Miao J; Li Z
    Neurobiol Aging; 2012 Nov; 33(11):2661-77. PubMed ID: 22277264
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease.
    Melchior B; Garcia AE; Hsiung BK; Lo KM; Doose JM; Thrash JC; Stalder AK; Staufenbiel M; Neumann H; Carson MJ
    ASN Neuro; 2010 Jul; 2(3):e00037. PubMed ID: 20640189
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.