BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 26808161)

  • 1. The role of glucuronidation in drug resistance.
    Mazerska Z; Mróz A; Pawłowska M; Augustin E
    Pharmacol Ther; 2016 Mar; 159():35-55. PubMed ID: 26808161
    [TBL] [Abstract][Full Text] [Related]  

  • 2. [Glucuronidation of antitumour therapeutics--detoxification, mechanism of resistance or prodrug formation?].
    Mróz A; Mazerska Z
    Postepy Hig Med Dosw (Online); 2015 Dec; 69():1462-77. PubMed ID: 27259218
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transcriptional regulation of human UDP-glucuronosyltransferase genes.
    Hu DG; Meech R; McKinnon RA; Mackenzie PI
    Drug Metab Rev; 2014 Nov; 46(4):421-58. PubMed ID: 25336387
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glucuronidation as a mechanism of intrinsic drug resistance in human colon cancer: reversal of resistance by food additives.
    Cummings J; Ethell BT; Jardine L; Boyd G; Macpherson JS; Burchell B; Smyth JF; Jodrell DI
    Cancer Res; 2003 Dec; 63(23):8443-50. PubMed ID: 14679008
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Warfarin is an effective modifier of multiple UDP-glucuronosyltransferase enzymes: evaluation of its potential to alter the pharmacokinetics of zidovudine.
    Sun H; Zhang T; Wu Z; Wu B
    J Pharm Sci; 2015 Jan; 104(1):244-56. PubMed ID: 25393417
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Coupling of UDP-glucuronosyltransferases and multidrug resistance-associated proteins is responsible for the intestinal disposition and poor bioavailability of emodin.
    Liu W; Feng Q; Li Y; Ye L; Hu M; Liu Z
    Toxicol Appl Pharmacol; 2012 Dec; 265(3):316-24. PubMed ID: 22982073
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Roles of human UDP-glucuronosyltransferases in clearance and homeostasis of endogenous substrates, and functional implications.
    Bock KW
    Biochem Pharmacol; 2015 Jul; 96(2):77-82. PubMed ID: 25937523
    [TBL] [Abstract][Full Text] [Related]  

  • 8. From differential induction of UDP-glucuronosyltransferases in rat liver to characterization of responsible ligand-activated transcription factors, and their multilevel crosstalk in humans.
    Bock KW
    Biochem Pharmacol; 2011 Jul; 82(1):9-16. PubMed ID: 21420387
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phytochemical regulation of UDP-glucuronosyltransferases: implications for cancer prevention.
    Saracino MR; Lampe JW
    Nutr Cancer; 2007; 59(2):121-41. PubMed ID: 18001207
    [TBL] [Abstract][Full Text] [Related]  

  • 10. UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Kiang TK; Ensom MH; Chang TK
    Pharmacol Ther; 2005 Apr; 106(1):97-132. PubMed ID: 15781124
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Roles of UDP-glucuronosyltransferases in chemical carcinogenesis.
    Bock KW
    Crit Rev Biochem Mol Biol; 1991; 26(2):129-50. PubMed ID: 1914494
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human UDP-glucuronosyltransferase expression in insect cells: ratio of active to inactive recombinant proteins and the effects of a C-terminal his-tag on glucuronidation kinetics.
    Zhang H; Patana AS; Mackenzie PI; Ikushiro S; Goldman A; Finel M
    Drug Metab Dispos; 2012 Oct; 40(10):1935-44. PubMed ID: 22782802
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Investigation into UDP-glucuronosyltransferase (UGT) enzyme kinetics of imidazole- and triazole-containing antifungal drugs in human liver microsomes and recombinant UGT enzymes.
    Bourcier K; Hyland R; Kempshall S; Jones R; Maximilien J; Irvine N; Jones B
    Drug Metab Dispos; 2010 Jun; 38(6):923-9. PubMed ID: 20304965
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Induction of rat UDP-glucuronosyltransferases in liver and duodenum by microsomal enzyme inducers that activate various transcriptional pathways.
    Shelby MK; Klaassen CD
    Drug Metab Dispos; 2006 Oct; 34(10):1772-8. PubMed ID: 16855052
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Drug-drug interactions for UDP-glucuronosyltransferase substrates: a pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios.
    Williams JA; Hyland R; Jones BC; Smith DA; Hurst S; Goosen TC; Peterkin V; Koup JR; Ball SE
    Drug Metab Dispos; 2004 Nov; 32(11):1201-8. PubMed ID: 15304429
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Multiplexed Targeted Quantitative Proteomics Predicts Hepatic Glucuronidation Potential.
    Margaillan G; Rouleau M; Klein K; Fallon JK; Caron P; Villeneuve L; Smith PC; Zanger UM; Guillemette C
    Drug Metab Dispos; 2015 Sep; 43(9):1331-5. PubMed ID: 26076694
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Kinetics of acetaminophen glucuronidation by UDP-glucuronosyltransferases 1A1, 1A6, 1A9 and 2B15. Potential implications in acetaminophen-induced hepatotoxicity.
    Mutlib AE; Goosen TC; Bauman JN; Williams JA; Kulkarni S; Kostrubsky S
    Chem Res Toxicol; 2006 May; 19(5):701-9. PubMed ID: 16696573
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular Pathways: GLI1-Induced Drug Glucuronidation in Resistant Cancer Cells.
    Zahreddine HA; Borden KL
    Clin Cancer Res; 2015 May; 21(10):2207-10. PubMed ID: 25810373
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Drug glucuronidation and disposition in brain].
    Zhang ZQ; Sheng L; Li Y
    Yao Xue Xue Bao; 2016 Nov; 51(11):1674-80. PubMed ID: 29908109
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glucuronidation of fimasartan, a new angiotensin receptor antagonist, is mainly mediated by UGT1A3.
    Jeong ES; Kim YW; Kim HJ; Shin HJ; Shin JG; Kim KH; Chi YH; Paik SH; Kim DH
    Xenobiotica; 2015 Jan; 45(1):10-8. PubMed ID: 25034008
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.