250 related articles for article (PubMed ID: 26797121)
1. Protein Kinase A (PKA) Type I Interacts with P-Rex1, a Rac Guanine Nucleotide Exchange Factor: EFFECT ON PKA LOCALIZATION AND P-Rex1 SIGNALING.
Chávez-Vargas L; Adame-García SR; Cervantes-Villagrana RD; Castillo-Kauil A; Bruystens JG; Fukuhara S; Taylor SS; Mochizuki N; Reyes-Cruz G; Vázquez-Prado J
J Biol Chem; 2016 Mar; 291(12):6182-99. PubMed ID: 26797121
[TBL] [Abstract][Full Text] [Related]
2. cAMP-dependent activation of the Rac guanine exchange factor P-REX1 by type I protein kinase A (PKA) regulatory subunits.
Adame-García SR; Cervantes-Villagrana RD; Orduña-Castillo LB; Del Rio JC; Gutkind JS; Reyes-Cruz G; Taylor SS; Vázquez-Prado J
J Biol Chem; 2019 Feb; 294(7):2232-2246. PubMed ID: 30530493
[TBL] [Abstract][Full Text] [Related]
3. The first DEP domain of the RhoGEF P-Rex1 autoinhibits activity and contributes to membrane binding.
Ravala SK; Hopkins JB; Plescia CB; Allgood SR; Kane MA; Cash JN; Stahelin RV; Tesmer JJG
J Biol Chem; 2020 Sep; 295(36):12635-12647. PubMed ID: 32661198
[TBL] [Abstract][Full Text] [Related]
4. Gβγ signaling to the chemotactic effector P-REX1 and mammalian cell migration is directly regulated by Gα
Cervantes-Villagrana RD; Adame-García SR; García-Jiménez I; Color-Aparicio VM; Beltrán-Navarro YM; König GM; Kostenis E; Reyes-Cruz G; Gutkind JS; Vázquez-Prado J
J Biol Chem; 2019 Jan; 294(2):531-546. PubMed ID: 30446620
[TBL] [Abstract][Full Text] [Related]
5. Domain-domain interaction of P-Rex1 is essential for the activation and inhibition by G protein betagamma subunits and PKA.
Urano D; Nakata A; Mizuno N; Tago K; Itoh H
Cell Signal; 2008 Aug; 20(8):1545-54. PubMed ID: 18514484
[TBL] [Abstract][Full Text] [Related]
6. Phosphatidylinositol 3,4,5-triphosphate-dependent Rac exchanger 1 (P-Rex-1), a guanine nucleotide exchange factor for Rac, mediates angiogenic responses to stromal cell-derived factor-1/chemokine stromal cell derived factor-1 (SDF-1/CXCL-12) linked to Rac activation, endothelial cell migration, and in vitro angiogenesis.
Carretero-Ortega J; Walsh CT; Hernández-García R; Reyes-Cruz G; Brown JH; Vázquez-Prado J
Mol Pharmacol; 2010 Mar; 77(3):435-42. PubMed ID: 20018810
[TBL] [Abstract][Full Text] [Related]
7. Gβγ recruits and activates P-Rex1 via two independent binding interfaces.
Cervantes-Villagrana RD; Beltrán-Navarro YM; García-Jiménez I; Adame-García SR; Olguín-Olguín A; Reyes-Cruz G; Vázquez-Prado J
Biochem Biophys Res Commun; 2021 Feb; 539():20-27. PubMed ID: 33412417
[TBL] [Abstract][Full Text] [Related]
8. Norbin Stimulates the Catalytic Activity and Plasma Membrane Localization of the Guanine-Nucleotide Exchange Factor P-Rex1.
Pan D; Barber MA; Hornigold K; Baker MJ; Toth JM; Oxley D; Welch HC
J Biol Chem; 2016 Mar; 291(12):6359-75. PubMed ID: 26792863
[TBL] [Abstract][Full Text] [Related]
9. The Rho guanine nucleotide exchange factor P-Rex1 as a potential drug target for cancer metastasis and inflammatory diseases.
Ye RD
Pharmacol Res; 2020 Mar; 153():104676. PubMed ID: 32006571
[TBL] [Abstract][Full Text] [Related]
10. Phosphorylation of P-Rex1 by the cyclic AMP-dependent protein kinase inhibits the phosphatidylinositiol (3,4,5)-trisphosphate and Gbetagamma-mediated regulation of its activity.
