BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

243 related articles for article (PubMed ID: 26792861)

  • 1. Transcriptional Regulation of X-Box-binding Protein One (XBP1) by Hepatocyte Nuclear Factor 4α (HNF4Α) Is Vital to Beta-cell Function.
    Moore BD; Jin RU; Lo H; Jung M; Wang H; Battle MA; Wollheim CB; Urano F; Mills JC
    J Biol Chem; 2016 Mar; 291(12):6146-57. PubMed ID: 26792861
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hepatic nuclear factor 1alpha (HNF1alpha) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes beta-cells to endoplasmic reticulum stress.
    Kirkpatrick CL; Wiederkehr A; Baquié M; Akhmedov D; Wang H; Gauthier BR; Akerman I; Ishihara H; Ferrer J; Wollheim CB
    J Biol Chem; 2011 Sep; 286(37):32300-12. PubMed ID: 21784843
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hepatocyte nuclear factor 4α is required for cell differentiation and homeostasis in the adult mouse gastric epithelium.
    Moore BD; Khurana SS; Huh WJ; Mills JC
    Am J Physiol Gastrointest Liver Physiol; 2016 Aug; 311(2):G267-75. PubMed ID: 27340127
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ErbB3-binding protein 1 (EBP1) represses HNF4α-mediated transcription and insulin secretion in pancreatic β-cells.
    Han EH; Singh P; Lee IK; Urrutia R; Chi YI
    J Biol Chem; 2019 Sep; 294(38):13983-13994. PubMed ID: 31362984
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sustained production of spliced X-box binding protein 1 (XBP1) induces pancreatic beta cell dysfunction and apoptosis.
    Allagnat F; Christulia F; Ortis F; Pirot P; Lortz S; Lenzen S; Eizirik DL; Cardozo AK
    Diabetologia; 2010 Jun; 53(6):1120-30. PubMed ID: 20349222
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients.
    Marchetti P; Bugliani M; Lupi R; Marselli L; Masini M; Boggi U; Filipponi F; Weir GC; Eizirik DL; Cnop M
    Diabetologia; 2007 Dec; 50(12):2486-94. PubMed ID: 17906960
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hepatocyte nuclear factor 4alpha regulates the expression of pancreatic beta -cell genes implicated in glucose metabolism and nutrient-induced insulin secretion.
    Wang H; Maechler P; Antinozzi PA; Hagenfeldt KA; Wollheim CB
    J Biol Chem; 2000 Nov; 275(46):35953-9. PubMed ID: 10967120
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Maturity-onset diabetes of the young Type 1 (MODY1)-associated mutations R154X and E276Q in hepatocyte nuclear factor 4alpha (HNF4alpha) gene impair recruitment of p300, a key transcriptional co-activator.
    Eeckhoute J; Formstecher P; Laine B
    Mol Endocrinol; 2001 Jul; 15(7):1200-10. PubMed ID: 11435618
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hepatocyte nuclear factor-4alpha involved in type 1 maturity-onset diabetes of the young is a novel target of AMP-activated protein kinase.
    Leclerc I; Lenzner C; Gourdon L; Vaulont S; Kahn A; Viollet B
    Diabetes; 2001 Jul; 50(7):1515-21. PubMed ID: 11423471
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutations in hepatocyte nuclear factor 4alpha (HNF4alpha) gene associated with diabetes result in greater loss of HNF4alpha function in pancreatic beta-cells than in nonpancreatic beta-cells and in reduced activation of the apolipoprotein CIII promoter in hepatic cells.
    Oxombre B; Moerman E; Eeckhoute J; Formstecher P; Laine B
    J Mol Med (Berl); 2002 Jul; 80(7):423-30. PubMed ID: 12110948
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Genetic evidence that HNF-1alpha-dependent transcriptional control of HNF-4alpha is essential for human pancreatic beta cell function.
    Hansen SK; Párrizas M; Jensen ML; Pruhova S; Ek J; Boj SF; Johansen A; Maestro MA; Rivera F; Eiberg H; Andel M; Lebl J; Pedersen O; Ferrer J; Hansen T
    J Clin Invest; 2002 Sep; 110(6):827-33. PubMed ID: 12235114
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Roles of HNF1α and HNF4α in pancreatic β-cells: lessons from a monogenic form of diabetes (MODY).
    Yamagata K
    Vitam Horm; 2014; 95():407-23. PubMed ID: 24559927
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The endoplasmic reticulum stress response is stimulated through the continuous activation of transcription factors ATF6 and XBP1 in Ins2+/Akita pancreatic beta cells.
    Nozaki Ji; Kubota H; Yoshida H; Naitoh M; Goji J; Yoshinaga T; Mori K; Koizumi A; Nagata K
    Genes Cells; 2004 Mar; 9(3):261-70. PubMed ID: 15005713
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The balance between adaptive and apoptotic unfolded protein responses regulates β-cell death under ER stress conditions through XBP1, CHOP and JNK.
    Chan JY; Luzuriaga J; Maxwell EL; West PK; Bensellam M; Laybutt DR
    Mol Cell Endocrinol; 2015 Sep; 413():189-201. PubMed ID: 26135354
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The MODY1 gene HNF-4alpha regulates selected genes involved in insulin secretion.
    Gupta RK; Vatamaniuk MZ; Lee CS; Flaschen RC; Fulmer JT; Matschinsky FM; Duncan SA; Kaestner KH
    J Clin Invest; 2005 Apr; 115(4):1006-15. PubMed ID: 15761495
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Preconditioning with endoplasmic reticulum stress mitigates retinal endothelial inflammation via activation of X-box binding protein 1.
    Li J; Wang JJ; Zhang SX
    J Biol Chem; 2011 Feb; 286(6):4912-21. PubMed ID: 21138840
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MED25 is a mediator component of HNF4α-driven transcription leading to insulin secretion in pancreatic beta-cells.
    Han EH; Rha GB; Chi YI
    PLoS One; 2012; 7(8):e44007. PubMed ID: 22952853
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel mechanisms of regulation of the expression and transcriptional activity of hepatocyte nuclear factor 4α.
    Guo S; Lu H
    J Cell Biochem; 2019 Jan; 120(1):519-532. PubMed ID: 30191603
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism.
    Stoffel M; Duncan SA
    Proc Natl Acad Sci U S A; 1997 Nov; 94(24):13209-14. PubMed ID: 9371825
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The integrated endoplasmic reticulum stress response in Leishmania amazonensis macrophage infection: the role of X-box binding protein 1 transcription factor.
    Dias-Teixeira KL; Calegari-Silva TC; dos Santos GR; Vitorino Dos Santos J; Lima C; Medina JM; Aktas BH; Lopes UG
    FASEB J; 2016 Apr; 30(4):1557-65. PubMed ID: 26678450
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.