BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

222 related articles for article (PubMed ID: 26809098)

  • 1. A soluble form of the interleukin-6 family signal transducer gp130 is dimerized via a C-terminal disulfide bridge resulting from alternative mRNA splicing.
    Wolf J; Waetzig GH; Reinheimer TM; Scheller J; Rose-John S; Garbers C
    Biochem Biophys Res Commun; 2016 Feb; 470(4):870-6. PubMed ID: 26809098
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Different Soluble Forms of the Interleukin-6 Family Signal Transducer gp130 Fine-tune the Blockade of Interleukin-6 Trans-signaling.
    Wolf J; Waetzig GH; Chalaris A; Reinheimer TM; Wege H; Rose-John S; Garbers C
    J Biol Chem; 2016 Jul; 291(31):16186-96. PubMed ID: 27226573
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Alternative intronic polyadenylation generates the interleukin-6 trans-signaling inhibitor sgp130-E10.
    Sommer J; Garbers C; Wolf J; Trad A; Moll JM; Sack M; Fischer R; Grötzinger J; Waetzig GH; Floss DM; Scheller J
    J Biol Chem; 2014 Aug; 289(32):22140-50. PubMed ID: 24973212
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-guided optimization of the interleukin-6 trans-signaling antagonist sgp130.
    Tenhumberg S; Waetzig GH; Chalaris A; Rabe B; Seegert D; Scheller J; Rose-John S; Grötzinger J
    J Biol Chem; 2008 Oct; 283(40):27200-7. PubMed ID: 18650419
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The balance of interleukin (IL)-6, IL-6·soluble IL-6 receptor (sIL-6R), and IL-6·sIL-6R·sgp130 complexes allows simultaneous classic and trans-signaling.
    Baran P; Hansen S; Waetzig GH; Akbarzadeh M; Lamertz L; Huber HJ; Ahmadian MR; Moll JM; Scheller J
    J Biol Chem; 2018 May; 293(18):6762-6775. PubMed ID: 29559558
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Soluble gp130 is up-regulated in the implantation window and shows altered secretion in patients with primary unexplained infertility.
    Sherwin JR; Smith SK; Wilson A; Sharkey AM
    J Clin Endocrinol Metab; 2002 Aug; 87(8):3953-60. PubMed ID: 12161539
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Soluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responses.
    Jostock T; Müllberg J; Ozbek S; Atreya R; Blinn G; Voltz N; Fischer M; Neurath MF; Rose-John S
    Eur J Biochem; 2001 Jan; 268(1):160-7. PubMed ID: 11121117
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interleukin-6 and its receptors: a highly regulated and dynamic system.
    Wolf J; Rose-John S; Garbers C
    Cytokine; 2014 Nov; 70(1):11-20. PubMed ID: 24986424
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Influence of humanized anti-IL-6R antibody, tocilizumab on the activity of soluble gp130, natural inhibitor of IL-6 signaling.
    Hashizume M; Mihara M
    Rheumatol Int; 2009 Feb; 29(4):397-401. PubMed ID: 18802703
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The N-terminus of gp130 is critical for the formation of the high-affinity interleukin-6 receptor complex.
    Moritz RL; Ward LD; Tu GF; Fabri LJ; Ji H; Yasukawa K; Simpson RJ
    Growth Factors; 1999; 16(4):265-78. PubMed ID: 10427501
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Functional expression of a biologically active fragment of soluble gp130 as an ELP-fusion protein in transgenic plants: purification via inverse transition cycling.
    Lin M; Rose-John S; Grötzinger J; Conrad U; Scheller J
    Biochem J; 2006 Sep; 398(3):577-83. PubMed ID: 16716147
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Soluble IL-6 receptor potentiates the antagonistic activity of soluble gp130 on IL-6 responses.
    Müller-Newen G; Küster A; Hemmann U; Keul R; Horsten U; Martens A; Graeve L; Wijdenes J; Heinrich PC
    J Immunol; 1998 Dec; 161(11):6347-55. PubMed ID: 9834125
    [TBL] [Abstract][Full Text] [Related]  

  • 13. IL-6 trans-signaling system in intra-amniotic inflammation, preterm birth, and preterm premature rupture of the membranes.
    Lee SY; Buhimschi IA; Dulay AT; Ali UA; Zhao G; Abdel-Razeq SS; Bahtiyar MO; Thung SF; Funai EF; Buhimschi CS
    J Immunol; 2011 Mar; 186(5):3226-36. PubMed ID: 21282511
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of classic signaling is a novel function of soluble glycoprotein 130 (sgp130), which is controlled by the ratio of interleukin 6 and soluble interleukin 6 receptor.
    Garbers C; Thaiss W; Jones GW; Waetzig GH; Lorenzen I; Guilhot F; Lissilaa R; Ferlin WG; Grötzinger J; Jones SA; Rose-John S; Scheller J
    J Biol Chem; 2011 Dec; 286(50):42959-70. PubMed ID: 21990364
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vivo modulation of soluble "antagonistic" IL-6 receptor synthesis and release in ESRD.
    Memoli B; Grandaliano G; Soccio M; Postiglione L; Guida B; Bisesti V; Esposito P; Procino A; Marrone D; Michael A; Andreucci M; Schena FP; Pertosa G
    J Am Soc Nephrol; 2005 Apr; 16(4):1099-107. PubMed ID: 15716332
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Soluble gp130 prevents interleukin-6 and interleukin-11 cluster signaling but not intracellular autocrine responses.
    Lamertz L; Rummel F; Polz R; Baran P; Hansen S; Waetzig GH; Moll JM; Floss DM; Scheller J
    Sci Signal; 2018 Oct; 11(550):. PubMed ID: 30279168
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Altered interleukin-6 receptor, IL-6R and gp130, production and expression and decreased SOCS-3 expression in placentas from women with pre-eclampsia.
    Zhao S; Gu Y; Dong Q; Fan R; Wang Y
    Placenta; 2008 Dec; 29(12):1024-8. PubMed ID: 18986700
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Circulating interleukin 6 and soluble forms of its receptors in relation to resting energy expenditure in women with anorexia nervosa.
    Karczewska-Kupczewska M; Adamska A; Nikołajuk A; Otziomek E; Górska M; Kowalska I; Strączkowski M
    Clin Endocrinol (Oxf); 2013 Dec; 79(6):812-6. PubMed ID: 23199226
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Glycoprotein 130 polymorphism predicts soluble glycoprotein 130 levels.
    Wonnerth A; Katsaros KM; Krychtiuk KA; Speidl WS; Kaun C; Thaler K; Huber K; Wojta J; Maurer G; Seljeflot I; Arnesen H; Weiss TW
    Metabolism; 2014 May; 63(5):647-53. PubMed ID: 24629561
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interleukin-6 trans-signaling and colonic cancer associated with inflammatory bowel disease.
    Chalaris A; Schmidt-Arras D; Yamamoto K; Rose-John S
    Dig Dis; 2012; 30(5):492-9. PubMed ID: 23108305
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.