BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

261 related articles for article (PubMed ID: 26781748)

  • 1. Multi-omic measurement of mutually exclusive loss-of-function enriches for candidate synthetic lethal gene pairs.
    Wappett M; Dulak A; Yang ZR; Al-Watban A; Bradford JR; Dry JR
    BMC Genomics; 2016 Jan; 17():65. PubMed ID: 26781748
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Integrated genomic and pharmacological approaches to identify synthetic lethal genes as cancer therapeutic targets.
    Mizuarai S; Irie H; Schmatz DM; Kotani H
    Curr Mol Med; 2008 Dec; 8(8):774-83. PubMed ID: 19075675
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DiscoverSL: an R package for multi-omic data driven prediction of synthetic lethality in cancers.
    Das S; Deng X; Camphausen K; Shankavaram U
    Bioinformatics; 2019 Feb; 35(4):701-702. PubMed ID: 30059974
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inferring synthetic lethal interactions from mutual exclusivity of genetic events in cancer.
    Srihari S; Singla J; Wong L; Ragan MA
    Biol Direct; 2015 Oct; 10():57. PubMed ID: 26427375
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Using pooled miR30-shRNA library for cancer lethal and synthetic lethal screens.
    Lee LC; Gao S; Li Q; Luo J
    Methods Mol Biol; 2014; 1176():45-58. PubMed ID: 25030918
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Malignancy of Cancers and Synthetic Lethal Interactions Associated With Mutations of Cancer Driver Genes.
    Wang X; Zhang Y; Han ZG; He KY
    Medicine (Baltimore); 2016 Feb; 95(8):e2697. PubMed ID: 26937901
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of potential synthetic lethal genes to p53 using a computational biology approach.
    Wang X; Simon R
    BMC Med Genomics; 2013 Sep; 6():30. PubMed ID: 24025726
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthetic lethal interactions for the development of cancer therapeutics: biological and methodological advancements.
    Mizuarai S; Kotani H
    Hum Genet; 2010 Dec; 128(6):567-75. PubMed ID: 20976469
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ranking novel cancer driving synthetic lethal gene pairs using TCGA data.
    Ye H; Zhang X; Chen Y; Liu Q; Wei J
    Oncotarget; 2016 Aug; 7(34):55352-55367. PubMed ID: 27438146
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Integrative analysis of large-scale loss-of-function screens identifies robust cancer-associated genetic interactions.
    Lord CJ; Quinn N; Ryan CJ
    Elife; 2020 May; 9():. PubMed ID: 32463358
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of synthetic lethal and tumor suppressor paralog pairs in the human genome.
    Parrish PCR; Thomas JD; Gabel AM; Kamlapurkar S; Bradley RK; Berger AH
    Cell Rep; 2021 Aug; 36(9):109597. PubMed ID: 34469736
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Overcoming selection bias in synthetic lethality prediction.
    Seale C; Tepeli Y; Gonçalves JP
    Bioinformatics; 2022 Sep; 38(18):4360-4368. PubMed ID: 35876858
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthetic lethal genetic screens in Ras mutant cancers.
    Yu B; Luo J
    Enzymes; 2013; 34 Pt. B():201-19. PubMed ID: 25034106
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Leveraging synthetic lethality to uncover potential therapeutic target in gastric cancer.
    Geng H; Qian R; Zhong Y; Tang X; Zhang X; Zhang L; Yang C; Li T; Dong Z; Wang C; Zhang Z; Zhu C
    Cancer Gene Ther; 2024 Feb; 31(2):334-348. PubMed ID: 38040871
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening.
    McDonald ER; de Weck A; Schlabach MR; Billy E; Mavrakis KJ; Hoffman GR; Belur D; Castelletti D; Frias E; Gampa K; Golji J; Kao I; Li L; Megel P; Perkins TA; Ramadan N; Ruddy DA; Silver SJ; Sovath S; Stump M; Weber O; Widmer R; Yu J; Yu K; Yue Y; Abramowski D; Ackley E; Barrett R; Berger J; Bernard JL; Billig R; Brachmann SM; Buxton F; Caothien R; Caushi JX; Chung FS; Cortés-Cros M; deBeaumont RS; Delaunay C; Desplat A; Duong W; Dwoske DA; Eldridge RS; Farsidjani A; Feng F; Feng J; Flemming D; Forrester W; Galli GG; Gao Z; Gauter F; Gibaja V; Haas K; Hattenberger M; Hood T; Hurov KE; Jagani Z; Jenal M; Johnson JA; Jones MD; Kapoor A; Korn J; Liu J; Liu Q; Liu S; Liu Y; Loo AT; Macchi KJ; Martin T; McAllister G; Meyer A; Mollé S; Pagliarini RA; Phadke T; Repko B; Schouwey T; Shanahan F; Shen Q; Stamm C; Stephan C; Stucke VM; Tiedt R; Varadarajan M; Venkatesan K; Vitari AC; Wallroth M; Weiler J; Zhang J; Mickanin C; Myer VE; Porter JA; Lai A; Bitter H; Lees E; Keen N; Kauffmann A; Stegmeier F; Hofmann F; Schmelzle T; Sellers WR
    Cell; 2017 Jul; 170(3):577-592.e10. PubMed ID: 28753431
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthetic sickness or lethality points at candidate combination therapy targets in glioblastoma.
    Szczurek E; Misra N; Vingron M
    Int J Cancer; 2013 Nov; 133(9):2123-32. PubMed ID: 23629686
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Exploration of synthetic lethal interactions as cancer drug targets.
    Kuiken HJ; Beijersbergen RL
    Future Oncol; 2010 Nov; 6(11):1789-802. PubMed ID: 21142664
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genetic Interaction Motif Finding by expectation maximization--a novel statistical model for inferring gene modules from synthetic lethality.
    Qi Y; Ye P; Bader JS
    BMC Bioinformatics; 2005 Dec; 6():288. PubMed ID: 16332255
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium.
    Lerman MI; Minna JD
    Cancer Res; 2000 Nov; 60(21):6116-33. PubMed ID: 11085536
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SynLethDB: synthetic lethality database toward discovery of selective and sensitive anticancer drug targets.
    Guo J; Liu H; Zheng J
    Nucleic Acids Res; 2016 Jan; 44(D1):D1011-7. PubMed ID: 26516187
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.