BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 26783998)

  • 1. DOT1L histone methyltransferase regulates the expression of BCAT1 and is involved in sphere formation and cell migration of breast cancer cell lines.
    Oktyabri D; Ishimura A; Tange S; Terashima M; Suzuki T
    Biochimie; 2016 Apr; 123():20-31. PubMed ID: 26783998
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation of Wnt signaling target gene expression by the histone methyltransferase DOT1L.
    Gibbons GS; Owens SR; Fearon ER; Nikolovska-Coleska Z
    ACS Chem Biol; 2015 Jan; 10(1):109-14. PubMed ID: 25361163
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Deficiency of H3K79 histone methyltransferase Dot1-like protein (DOT1L) inhibits cell proliferation.
    Kim W; Kim R; Park G; Park JW; Kim JE
    J Biol Chem; 2012 Feb; 287(8):5588-99. PubMed ID: 22190683
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Prognostic and therapeutic value of disruptor of telomeric silencing-1-like (DOT1L) expression in patients with ovarian cancer.
    Zhang X; Liu D; Li M; Cao C; Wan D; Xi B; Li W; Tan J; Wang J; Wu Z; Ma D; Gao Q
    J Hematol Oncol; 2017 Jan; 10(1):29. PubMed ID: 28114995
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Histone Methyltransferase DOT1L Promotes Neuroblastoma by Regulating Gene Transcription.
    Wong M; Tee AEL; Milazzo G; Bell JL; Poulos RC; Atmadibrata B; Sun Y; Jing D; Ho N; Ling D; Liu PY; Zhang XD; Hüttelmaier S; Wong JWH; Wang J; Polly P; Perini G; Scarlett CJ; Liu T
    Cancer Res; 2017 May; 77(9):2522-2533. PubMed ID: 28209620
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dot1L mediated histone H3 lysine79 methylation is essential to meiosis progression in mouse oocytes.
    Wang X; Gao W; Ma X; Wang X; Song C; Huang X; Liu H
    Neuro Endocrinol Lett; 2014; 35(6):523-30. PubMed ID: 25433842
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The histone methyltransferase Dot1/DOT1L as a critical regulator of the cell cycle.
    Kim W; Choi M; Kim JE
    Cell Cycle; 2014; 13(5):726-38. PubMed ID: 24526115
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Branched-chain amino acid transaminase 1 (BCAT1) promotes the growth of breast cancer cells through improving mTOR-mediated mitochondrial biogenesis and function.
    Zhang L; Han J
    Biochem Biophys Res Commun; 2017 Apr; 486(2):224-231. PubMed ID: 28235484
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DOT1L Activity Promotes Proliferation and Protects Cortical Neural Stem Cells from Activation of ATF4-DDIT3-Mediated ER Stress In Vitro.
    Roidl D; Hellbach N; Bovio PP; Villarreal A; Heidrich S; Nestel S; Grüning BA; Boenisch U; Vogel T
    Stem Cells; 2016 Jan; 34(1):233-45. PubMed ID: 26299268
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DOT1L cooperates with the c-Myc-p300 complex to epigenetically derepress CDH1 transcription factors in breast cancer progression.
    Cho MH; Park JH; Choi HJ; Park MK; Won HY; Park YJ; Lee CH; Oh SH; Song YS; Kim HS; Oh YH; Lee JY; Kong G
    Nat Commun; 2015 Jul; 6():7821. PubMed ID: 26199140
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of histone H3K79 methylation selectively inhibits proliferation, self-renewal and metastatic potential of breast cancer.
    Zhang L; Deng L; Chen F; Yao Y; Wu B; Wei L; Mo Q; Song Y
    Oncotarget; 2014 Nov; 5(21):10665-77. PubMed ID: 25359765
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor.
    FitzGerald J; Moureau S; Drogaris P; O'Connell E; Abshiru N; Verreault A; Thibault P; Grenon M; Lowndes NF
    PLoS One; 2011 Feb; 6(2):e14714. PubMed ID: 21383990
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells.
    Steger DJ; Lefterova MI; Ying L; Stonestrom AJ; Schupp M; Zhuo D; Vakoc AL; Kim JE; Chen J; Lazar MA; Blobel GA; Vakoc CR
    Mol Cell Biol; 2008 Apr; 28(8):2825-39. PubMed ID: 18285465
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The upstreams and downstreams of H3K79 methylation by DOT1L.
    Vlaming H; van Leeuwen F
    Chromosoma; 2016 Sep; 125(4):593-605. PubMed ID: 26728620
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential Methylation of H3K79 Reveals DOT1L Target Genes and Function in the Cerebellum In Vivo.
    Bovio PP; Franz H; Heidrich S; Rauleac T; Kilpert F; Manke T; Vogel T
    Mol Neurobiol; 2019 Jun; 56(6):4273-4287. PubMed ID: 30302725
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
    Chen S; Yang Z; Wilkinson AW; Deshpande AJ; Sidoli S; Krajewski K; Strahl BD; Garcia BA; Armstrong SA; Patel DJ; Gozani O
    Mol Cell; 2015 Oct; 60(2):319-27. PubMed ID: 26439302
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeting Histone Methyltransferase DOT1L by a Novel Psammaplin A Analog Inhibits Growth and Metastasis of Triple-Negative Breast Cancer.
    Byun WS; Kim WK; Han HJ; Chung HJ; Jang K; Kim HS; Kim S; Kim D; Bae ES; Park S; Lee J; Park HG; Lee SK
    Mol Ther Oncolytics; 2019 Dec; 15():140-152. PubMed ID: 31720371
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The emerging roles of DOT1L in leukemia and normal development.
    McLean CM; Karemaker ID; van Leeuwen F
    Leukemia; 2014 Nov; 28(11):2131-8. PubMed ID: 24854991
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.
    Chen CW; Koche RP; Sinha AU; Deshpande AJ; Zhu N; Eng R; Doench JG; Xu H; Chu SH; Qi J; Wang X; Delaney C; Bernt KM; Root DE; Hahn WC; Bradner JE; Armstrong SA
    Nat Med; 2015 Apr; 21(4):335-43. PubMed ID: 25822366
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DOT1L-mediated H3K79 methylation in chromatin is dispensable for Wnt pathway-specific and other intestinal epithelial functions.
    Ho LL; Sinha A; Verzi M; Bernt KM; Armstrong SA; Shivdasani RA
    Mol Cell Biol; 2013 May; 33(9):1735-45. PubMed ID: 23428873
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.