312 related articles for article (PubMed ID: 26813254)
1. PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus.
Mellado-Gil JM; Jiménez-Moreno CM; Martin-Montalvo A; Alvarez-Mercado AI; Fuente-Martin E; Cobo-Vuilleumier N; Lorenzo PI; Bru-Tari E; Herrera-Gómez Ide G; López-Noriega L; Pérez-Florido J; Santoyo-López J; Spyrantis A; Meda P; Boehm BO; Quesada I; Gauthier BR
Diabetologia; 2016 Apr; 59(4):755-65. PubMed ID: 26813254
[TBL] [Abstract][Full Text] [Related]
2. In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice.
Hu He KH; Lorenzo PI; Brun T; Jimenez Moreno CM; Aeberhard D; Vallejo Ortega J; Cornu M; Thorel F; Gjinovci A; Thorens B; Herrera PL; Meda P; Wollheim CB; Gauthier BR
Diabetes; 2011 Jun; 60(6):1705-15. PubMed ID: 21521872
[TBL] [Abstract][Full Text] [Related]
3. PAX4 Defines an Expandable β-Cell Subpopulation in the Adult Pancreatic Islet.
Lorenzo PI; Fuente-Martín E; Brun T; Cobo-Vuilleumier N; Jimenez-Moreno CM; G Herrera Gomez I; López Noriega L; Mellado-Gil JM; Martin-Montalvo A; Soria B; Gauthier BR
Sci Rep; 2015 Oct; 5():15672. PubMed ID: 26503027
[TBL] [Abstract][Full Text] [Related]
4. The diabetes-linked transcription factor Pax4 is expressed in human pancreatic islets and is activated by mitogens and GLP-1.
Brun T; Hu He KH; Lupi R; Boehm B; Wojtusciszyn A; Sauter N; Donath M; Marchetti P; Maedler K; Gauthier BR
Hum Mol Genet; 2008 Feb; 17(4):478-89. PubMed ID: 17989064
[TBL] [Abstract][Full Text] [Related]
5. Pax4 Gene Delivery Improves Islet Transplantation Efficacy by Promoting β Cell Survival and α-to-β Cell Transdifferentiation.
Parajuli KR; Zhang Y; Cao AM; Wang H; Fonseca VA; Wu H
Cell Transplant; 2020; 29():963689720958655. PubMed ID: 33086892
[TBL] [Abstract][Full Text] [Related]
6. The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity.
Mellado-Gil JM; Fuente-Martín E; Lorenzo PI; Cobo-Vuilleumier N; López-Noriega L; Martín-Montalvo A; Gómez IGH; Ceballos-Chávez M; Gómez-Jaramillo L; Campos-Caro A; Romero-Zerbo SY; Rodríguez-Comas J; Servitja JM; Rojo-Martinez G; Hmadcha A; Soria B; Bugliani M; Marchetti P; Bérmudez-Silva FJ; Reyes JC; Aguilar-Diosdado M; Gauthier BR
Cell Death Dis; 2018 Feb; 9(3):279. PubMed ID: 29449530
[TBL] [Abstract][Full Text] [Related]
7. Pancreatic and duodenal homeobox protein 1 (Pdx-1) maintains endoplasmic reticulum calcium levels through transcriptional regulation of sarco-endoplasmic reticulum calcium ATPase 2b (SERCA2b) in the islet β cell.
Johnson JS; Kono T; Tong X; Yamamoto WR; Zarain-Herzberg A; Merrins MJ; Satin LS; Gilon P; Evans-Molina C
J Biol Chem; 2014 Nov; 289(47):32798-810. PubMed ID: 25271154
[TBL] [Abstract][Full Text] [Related]
8. The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients.
Marchetti P; Bugliani M; Lupi R; Marselli L; Masini M; Boggi U; Filipponi F; Weir GC; Eizirik DL; Cnop M
Diabetologia; 2007 Dec; 50(12):2486-94. PubMed ID: 17906960
[TBL] [Abstract][Full Text] [Related]
9. Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes.
Laybutt DR; Preston AM; Akerfeldt MC; Kench JG; Busch AK; Biankin AV; Biden TJ
Diabetologia; 2007 Apr; 50(4):752-63. PubMed ID: 17268797
[TBL] [Abstract][Full Text] [Related]
10. Pathological endoplasmic reticulum stress mediated by the IRE1 pathway contributes to pre-insulitic beta cell apoptosis in a virus-induced rat model of type 1 diabetes.
