373 related articles for article (PubMed ID: 26792955)
1. Targeting Th17 Cells with Small Molecules and Small Interference RNA.
Lin H; Song P; Zhao Y; Xue LJ; Liu Y; Chu CQ
Mediators Inflamm; 2015; 2015():290657. PubMed ID: 26792955
[TBL] [Abstract][Full Text] [Related]
2. Targeting Th17 cells in autoimmune diseases.
Yang J; Sundrud MS; Skepner J; Yamagata T
Trends Pharmacol Sci; 2014 Oct; 35(10):493-500. PubMed ID: 25131183
[TBL] [Abstract][Full Text] [Related]
3. Pharmacologic inhibition of RORγt regulates Th17 signature gene expression and suppresses cutaneous inflammation in vivo.
Skepner J; Ramesh R; Trocha M; Schmidt D; Baloglu E; Lobera M; Carlson T; Hill J; Orband-Miller LA; Barnes A; Boudjelal M; Sundrud M; Ghosh S; Yang J
J Immunol; 2014 Mar; 192(6):2564-75. PubMed ID: 24516202
[TBL] [Abstract][Full Text] [Related]
4. Identification of Tetraazacyclic Compounds as Novel Potent Inhibitors Antagonizing RORγt Activity and Suppressing Th17 Cell Differentiation.
Ding Q; Zhao M; Yu B; Bai C; Huang Z
PLoS One; 2015; 10(9):e0137711. PubMed ID: 26368822
[TBL] [Abstract][Full Text] [Related]
5. Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity.
Huh JR; Leung MW; Huang P; Ryan DA; Krout MR; Malapaka RR; Chow J; Manel N; Ciofani M; Kim SV; Cuesta A; Santori FR; Lafaille JJ; Xu HE; Gin DY; Rastinejad F; Littman DR
Nature; 2011 Apr; 472(7344):486-90. PubMed ID: 21441909
[TBL] [Abstract][Full Text] [Related]
6. In vivo regulation of gene expression and T helper type 17 differentiation by RORγt inverse agonists.
Skepner J; Trocha M; Ramesh R; Qu XA; Schmidt D; Baloglu E; Lobera M; Davis S; Nolan MA; Carlson TJ; Hill J; Ghosh S; Sundrud MS; Yang J
Immunology; 2015 Jul; 145(3):347-56. PubMed ID: 25604624
[TBL] [Abstract][Full Text] [Related]
7. Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms.
Xiao S; Yosef N; Yang J; Wang Y; Zhou L; Zhu C; Wu C; Baloglu E; Schmidt D; Ramesh R; Lobera M; Sundrud MS; Tsai PY; Xiang Z; Wang J; Xu Y; Lin X; Kretschmer K; Rahl PB; Young RA; Zhong Z; Hafler DA; Regev A; Ghosh S; Marson A; Kuchroo VK
Immunity; 2014 Apr; 40(4):477-89. PubMed ID: 24745332
[TBL] [Abstract][Full Text] [Related]
8. Antagonizing Retinoic Acid-Related-Orphan Receptor Gamma Activity Blocks the T Helper 17/Interleukin-17 Pathway Leading to Attenuated Pro-inflammatory Human Keratinocyte and Skin Responses.
Ecoeur F; Weiss J; Kaupmann K; Hintermann S; Orain D; Guntermann C
Front Immunol; 2019; 10():577. PubMed ID: 30972071
[TBL] [Abstract][Full Text] [Related]
9. AT-rich-interactive domain-containing protein 5A functions as a negative regulator of retinoic acid receptor-related orphan nuclear receptor γt-induced Th17 cell differentiation.
