These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

232 related articles for article (PubMed ID: 26821304)

  • 21. Ability of Bruton's Tyrosine Kinase Inhibitors to Sequester Y551 and Prevent Phosphorylation Determines Potency for Inhibition of Fc Receptor but not B-Cell Receptor Signaling.
    Bender AT; Gardberg A; Pereira A; Johnson T; Wu Y; Grenningloh R; Head J; Morandi F; Haselmayer P; Liu-Bujalski L
    Mol Pharmacol; 2017 Mar; 91(3):208-219. PubMed ID: 28062735
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The role of Bruton's tyrosine kinase in autoimmunity and implications for therapy.
    Crofford LJ; Nyhoff LE; Sheehan JH; Kendall PL
    Expert Rev Clin Immunol; 2016 Jul; 12(7):763-73. PubMed ID: 26864273
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Increased expression of Bruton's tyrosine kinase in peripheral blood is associated with lupus nephritis.
    Kong W; Deng W; Sun Y; Huang S; Zhang Z; Shi B; Chen W; Tang X; Yao G; Feng X; Sun L
    Clin Rheumatol; 2018 Jan; 37(1):43-49. PubMed ID: 28612243
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Bruton's tyrosine kinase and protein kinase C µ are required for TLR7/9-induced IKKα and IRF-1 activation and interferon-β production in conventional dendritic cells.
    Li YF; Lee KG; Ou X; Lam KP
    PLoS One; 2014; 9(8):e105420. PubMed ID: 25170774
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Assessment of the translational value of mouse lupus models using clinically relevant biomarkers.
    Bender AT; Wu Y; Cao Q; Ding Y; Oestreicher J; Genest M; Akare S; Ishizaka ST; Mackey MF
    Transl Res; 2014 Jun; 163(6):515-32. PubMed ID: 24462761
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Evidence for genes in addition to Tlr7 in the Yaa translocation linked with acceleration of systemic lupus erythematosus.
    Santiago-Raber ML; Kikuchi S; Borel P; Uematsu S; Akira S; Kotzin BL; Izui S
    J Immunol; 2008 Jul; 181(2):1556-62. PubMed ID: 18606711
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Requirement of Toll-like receptor 7 for pristane-induced production of autoantibodies and development of murine lupus nephritis.
    Savarese E; Steinberg C; Pawar RD; Reindl W; Akira S; Anders HJ; Krug A
    Arthritis Rheum; 2008 Apr; 58(4):1107-15. PubMed ID: 18383384
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Treatment of lupus-prone mice with a dual inhibitor of TLR7 and TLR9 leads to reduction of autoantibody production and amelioration of disease symptoms.
    Barrat FJ; Meeker T; Chan JH; Guiducci C; Coffman RL
    Eur J Immunol; 2007 Dec; 37(12):3582-6. PubMed ID: 18034431
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Bruton's Tyrosine Kinase, a Component of B Cell Signaling Pathways, Has Multiple Roles in the Pathogenesis of Lupus.
    Satterthwaite AB
    Front Immunol; 2017; 8():1986. PubMed ID: 29403475
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Discovery of Branebrutinib (BMS-986195): A Strategy for Identifying a Highly Potent and Selective Covalent Inhibitor Providing Rapid in Vivo Inactivation of Bruton's Tyrosine Kinase (BTK).
    Watterson SH; Liu Q; Beaudoin Bertrand M; Batt DG; Li L; Pattoli MA; Skala S; Cheng L; Obermeier MT; Moore R; Yang Z; Vickery R; Elzinga PA; Discenza L; D'Arienzo C; Gillooly KM; Taylor TL; Pulicicchio C; Zhang Y; Heimrich E; McIntyre KW; Ruan Q; Westhouse RA; Catlett IM; Zheng N; Chaudhry C; Dai J; Galella MA; Tebben AJ; Pokross M; Li J; Zhao R; Smith D; Rampulla R; Allentoff A; Wallace MA; Mathur A; Salter-Cid L; Macor JE; Carter PH; Fura A; Burke JR; Tino JA
    J Med Chem; 2019 Apr; 62(7):3228-3250. PubMed ID: 30893553
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice.
    Santiago-Raber ML; Dunand-Sauthier I; Wu T; Li QZ; Uematsu S; Akira S; Reith W; Mohan C; Kotzin BL; Izui S
    J Autoimmun; 2010 Jun; 34(4):339-48. PubMed ID: 19944565
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Deletion of the antiphospholipid syndrome autoantigen β2 -glycoprotein I potentiates the lupus autoimmune phenotype in a Toll-like receptor 7-mediated murine model.
    Giannakopoulos B; Mirarabshahi P; Qi M; Weatherall C; Qi JC; Tanaka K; Millar E; Vonthethoff L; Gatto D; Spielman D; Krilis SA
    Arthritis Rheumatol; 2014 Aug; 66(8):2270-80. PubMed ID: 24692206
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Treatment of lupus-prone NZB/NZW F1 mice with recombinant soluble Fc gamma receptor II (CD32).
    Werwitzke S; Trick D; Sondermann P; Kamino K; Schlegelberger B; Kniesch K; Tiede A; Jacob U; Schmidt RE; Witte T
    Ann Rheum Dis; 2008 Feb; 67(2):154-61. PubMed ID: 17557887
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The kinase IRAK4 promotes endosomal TLR and immune complex signaling in B cells and plasmacytoid dendritic cells.
    Corzo CA; Varfolomeev E; Setiadi AF; Francis R; Klabunde S; Senger K; Sujatha-Bhaskar S; Drobnick J; Do S; Suto E; Huang Z; Eastham-Anderson J; Katewa A; Pang J; Domeyer M; Dela Cruz C; Paler-Martinez A; Lau VWC; Hadadianpour A; Ramirez-Carrozi V; Sun Y; Bao K; Xu D; Hunley E; Brightbill HD; Warming S; Roose-Girma M; Wong A; Tam L; Emson CL; Crawford JJ; Young WB; Pappu R; McKenzie BS; Asghari V; Vucic D; Hackney JA; Austin CD; Lee WP; Lekkerkerker A; Ghilardi N; Bryan MC; Kiefer JR; Townsend MJ; Zarrin AA
    Sci Signal; 2020 Jun; 13(634):. PubMed ID: 32487715
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Role of Lgals9 Deficiency in Attenuating Nephritis and Arthritis in BALB/c Mice in a Pristane-Induced Lupus Model.
    Zeggar S; Watanabe KS; Teshigawara S; Hiramatsu S; Katsuyama T; Katsuyama E; Watanabe H; Matsumoto Y; Kawabata T; Sada KE; Niki T; Hirashima M; Wada J
    Arthritis Rheumatol; 2018 Jul; 70(7):1089-1101. PubMed ID: 29481735
    [TBL] [Abstract][Full Text] [Related]  