Yang C; Diiorio P; Jurczyk A; O'Sullivan-Murphy B; Urano F; Bortell R
Diabetologia; 2013 Dec; 56(12):2638-46. PubMed ID: 24121653
[TBL] [Abstract][Full Text] [Related]
11. The Orphan Nuclear Receptor NR4A1 Protects Pancreatic β-Cells from Endoplasmic Reticulum (ER) Stress-mediated Apoptosis.
Yu C; Cui S; Zong C; Gao W; Xu T; Gao P; Chen J; Qin D; Guan Q; Liu Y; Fu Y; Li X; Wang X
J Biol Chem; 2015 Aug; 290(34):20687-20699. PubMed ID: 26157144
[TBL] [Abstract][Full Text] [Related]
12. A focus on the role of Pax4 in mature pancreatic islet beta-cell expansion and survival in health and disease.
Brun T; Gauthier BR
J Mol Endocrinol; 2008 Feb; 40(2):37-45. PubMed ID: 18234907
[TBL] [Abstract][Full Text] [Related]
13. Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis.
Riggs AC; Bernal-Mizrachi E; Ohsugi M; Wasson J; Fatrai S; Welling C; Murray J; Schmidt RE; Herrera PL; Permutt MA
Diabetologia; 2005 Nov; 48(11):2313-21. PubMed ID: 16215705
[TBL] [Abstract][Full Text] [Related]
14. WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells.
Yamada T; Ishihara H; Tamura A; Takahashi R; Yamaguchi S; Takei D; Tokita A; Satake C; Tashiro F; Katagiri H; Aburatani H; Miyazaki J; Oka Y
Hum Mol Genet; 2006 May; 15(10):1600-9. PubMed ID: 16571599
[TBL] [Abstract][Full Text] [Related]
15. Pax4 in Health and Diabetes.
Ko J; Fonseca VA; Wu H
Int J Mol Sci; 2023 May; 24(9):. PubMed ID: 37175989
[TBL] [Abstract][Full Text] [Related]
16. Induction of multiple cycles of pancreatic β-cell replacement.
Pfeifer A; Courtney M; Ben-Othman N; Al-Hasani K; Gjernes E; Vieira A; Druelle N; Avolio F; Faurite B; Mansouri A; Collombat P
Cell Cycle; 2013 Oct; 12(20):3243-4. PubMed ID: 24036539
[No Abstract] [Full Text] [Related]
17. PAX4 R192H and P321H polymorphisms in type 2 diabetes and their functional defects.
Sujjitjoon J; Kooptiwut S; Chongjaroen N; Semprasert N; Hanchang W; Chanprasert K; Tangjittipokin W; Yenchitsomanus PT; Plengvidhya N
J Hum Genet; 2016 Nov; 61(11):943-949. PubMed ID: 27334367
[TBL] [Abstract][Full Text] [Related]
18. Both PAX4 and MAFA are expressed in a substantial proportion of normal human pancreatic alpha cells and deregulated in patients with type 2 diabetes.
Bonnavion R; Jaafar R; Kerr-Conte J; Assade F; van Stralen E; Leteurtre E; Pouponnot C; Gargani S; Pattou F; Bertolino P; Cordier-Bussat M; Lu J; Zhang CX
PLoS One; 2013; 8(8):e72194. PubMed ID: 24013263
[TBL] [Abstract][Full Text] [Related]
19. Cross-talk between the unfolded protein response and nuclear factor-κB signalling pathways regulates cytokine-mediated beta cell death in MIN6 cells and isolated mouse islets.
Chan JY; Biden TJ; Laybutt DR
Diabetologia; 2012 Nov; 55(11):2999-3009. PubMed ID: 22893028
[TBL] [Abstract][Full Text] [Related]
20. Sustained production of spliced X-box binding protein 1 (XBP1) induces pancreatic beta cell dysfunction and apoptosis.
Allagnat F; Christulia F; Ortis F; Pirot P; Lortz S; Lenzen S; Eizirik DL; Cardozo AK
Diabetologia; 2010 Jun; 53(6):1120-30. PubMed ID: 20349222
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]