BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

530 related articles for article (PubMed ID: 26784250)

  • 21. DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS.
    Lauth M; Bergström A; Shimokawa T; Tostar U; Jin Q; Fendrich V; Guerra C; Barbacid M; Toftgård R
    Nat Struct Mol Biol; 2010 Jun; 17(6):718-25. PubMed ID: 20512148
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Hedgehog signaling is a novel therapeutic target in tamoxifen-resistant breast cancer aberrantly activated by PI3K/AKT pathway.
    Ramaswamy B; Lu Y; Teng KY; Nuovo G; Li X; Shapiro CL; Majumder S
    Cancer Res; 2012 Oct; 72(19):5048-59. PubMed ID: 22875023
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Expression profile of sonic hedgehog signaling-related molecules in basal cell carcinoma.
    Kim HS; Kim YS; Lee C; Shin MS; Kim JW; Jang BG
    PLoS One; 2019; 14(11):e0225511. PubMed ID: 31756206
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Hedgehog-GLI signaling inhibition suppresses tumor growth in squamous lung cancer.
    Huang L; Walter V; Hayes DN; Onaitis M
    Clin Cancer Res; 2014 Mar; 20(6):1566-75. PubMed ID: 24423612
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Gli as a novel therapeutic target in malignant pleural mesothelioma.
    Li H; Lui N; Cheng T; Tseng HH; Yue D; Giroux-Leprieur E; Do HT; Sheng Q; Jin JQ; Luh TW; Jablons DM; He B
    PLoS One; 2013; 8(3):e57346. PubMed ID: 23483902
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe.
    Pietrobono S; Santini R; Gagliardi S; Dapporto F; Colecchia D; Chiariello M; Leone C; Valoti M; Manetti F; Petricci E; Taddei M; Stecca B
    Cell Death Dis; 2018 Feb; 9(2):142. PubMed ID: 29396391
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Protein kinase A activation inhibits oncogenic Sonic hedgehog signalling and suppresses basal cell carcinoma of the skin.
    Makinodan E; Marneros AG
    Exp Dermatol; 2012 Nov; 21(11):847-52. PubMed ID: 23163650
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Casein Kinase 1D Encodes a Novel Drug Target in Hedgehog-GLI-Driven Cancers and Tumor-Initiating Cells Resistant to SMO Inhibition.
    Peer E; Aichberger SK; Vilotic F; Gruber W; Parigger T; Grund-Gröschke S; Elmer DP; Rathje F; Ramspacher A; Zaja M; Michel S; Hamm S; Aberger F
    Cancers (Basel); 2021 Aug; 13(16):. PubMed ID: 34439381
    [TBL] [Abstract][Full Text] [Related]  

  • 29. LKB1 inhibits breast cancer partially through repressing the Hedgehog signaling pathway.
    Zhuang Z; Wang K; Cheng X; Qu X; Jiang B; Li Z; Luo J; Shao Z; Duan T
    PLoS One; 2013; 8(7):e67431. PubMed ID: 23861764
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers.
    Long J; Li B; Rodriguez-Blanco J; Pastori C; Volmar CH; Wahlestedt C; Capobianco A; Bai F; Pei XH; Ayad NG; Robbins DJ
    J Biol Chem; 2014 Dec; 289(51):35494-502. PubMed ID: 25355313
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Small Molecule Inhibitors of the Hedgehog Pathway in the Treatment of Basal Cell Carcinoma of the Skin.
    Danhof R; Lewis K; Brown M
    Am J Clin Dermatol; 2018 Apr; 19(2):195-207. PubMed ID: 28887802
    [TBL] [Abstract][Full Text] [Related]  

  • 32. ABT-737 suppresses aberrant Hedgehog pathway and overcomes resistance to smoothened antagonists by blocking Gli.
    Huang W; Liu H; Tan W; Wang J
    Med Oncol; 2022 Sep; 39(12):188. PubMed ID: 36071246
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Targeting Hedgehog Pathway and DNA Methyltransferases in Uterine Leiomyosarcoma Cells.
    Garcia N; Al-Hendy A; Baracat EC; Carvalho KC; Yang Q
    Cells; 2020 Dec; 10(1):. PubMed ID: 33396427
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Hedgehog Signaling and Truncated GLI1 in Cancer.
    Doheny D; Manore SG; Wong GL; Lo HW
    Cells; 2020 Sep; 9(9):. PubMed ID: 32957513
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Targeting the Hedgehog pathway with novel Gli1 hydrophobic tagging degraders.
    Li X; Sun R; Wu H; Zheng C; Long YQ
    Bioorg Chem; 2023 Sep; 138():106649. PubMed ID: 37307715
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Novel-smoothened inhibitors for therapeutic targeting of naïve and drug-resistant hedgehog pathway-driven cancers.
    Li QR; Zhao H; Zhang XS; Lang H; Yu K
    Acta Pharmacol Sin; 2019 Feb; 40(2):257-267. PubMed ID: 29777201
    [TBL] [Abstract][Full Text] [Related]  

  • 37. A polymeric nanoparticle encapsulated small-molecule inhibitor of Hedgehog signaling (NanoHHI) bypasses secondary mutational resistance to Smoothened antagonists.
    Chenna V; Hu C; Pramanik D; Aftab BT; Karikari C; Campbell NR; Hong SM; Zhao M; Rudek MA; Khan SR; Rudin CM; Maitra A
    Mol Cancer Ther; 2012 Jan; 11(1):165-73. PubMed ID: 22027695
    [TBL] [Abstract][Full Text] [Related]  

  • 38. GPCR-like signaling mediated by smoothened contributes to acquired chemoresistance through activating Gli.
    Zhan X; Wang J; Liu Y; Peng Y; Tan W
    Mol Cancer; 2014 Jan; 13():4. PubMed ID: 24393163
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Gli promotes epithelial-mesenchymal transition in human lung adenocarcinomas.
    Li H; Yue D; Jin JQ; Woodard GA; Tolani B; Luh TM; Giroux-Leprieur E; Mo M; Chen Z; Che J; Zhang Z; Zhou Y; Wang L; Hao X; Jablons D; Wang C; He B
    Oncotarget; 2016 Dec; 7(49):80415-80425. PubMed ID: 27533453
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Hedgehog-signaling is upregulated in non-producing human adrenal adenomas and antagonism of hedgehog-signaling inhibits proliferation of NCI-H295R cells and an immortalized primary human adrenal cell line.
    Werminghaus P; Haase M; Hornsby PJ; Schinner S; Schott M; Malendowicz LK; Lammers BJ; Goretzki PE; Müller-Mattheis V; Markus Giessing ; Willenberg HS
    J Steroid Biochem Mol Biol; 2014 Jan; 139():7-15. PubMed ID: 24063979
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 27.