These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
22. Design, synthesis and biological evaluation of novel 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole triazole derivatives as potent TRPV1 antagonists. Li J; Nie C; Qiao Y; Hu J; Li Q; Wang Q; Pu X; Yan L; Qian H Eur J Med Chem; 2019 Sep; 178():433-445. PubMed ID: 31202991 [TBL] [Abstract][Full Text] [Related]
24. 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent transient receptor potential vanilloid 1 (TRPV1) antagonists: structure-activity relationships of 2-amino derivatives in the N-(6-trifluoromethylpyridin-3-ylmethyl) C-region. Kim MS; Ryu H; Kang DW; Cho SH; Seo S; Park YS; Kim MY; Kwak EJ; Kim YS; Bhondwe RS; Kim HS; Park SG; Son K; Choi S; DeAndrea-Lazarus IA; Pearce LV; Blumberg PM; Frank R; Bahrenberg G; Stockhausen H; Kögel BY; Schiene K; Christoph T; Lee J J Med Chem; 2012 Oct; 55(19):8392-408. PubMed ID: 22957803 [TBL] [Abstract][Full Text] [Related]
27. Targeting TRPV1 for pain relief: limits, losers and laurels. Szallasi A; Sheta M Expert Opin Investig Drugs; 2012 Sep; 21(9):1351-69. PubMed ID: 22780443 [TBL] [Abstract][Full Text] [Related]
28. Novel thiazolo[3,2-b]-1,2,4-triazoles derived from naproxen with analgesic/anti-inflammatory properties: Synthesis, biological evaluation and molecular modeling studies. Sarigol D; Uzgoren-Baran A; Tel BC; Somuncuoglu EI; Kazkayasi I; Ozadali-Sari K; Unsal-Tan O; Okay G; Ertan M; Tozkoparan B Bioorg Med Chem; 2015 May; 23(10):2518-28. PubMed ID: 25868745 [TBL] [Abstract][Full Text] [Related]
29. Discovery of indane propanamides as potent and selective TRPV1 antagonists. Ahn S; Kim YS; Kim MS; Ann J; Ha H; Yoo YD; Kim YH; Blumberg PM; Frank-Foltyn R; Bahrenberg G; Stockhausen H; Christoph T; Lee J Bioorg Med Chem Lett; 2020 Feb; 30(3):126838. PubMed ID: 31864799 [TBL] [Abstract][Full Text] [Related]
30. N-palmitoyl-vanillamide (palvanil) is a non-pungent analogue of capsaicin with stronger desensitizing capability against the TRPV1 receptor and anti-hyperalgesic activity. De Petrocellis L; Guida F; Moriello AS; De Chiaro M; Piscitelli F; de Novellis V; Maione S; Di Marzo V Pharmacol Res; 2011 Apr; 63(4):294-9. PubMed ID: 21215315 [TBL] [Abstract][Full Text] [Related]
31. Phenylquinoline transient receptor potential vanilloid 1 antagonists for the treatment of pain: Discovery of 1-(2-phenylquinoline-4-carbonyl)-N-(4-(trifluoromethyl)phenyl)pyrrolidine-3-carboxamide. Liao C; Liu Y; Liu C; Zhou J; Li H; Wang N; Li J; Liu T; Ghaleb H; Huang W; Qian H Bioorg Med Chem; 2018 Feb; 26(4):845-854. PubMed ID: 29317149 [TBL] [Abstract][Full Text] [Related]
32. The nociception induced by glutamate in mice is potentiated by protons released into the solution. Meotti FC; Coelho Idos S; Santos AR J Pain; 2010 Jun; 11(6):570-8. PubMed ID: 20338819 [TBL] [Abstract][Full Text] [Related]
33. Discovery of 1-(1H-indazol-4-yl)-3-((1-phenyl-1H-pyrazol-5-yl)methyl) ureas as potent and thermoneutral TRPV1 antagonists. Kang JM; Kwon SO; Ann J; Blumberg PM; Ha H; Yoo YD; Frank-Foltyn R; Lesch B; Bahrenberg G; Stockhausen H; Christoph T; Lee J Bioorg Med Chem Lett; 2020 Dec; 30(23):127548. PubMed ID: 32931910 [TBL] [Abstract][Full Text] [Related]
34. Antihyperalgesic effects of (R,E)-N-(2-hydroxy-2,3-dihydro-1H-inden-4-yl)-3-(2-(piperidin-1-yl)-4-(trifluoromethyl)phenyl)-acrylamide (AMG8562), a novel transient receptor potential vanilloid type 1 modulator that does not cause hyperthermia in rats. Lehto SG; Tamir R; Deng H; Klionsky L; Kuang R; Le A; Lee D; Louis JC; Magal E; Manning BH; Rubino J; Surapaneni S; Tamayo N; Wang T; Wang J; Wang J; Wang W; Youngblood B; Zhang M; Zhu D; Norman MH; Gavva NR J Pharmacol Exp Ther; 2008 Jul; 326(1):218-29. PubMed ID: 18420600 [TBL] [Abstract][Full Text] [Related]
35. Pyridine C-region analogs of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists. Ryu H; Seo S; Lee JY; Ha TH; Lee S; Jung A; Ann J; Kim SE; Yoon S; Hong M; Blumberg PM; Frank-Foltyn R; Bahrenberg G; Schiene K; Stockhausen H; Christoph T; Frormann S; Lee J Eur J Med Chem; 2015 Mar; 93():101-8. PubMed ID: 25659771 [TBL] [Abstract][Full Text] [Related]
36. Design and synthesis of 2-phenoxynicotinic acid hydrazides as anti-inflammatory and analgesic agents. Moradi A; Navidpour L; Amini M; Sadeghian H; Shadnia H; Firouzi O; Miri R; Ebrahimi SE; Abdollahi M; Zahmatkesh MH; Shafiee A Arch Pharm (Weinheim); 2010 Sep; 343(9):509-18. PubMed ID: 20806271 [TBL] [Abstract][Full Text] [Related]
37. Synthesis and pharmacological evaluation of carbamic acid 1-phenyl-3-(4-phenyl-piperazine-1-yl)-propyl ester derivatives as new analgesic agents. Chae E; Yi H; Choi Y; Cho H; Lee K; Moon H Bioorg Med Chem Lett; 2012 Apr; 22(7):2434-9. PubMed ID: 22386241 [TBL] [Abstract][Full Text] [Related]
38. 4-Aminophenyl acetamides and propanamides as potent transient receptor potential vanilloid 1 (TRPV1) ligands. Kim C; Ann J; Lee S; Kim E; Choi S; Blumberg PM; Frank-Foltyn R; Bahrenberg G; Stockhausen H; Christoph T; Lee J Bioorg Med Chem; 2018 Aug; 26(15):4509-4517. PubMed ID: 30078610 [TBL] [Abstract][Full Text] [Related]
39. New orally effective 3-(2-nitro)phenylpropanamide analgesic derivatives: synthesis and antinociceptive evaluation. Since M; Freret T; Nee G; Terme T; Vanelle P; Boulouard M Eur J Med Chem; 2013 Nov; 69():728-34. PubMed ID: 24095764 [TBL] [Abstract][Full Text] [Related]
40. Transient receptor potential vanilloid 1 as a therapeutic target in analgesia. Szolcsányi J; Pintér E Expert Opin Ther Targets; 2013 Jun; 17(6):641-57. PubMed ID: 23421411 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]