566 related articles for article (PubMed ID: 26816381)
21. KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching.
Zhou D; Liu K; Sun CW; Pawlik KM; Townes TM
Nat Genet; 2010 Sep; 42(9):742-4. PubMed ID: 20676097
[TBL] [Abstract][Full Text] [Related]
22. Epigenetic inactivation of ERF reactivates γ-globin expression in β-thalassemia.
Bao X; Zhang X; Wang L; Wang Z; Huang J; Zhang Q; Ye Y; Liu Y; Chen D; Zuo Y; Liu Q; Xu P; Huang B; Fang J; Lao J; Feng X; Li Y; Kurita R; Nakamura Y; Yu W; Ju C; Huang C; Mohandas N; Li D; Zhao C; Xu X
Am J Hum Genet; 2021 Apr; 108(4):709-721. PubMed ID: 33735615
[TBL] [Abstract][Full Text] [Related]
23. BCL11A-targeted γ-globin gene induction by triterpenoid glycosides of Fagonia indica: A preclinical scientific validation of indigenous herb for the treatment of β-hemoglobinopathies.
Iftikhar F; Khan MBN; Tehreem S; Kanwal N; Musharraf SG
Bioorg Chem; 2023 Nov; 140():106768. PubMed ID: 37586133
[TBL] [Abstract][Full Text] [Related]
24. The Novel Role of the B-Cell Lymphoma/Leukemia 11A (BCL11A) Gene in β-Thalassaemia Treatment.
Mahmoud Ahmed NH; Lai MI
Cardiovasc Hematol Disord Drug Targets; 2023; 22(4):226-236. PubMed ID: 36734897
[TBL] [Abstract][Full Text] [Related]
25. Transcriptional silencing of fetal hemoglobin by BCL11A.
Sankaran VG; Xu J; Orkin SH
Ann N Y Acad Sci; 2010 Aug; 1202():64-8. PubMed ID: 20712774
[TBL] [Abstract][Full Text] [Related]
26. miR-30a regulates γ-globin expression in erythoid precursors of intermedia thalassemia through targeting BCL11A.
Gholampour MA; Asadi M; Naderi M; Azarkeivan A; Soleimani M; Atashi A
Mol Biol Rep; 2020 May; 47(5):3909-3918. PubMed ID: 32406020
[TBL] [Abstract][Full Text] [Related]
27. DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease.
Lettre G; Sankaran VG; Bezerra MA; Araújo AS; Uda M; Sanna S; Cao A; Schlessinger D; Costa FF; Hirschhorn JN; Orkin SH
Proc Natl Acad Sci U S A; 2008 Aug; 105(33):11869-74. PubMed ID: 18667698
[TBL] [Abstract][Full Text] [Related]
28. Genome editing of HBG1 and HBG2 to induce fetal hemoglobin.
Métais JY; Doerfler PA; Mayuranathan T; Bauer DE; Fowler SC; Hsieh MM; Katta V; Keriwala S; Lazzarotto CR; Luk K; Neel MD; Perry SS; Peters ST; Porter SN; Ryu BY; Sharma A; Shea D; Tisdale JF; Uchida N; Wolfe SA; Woodard KJ; Wu Y; Yao Y; Zeng J; Pruett-Miller S; Tsai SQ; Weiss MJ
Blood Adv; 2019 Nov; 3(21):3379-3392. PubMed ID: 31698466
[TBL] [Abstract][Full Text] [Related]
29. Multiple physical stresses induce γ-globin gene expression and fetal hemoglobin production in erythroid cells.
Schaeffer EK; West RJ; Conine SJ; Lowrey CH
Blood Cells Mol Dis; 2014 Apr; 52(4):214-24. PubMed ID: 24314748
[TBL] [Abstract][Full Text] [Related]
30. MBD2a-NuRD binds to the methylated γ-globin gene promoter and uniquely forms a complex required for silencing of HbF expression.
Shang S; Li X; Azzo A; Truong T; Dozmorov M; Lyons C; Manna AK; Williams DC; Ginder GD
Proc Natl Acad Sci U S A; 2023 Jun; 120(25):e2302254120. PubMed ID: 37307480
[TBL] [Abstract][Full Text] [Related]
31. Hemoglobin switching's surprise: the versatile transcription factor BCL11A is a master repressor of fetal hemoglobin.