  • 36. TLR9 and TLR4 are required for the development of autoimmunity and lupus nephritis in pristane nephropathy.
    Summers SA; Hoi A; Steinmetz OM; O'Sullivan KM; Ooi JD; Odobasic D; Akira S; Kitching AR; Holdsworth SR
    J Autoimmun; 2010 Dec; 35(4):291-8. PubMed ID: 20810248
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Induction of autoimmunity by pristane and other naturally occurring hydrocarbons.
    Reeves WH; Lee PY; Weinstein JS; Satoh M; Lu L
    Trends Immunol; 2009 Sep; 30(9):455-64. PubMed ID: 19699150
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Discovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton's Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers.
    Watterson SH; De Lucca GV; Shi Q; Langevine CM; Liu Q; Batt DG; Beaudoin Bertrand M; Gong H; Dai J; Yip S; Li P; Sun D; Wu DR; Wang C; Zhang Y; Traeger SC; Pattoli MA; Skala S; Cheng L; Obermeier MT; Vickery R; Discenza LN; D'Arienzo CJ; Zhang Y; Heimrich E; Gillooly KM; Taylor TL; Pulicicchio C; McIntyre KW; Galella MA; Tebben AJ; Muckelbauer JK; Chang C; Rampulla R; Mathur A; Salter-Cid L; Barrish JC; Carter PH; Fura A; Burke JR; Tino JA
    J Med Chem; 2016 Oct; 59(19):9173-9200. PubMed ID: 27583770
    [TBL] [Abstract][Full Text] [Related]  

  • 39. B-cell subsets, signaling and their roles in secretion of autoantibodies.
    Iwata S; Tanaka Y
    Lupus; 2016 Jul; 25(8):850-6. PubMed ID: 27252261
    [TBL] [Abstract][Full Text] [Related]  

  • 40. TLR7 Protein Expression in Mild and Severe Lupus-Prone Models Is Regulated in a Leukocyte, Genetic, and IRAK4 Dependent Manner.
    Celhar T; Lu HK; Benso L; Rakhilina L; Lee HY; Tripathi S; Zharkova O; Ong WY; Yasuga H; Au B; Marlier D; Lim LHK; Thamboo TP; Mudgett JS; Mackey MF; Zaller DM; Connolly JE; Fairhurst AM
    Front Immunol; 2019; 10():1546. PubMed ID: 31354711
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.