Saito Y; Kagami S; Sanayama Y; Ikeda K; Suto A; Kashiwakuma D; Furuta S; Iwamoto I; Nonaka K; Ohara O; Nakajima H
Arthritis Rheumatol; 2014 May; 66(5):1185-94. PubMed ID: 24782182
[TBL] [Abstract][Full Text] [Related]
10. Inhibition of RORγt activity and Th17 differentiation by a set of novel compounds.
Ding Q; Zhao M; Bai C; Yu B; Huang Z
BMC Immunol; 2015 May; 16():32. PubMed ID: 26021566
[TBL] [Abstract][Full Text] [Related]
11. Transcription Factor Retinoid-Related Orphan Receptor γt: A Promising Target for the Treatment of Psoriasis.
Tang L; Yang X; Liang Y; Xie H; Dai Z; Zheng G
Front Immunol; 2018; 9():1210. PubMed ID: 29899748
[TBL] [Abstract][Full Text] [Related]
12. Structural basis of digoxin that antagonizes RORgamma t receptor activity and suppresses Th17 cell differentiation and interleukin (IL)-17 production.
Fujita-Sato S; Ito S; Isobe T; Ohyama T; Wakabayashi K; Morishita K; Ando O; Isono F
J Biol Chem; 2011 Sep; 286(36):31409-17. PubMed ID: 21733845
[TBL] [Abstract][Full Text] [Related]
13. The emerging landscape of RORγt biology.
Lee JS; Cua DJ
Immunity; 2014 Apr; 40(4):451-2. PubMed ID: 24745326
[TBL] [Abstract][Full Text] [Related]
14. Transcriptional Regulators of T Helper 17 Cell Differentiation in Health and Autoimmune Diseases.
Capone A; Volpe E
Front Immunol; 2020; 11():348. PubMed ID: 32226427
[TBL] [Abstract][Full Text] [Related]
15. Pharmacological inhibition of RORγt suppresses the Th17 pathway and alleviates arthritis in vivo.
Guendisch U; Weiss J; Ecoeur F; Riker JC; Kaupmann K; Kallen J; Hintermann S; Orain D; Dawson J; Billich A; Guntermann C
PLoS One; 2017; 12(11):e0188391. PubMed ID: 29155882
[TBL] [Abstract][Full Text] [Related]
16. Pharmacologic modulation of RORγt translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis.
Xue X; Soroosh P; De Leon-Tabaldo A; Luna-Roman R; Sablad M; Rozenkrants N; Yu J; Castro G; Banie H; Fung-Leung WP; Santamaria-Babi L; Schlueter T; Albers M; Leonard K; Budelsky AL; Fourie AM
Sci Rep; 2016 Dec; 6():37977. PubMed ID: 27905482
[TBL] [Abstract][Full Text] [Related]
17. Silencing RORγt in Human CD4
Shi X; Song P; Tao S; Zhang X; Chu CQ
Sci Rep; 2019 Jul; 9(1):10375. PubMed ID: 31316164
[TBL] [Abstract][Full Text] [Related]
18. RORγt-specific transcriptional interactomic inhibition suppresses autoimmunity associated with TH17 cells.
Park TY; Park SD; Cho JY; Moon JS; Kim NY; Park K; Seong RH; Lee SW; Morio T; Bothwell AL; Lee SK
Proc Natl Acad Sci U S A; 2014 Dec; 111(52):18673-8. PubMed ID: 25527718
[TBL] [Abstract][Full Text] [Related]
19. Novel benzenediamine derivative FC99 ameliorates zymosan-induced arthritis by inhibiting RORγt expression and Th17 cell differentiation.
Ji J; Dou H; Li X; Song Y; Li X; Li E; Tan R; Hou Y
Acta Biochim Biophys Sin (Shanghai); 2014 Oct; 46(10):829-36. PubMed ID: 25187413
[TBL] [Abstract][Full Text] [Related]
20. Inhibiting RORγt/Th17 axis for autoimmune disorders.
Isono F; Fujita-Sato S; Ito S
Drug Discov Today; 2014 Aug; 19(8):1205-11. PubMed ID: 24792721
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]