Mayeenuddin LH; Garrison JC
J Biol Chem; 2006 Jan; 281(4):1921-8. PubMed ID: 16301320
[TBL] [Abstract][Full Text] [Related]
11. Regulation of P-Rex1 by phosphatidylinositol (3,4,5)-trisphosphate and Gbetagamma subunits.
Hill K; Krugmann S; Andrews SR; Coadwell WJ; Finan P; Welch HC; Hawkins PT; Stephens LR
J Biol Chem; 2005 Feb; 280(6):4166-73. PubMed ID: 15545267
[TBL] [Abstract][Full Text] [Related]
12. P-Rex1 links mammalian target of rapamycin signaling to Rac activation and cell migration.
Hernández-Negrete I; Carretero-Ortega J; Rosenfeldt H; Hernández-García R; Calderón-Salinas JV; Reyes-Cruz G; Gutkind JS; Vázquez-Prado J
J Biol Chem; 2007 Aug; 282(32):23708-15. PubMed ID: 17565979
[TBL] [Abstract][Full Text] [Related]
13. Sphingosine-1-phosphate receptor S1P1 is regulated by direct interactions with P-Rex1, a Rac guanine nucleotide exchange factor.
Ledezma-Sánchez BA; García-Regalado A; Guzmán-Hernández ML; Vázquez-Prado J
Biochem Biophys Res Commun; 2010 Jan; 391(4):1647-52. PubMed ID: 20036214
[TBL] [Abstract][Full Text] [Related]
14. The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1·Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1·Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells.
Lucato CM; Halls ML; Ooms LM; Liu HJ; Mitchell CA; Whisstock JC; Ellisdon AM
J Biol Chem; 2015 Aug; 290(34):20827-20840. PubMed ID: 26112412
[TBL] [Abstract][Full Text] [Related]
15. The guanine-nucleotide-exchange factor P-Rex1 is activated by protein phosphatase 1α.
Barber MA; Hendrickx A; Beullens M; Ceulemans H; Oxley D; Thelen S; Thelen M; Bollen M; Welch HC
Biochem J; 2012 Apr; 443(1):173-83. PubMed ID: 22242915
[TBL] [Abstract][Full Text] [Related]
16. Signaling requirements for translocation of P-Rex1, a key Rac2 exchange factor involved in chemoattractant-stimulated human neutrophil function.
Zhao T; Nalbant P; Hoshino M; Dong X; Wu D; Bokoch GM
J Leukoc Biol; 2007 Apr; 81(4):1127-36. PubMed ID: 17227822
[TBL] [Abstract][Full Text] [Related]
17. P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils.
Damoulakis G; Gambardella L; Rossman KL; Lawson CD; Anderson KE; Fukui Y; Welch HC; Der CJ; Stephens LR; Hawkins PT
J Cell Sci; 2014 Jun; 127(Pt 11):2589-600. PubMed ID: 24659802
[TBL] [Abstract][Full Text] [Related]
18. Cryo-electron microscopy structure and analysis of the P-Rex1-Gβγ signaling scaffold.
Cash JN; Urata S; Li S; Ravala SK; Avramova LV; Shost MD; Gutkind JS; Tesmer JJG; Cianfrocco MA
Sci Adv; 2019 Oct; 5(10):eaax8855. PubMed ID: 31663027
[TBL] [Abstract][Full Text] [Related]
19. Mapping the Free Energy Landscape of PKA Inhibition and Activation: A Double-Conformational Selection Model for the Tandem cAMP-Binding Domains of PKA RIα.
Akimoto M; McNicholl ET; Ramkissoon A; Moleschi K; Taylor SS; Melacini G
PLoS Biol; 2015; 13(11):e1002305. PubMed ID: 26618408
[TBL] [Abstract][Full Text] [Related]
20. Involvement of a Rac activator,P-Rex1, in neurotrophin-derived signaling and neuronal migration.
Yoshizawa M; Kawauchi T; Sone M; Nishimura YV; Terao M; Chihama K; Nabeshima Y; Hoshino M
J Neurosci; 2005 Apr; 25(17):4406-19. PubMed ID: 15858067
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