Bauer DE; Orkin SH
Curr Opin Genet Dev; 2015 Aug; 33():62-70. PubMed ID: 26375765
[TBL] [Abstract][Full Text] [Related]
32. Comparative targeting analysis of KLF1, BCL11A, and HBG1/2 in CD34
Lamsfus-Calle A; Daniel-Moreno A; Antony JS; Epting T; Heumos L; Baskaran P; Admard J; Casadei N; Latifi N; Siegmund DM; Kormann MSD; Handgretinger R; Mezger M
Sci Rep; 2020 Jun; 10(1):10133. PubMed ID: 32576837
[TBL] [Abstract][Full Text] [Related]
33. Acyclovir induces fetal hemoglobin via downregulation of γ-globin repressors, BCL11A and SOX6 trans-acting factors.
Ali H; Khan F; Ghulam Musharraf S
Biochem Pharmacol; 2021 Aug; 190():114612. PubMed ID: 34010599
[TBL] [Abstract][Full Text] [Related]
34. Phenotypic-screening generates active novel fetal globin-inducers that downregulate Bcl11a in a monkey model.
Makino T; Haruyama M; Katayama K; Terashima H; Tsunemi T; Miyazaki K; Terakawa M; Yamashiro K; Yoshioka R; Maeda H
Biochem Pharmacol; 2020 Jan; 171():113717. PubMed ID: 31751536
[TBL] [Abstract][Full Text] [Related]
35. Transcriptional silencing of {gamma}-globin by BCL11A involves long-range interactions and cooperation with SOX6.
Xu J; Sankaran VG; Ni M; Menne TF; Puram RV; Kim W; Orkin SH
Genes Dev; 2010 Apr; 24(8):783-98. PubMed ID: 20395365
[TBL] [Abstract][Full Text] [Related]
36. Highly efficient therapeutic gene editing of human hematopoietic stem cells.
Wu Y; Zeng J; Roscoe BP; Liu P; Yao Q; Lazzarotto CR; Clement K; Cole MA; Luk K; Baricordi C; Shen AH; Ren C; Esrick EB; Manis JP; Dorfman DM; Williams DA; Biffi A; Brugnara C; Biasco L; Brendel C; Pinello L; Tsai SQ; Wolfe SA; Bauer DE
Nat Med; 2019 May; 25(5):776-783. PubMed ID: 30911135
[TBL] [Abstract][Full Text] [Related]
37. Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression.
Topfer SK; Feng R; Huang P; Ly LC; Martyn GE; Blobel GA; Weiss MJ; Quinlan KGR; Crossley M
Blood; 2022 Apr; 139(14):2107-2118. PubMed ID: 35090172
[TBL] [Abstract][Full Text] [Related]
38. SIRT1 activates the expression of fetal hemoglobin genes.
Dai Y; Chen T; Ijaz H; Cho EH; Steinberg MH
Am J Hematol; 2017 Nov; 92(11):1177-1186. PubMed ID: 28776729
[TBL] [Abstract][Full Text] [Related]
39. Pomalidomide reverses γ-globin silencing through the transcriptional reprogramming of adult hematopoietic progenitors.
Dulmovits BM; Appiah-Kubi AO; Papoin J; Hale J; He M; Al-Abed Y; Didier S; Gould M; Husain-Krautter S; Singh SA; Chan KW; Vlachos A; Allen SL; Taylor N; Marambaud P; An X; Gallagher PG; Mohandas N; Lipton JM; Liu JM; Blanc L
Blood; 2016 Mar; 127(11):1481-92. PubMed ID: 26679864
[TBL] [Abstract][Full Text] [Related]
40. Mild dyserythropoiesis and β-like globin gene expression imbalance due to the loss of histone chaperone ASF1B.
Papadopoulos P; Kafasi A; De Cuyper IM; Barroca V; Lewandowski D; Kadri Z; Veldthuis M; Berghuis J; Gillemans N; Benavente Cuesta CM; Grosveld FG; van Zwieten R; Philipsen S; Vernet M; Gutiérrez L; Patrinos GP
Hum Genomics; 2020 Oct; 14(1):39. PubMed ID: 33066815
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
