These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

123 related articles for article (PubMed ID: 26808470)

  • 1. Synthesis, Activity, and Docking Study of Novel Phenylthiazole-Carboxamido Acid Derivatives as FFA2 Agonists.
    Ma L; Wang T; Shi M; Fu P; Pei H; Ye H
    Chem Biol Drug Des; 2016 Jul; 88(1):26-37. PubMed ID: 26808470
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3.
    Schmidt J; Smith NJ; Christiansen E; Tikhonova IG; Grundmann M; Hudson BD; Ward RJ; Drewke C; Milligan G; Kostenis E; Ulven T
    J Biol Chem; 2011 Mar; 286(12):10628-40. PubMed ID: 21220428
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification and functional characterization of allosteric agonists for the G protein-coupled receptor FFA2.
    Lee T; Schwandner R; Swaminath G; Weiszmann J; Cardozo M; Greenberg J; Jaeckel P; Ge H; Wang Y; Jiao X; Liu J; Kayser F; Tian H; Li Y
    Mol Pharmacol; 2008 Dec; 74(6):1599-609. PubMed ID: 18818303
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Free fatty acid receptors: structural models and elucidation of ligand binding interactions.
    Tikhonova IG; Poerio E
    BMC Struct Biol; 2015 Sep; 15():16. PubMed ID: 26346819
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptor.
    Hudson BD; Due-Hansen ME; Christiansen E; Hansen AM; Mackenzie AE; Murdoch H; Pandey SK; Ward RJ; Marquez R; Tikhonova IG; Ulven T; Milligan G
    J Biol Chem; 2013 Jun; 288(24):17296-312. PubMed ID: 23589301
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Agonism and allosterism: the pharmacology of the free fatty acid receptors FFA2 and FFA3.
    Milligan G; Stoddart LA; Smith NJ
    Br J Pharmacol; 2009 Sep; 158(1):146-53. PubMed ID: 19719777
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutational analysis of G-protein coupled receptor--FFA2.
    Swaminath G; Jaeckel P; Guo Q; Cardozo M; Weiszmann J; Lindberg R; Wang Y; Schwandner R; Li Y
    Biochem Biophys Res Commun; 2011 Feb; 405(1):122-7. PubMed ID: 21216233
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterisation of small molecule ligands 4CMTB and 2CTAP as modulators of human FFA2 receptor signalling.
    Schofield ZV; Croker D; Robertson AAB; Massey NL; Donovan C; Tee E; Edwards D; Woodruff TM; Halai R; Hansbro PM; Cooper MA
    Sci Rep; 2018 Dec; 8(1):17819. PubMed ID: 30546040
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Non-equivalence of Key Positively Charged Residues of the Free Fatty Acid 2 Receptor in the Recognition and Function of Agonist Versus Antagonist Ligands.
    Sergeev E; Hansen AH; Pandey SK; MacKenzie AE; Hudson BD; Ulven T; Milligan G
    J Biol Chem; 2016 Jan; 291(1):303-17. PubMed ID: 26518871
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator.
    Smith NJ; Ward RJ; Stoddart LA; Hudson BD; Kostenis E; Ulven T; Morris JC; Tränkle C; Tikhonova IG; Adams DR; Milligan G
    Mol Pharmacol; 2011 Jul; 80(1):163-73. PubMed ID: 21498659
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Extracellular ionic locks determine variation in constitutive activity and ligand potency between species orthologs of the free fatty acid receptors FFA2 and FFA3.
    Hudson BD; Tikhonova IG; Pandey SK; Ulven T; Milligan G
    J Biol Chem; 2012 Nov; 287(49):41195-209. PubMed ID: 23066016
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Application of GPCR Structures for Modelling of Free Fatty Acid Receptors.
    Tikhonova IG
    Handb Exp Pharmacol; 2017; 236():57-77. PubMed ID: 27757764
    [TBL] [Abstract][Full Text] [Related]  

  • 13. High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875.
    Srivastava A; Yano J; Hirozane Y; Kefala G; Gruswitz F; Snell G; Lane W; Ivetac A; Aertgeerts K; Nguyen J; Jennings A; Okada K
    Nature; 2014 Sep; 513(7516):124-7. PubMed ID: 25043059
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ligands at the Free Fatty Acid Receptors 2/3 (GPR43/GPR41).
    Milligan G; Bolognini D; Sergeev E
    Handb Exp Pharmacol; 2017; 236():17-32. PubMed ID: 27757758
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets.
    Ulven T
    Front Endocrinol (Lausanne); 2012; 3():111. PubMed ID: 23060857
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Selective FFA2 Agonism Appears to Act via Intestinal PYY to Reduce Transit and Food Intake but Does Not Improve Glucose Tolerance in Mouse Models.
    Forbes S; Stafford S; Coope G; Heffron H; Real K; Newman R; Davenport R; Barnes M; Grosse J; Cox H
    Diabetes; 2015 Nov; 64(11):3763-71. PubMed ID: 26239054
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Conserved polar residues in transmembrane domains V, VI, and VII of free fatty acid receptor 2 and free fatty acid receptor 3 are required for the binding and function of short chain fatty acids.
    Stoddart LA; Smith NJ; Jenkins L; Brown AJ; Milligan G
    J Biol Chem; 2008 Nov; 283(47):32913-24. PubMed ID: 18801738
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Chemogenetics defines a short-chain fatty acid receptor gut-brain axis.
    Barki N; Bolognini D; Börjesson U; Jenkins L; Riddell J; Hughes DI; Ulven T; Hudson BD; Ulven ER; Dekker N; Tobin AB; Milligan G
    Elife; 2022 Mar; 11():. PubMed ID: 35229717
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The first synthetic agonists of FFA2: Discovery and SAR of phenylacetamides as allosteric modulators.
    Wang Y; Jiao X; Kayser F; Liu J; Wang Z; Wanska M; Greenberg J; Weiszmann J; Ge H; Tian H; Wong S; Schwandner R; Lee T; Li Y
    Bioorg Med Chem Lett; 2010 Jan; 20(2):493-8. PubMed ID: 20005104
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification and characterization of the free fatty acid receptor 2 (FFA2) and a novel functional FFA2-like receptor (FFA2L) for short-chain fatty acids in pigs: evidence for the existence of a duplicated FFA2 gene (FFA2L) in some mammalian species.
    Zhang J; Cheng S; Wang Y; Yu X; Li J
    Domest Anim Endocrinol; 2014 Apr; 47():108-18.e1. PubMed ID: 24315753
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.