BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

410 related articles for article (PubMed ID: 26781224)

  • 21. Coordination of the leucine-sensing Rag GTPase cycle by leucyl-tRNA synthetase in the mTORC1 signaling pathway.
    Lee M; Kim JH; Yoon I; Lee C; Fallahi Sichani M; Kang JS; Kang J; Guo M; Lee KY; Han G; Kim S; Han JM
    Proc Natl Acad Sci U S A; 2018 Jun; 115(23):E5279-E5288. PubMed ID: 29784813
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Amino Acid- and Insulin-Induced Activation of mTORC1 in Neonatal Piglet Skeletal Muscle Involves Sestin2-GATOR2, Rag A/C-mTOR, and RHEB-mTOR Complex Formation.
    Suryawan A; Davis TA
    J Nutr; 2018 Jun; 148(6):825-833. PubMed ID: 29796625
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Regulation of TORC1 in response to amino acid starvation via lysosomal recruitment of TSC2.
    Demetriades C; Doumpas N; Teleman AA
    Cell; 2014 Feb; 156(4):786-99. PubMed ID: 24529380
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Rheb and Rags come together at the lysosome to activate mTORC1.
    Groenewoud MJ; Zwartkruis FJ
    Biochem Soc Trans; 2013 Aug; 41(4):951-5. PubMed ID: 23863162
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Amino acid-dependent NPRL2 interaction with Raptor determines mTOR Complex 1 activation.
    Kwak SS; Kang KH; Kim S; Lee S; Lee JH; Kim JW; Byun B; Meadows GG; Joe CO
    Cell Signal; 2016 Feb; 28(2):32-41. PubMed ID: 26582740
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Regulation of mTORC1 by the Rag GTPases.
    Lama-Sherpa TD; Jeong MH; Jewell JL
    Biochem Soc Trans; 2023 Apr; 51(2):655-664. PubMed ID: 36929165
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Re-evaluating the roles of proposed modulators of mammalian target of rapamycin complex 1 (mTORC1) signaling.
    Wang X; Fonseca BD; Tang H; Liu R; Elia A; Clemens MJ; Bommer UA; Proud CG
    J Biol Chem; 2008 Nov; 283(45):30482-92. PubMed ID: 18676370
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity.
    Yao Y; Hong S; Ikeda T; Mori H; MacDougald OA; Nada S; Okada M; Inoki K
    Mol Cell; 2020 Nov; 80(3):437-451.e6. PubMed ID: 33157014
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Redundant electrostatic interactions between GATOR1 and the Rag GTPase heterodimer drive efficient amino acid sensing in human cells.
    Doxsey DD; Tettoni SD; Egri SB; Shen K
    J Biol Chem; 2023 Jul; 299(7):104880. PubMed ID: 37269949
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Rag GTPases are cardioprotective by regulating lysosomal function.
    Kim YC; Park HW; Sciarretta S; Mo JS; Jewell JL; Russell RC; Wu X; Sadoshima J; Guan KL
    Nat Commun; 2014 Jul; 5():4241. PubMed ID: 24980141
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival.
    Efeyan A; Zoncu R; Chang S; Gumper I; Snitkin H; Wolfson RL; Kirak O; Sabatini DD; Sabatini DM
    Nature; 2013 Jan; 493(7434):679-83. PubMed ID: 23263183
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.
    Wang S; Tsun ZY; Wolfson RL; Shen K; Wyant GA; Plovanich ME; Yuan ED; Jones TD; Chantranupong L; Comb W; Wang T; Bar-Peled L; Zoncu R; Straub C; Kim C; Park J; Sabatini BL; Sabatini DM
    Science; 2015 Jan; 347(6218):188-94. PubMed ID: 25567906
    [TBL] [Abstract][Full Text] [Related]  

  • 33. mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase.
    Zoncu R; Bar-Peled L; Efeyan A; Wang S; Sancak Y; Sabatini DM
    Science; 2011 Nov; 334(6056):678-83. PubMed ID: 22053050
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Lysosomal accumulation of mTOR is enhanced by rapamycin.
    Ohsaki Y; Suzuki M; Shinohara Y; Fujimoto T
    Histochem Cell Biol; 2010 Dec; 134(6):537-44. PubMed ID: 21063721
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex.
    Cui Z; Napolitano G; de Araujo MEG; Esposito A; Monfregola J; Huber LA; Ballabio A; Hurley JH
    Nature; 2023 Feb; 614(7948):572-579. PubMed ID: 36697823
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Dynamin-dependent amino acid endocytosis activates mechanistic target of rapamycin complex 1 (mTORC1).
    Shibutani S; Okazaki H; Iwata H
    J Biol Chem; 2017 Nov; 292(44):18052-18061. PubMed ID: 28808055
    [TBL] [Abstract][Full Text] [Related]  

  • 37. MCRS1 binds and couples Rheb to amino acid-dependent mTORC1 activation.
    Fawal MA; Brandt M; Djouder N
    Dev Cell; 2015 Apr; 33(1):67-81. PubMed ID: 25816988
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Regulation of mTORC1 by amino acids.
    Bar-Peled L; Sabatini DM
    Trends Cell Biol; 2014 Jul; 24(7):400-6. PubMed ID: 24698685
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Rags to riches: Amino acid sensing by the Rag GTPases in health and disease.
    Brady OA; Diab HI; Puertollano R
    Small GTPases; 2016 Oct; 7(4):197-206. PubMed ID: 27580159
    [TBL] [Abstract][Full Text] [Related]  

  • 40. RagA, an mTORC1 activator, interacts with a hedgehog signaling protein, WDR35/IFT121.
    Sekiguchi T; Furuno N; Ishii T; Hirose E; Sekiguchi F; Wang Y; Kobayashi H
    Genes Cells; 2019 Feb; 24(2):151-161. PubMed ID: 30570184
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 21.