BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 26827136)

  • 1. Synthesis and pharmacological evaluation of trifluoromethyl containing 4-(2-pyrimidinylamino)benzamides as Hedgehog signaling pathway inhibitors.
    Xin M; Zhang L; Wen J; Shen H; Liu Z; Zhao X; Jin Q; Wang M; Cheng L; Huang W; Tang F
    Bioorg Med Chem; 2016 Mar; 24(5):1079-88. PubMed ID: 26827136
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The discovery of novel N-(2-pyrimidinylamino) benzamide derivatives as potent hedgehog signaling pathway inhibitors.
    Xin M; Wen J; Tang F; Tu C; Shen H; Zhao X
    Bioorg Med Chem Lett; 2013 Dec; 23(24):6777-83. PubMed ID: 24176396
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Introduction of fluorine to phenyl group of 4-(2-pyrimidinylamino)benzamides leading to a series of potent hedgehog signaling pathway inhibitors.
    Xin M; Zhang L; Wen J; Shen H; Zhao X; Jin Q; Tang F
    Bioorg Med Chem Lett; 2017 Aug; 27(15):3259-3263. PubMed ID: 28642101
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel 4-(2-pyrimidinylamino)benzamide derivatives as potent hedgehog signaling pathway inhibitors.
    Xin M; Zhang L; Tu C; Tang F; Wen J
    Bioorg Med Chem; 2018 Oct; 26(18):5029-5036. PubMed ID: 30249494
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and evaluation of 4-(2-pyrimidinylamino) benzamides inhibitors of hedgehog signaling pathway.
    Xin M; Wen J; Tang F; Tu C; Huang W; Shen H; Zhao X; Cheng L; Wang M; Zhang L
    Bioorg Med Chem Lett; 2014 Feb; 24(3):983-8. PubMed ID: 24405704
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of novel 4-(2-pyrimidinylamino)benzamide derivatives as highly potent and orally available hedgehog signaling pathway inhibitors.
    Xin M; Zhang L; Jin Q; Tang F; Wen J; Gu L; Cheng L; Zhao Y
    Eur J Med Chem; 2016 Mar; 110():115-25. PubMed ID: 26820554
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis, and evaluation of pyrrolo[2,1-f][1,2,4]triazine derivatives as novel hedgehog signaling pathway inhibitors.
    Xin M; Zhang L; Tang F; Tu C; Wen J; Zhao X; Liu Z; Cheng L; Shen H
    Bioorg Med Chem; 2014 Feb; 22(4):1429-40. PubMed ID: 24486203
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological evaluation of SANT-2 and analogues as inhibitors of the hedgehog signaling pathway.
    Büttner A; Seifert K; Cottin T; Sarli V; Tzagkaroulaki L; Scholz S; Giannis A
    Bioorg Med Chem; 2009 Jul; 17(14):4943-54. PubMed ID: 19541490
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, Synthesis, and Structure-Activity Relationship of Tetrahydropyrido[4,3-d]pyrimidine Derivatives as Potent Smoothened Antagonists with in Vivo Activity.
    Lu W; Liu Y; Ma H; Zheng J; Tian S; Sun Z; Luo L; Li J; Zhang H; Yang ZJ; Zhang X
    ACS Chem Neurosci; 2017 Sep; 8(9):1980-1994. PubMed ID: 28618224
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Five-membered heteroaromatic ring fused-pyrimidine derivatives: design, synthesis, and hedgehog signaling pathway inhibition study.
    Zhang L; Xin M; Shen H; Wen J; Tang F; Tu C; Zhao X; Wei P
    Bioorg Med Chem Lett; 2014 Aug; 24(15):3486-92. PubMed ID: 24923765
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, and biological evaluation of structurally modified isoindolinone and quinazolinone derivatives as hedgehog pathway inhibitors.
    Bhattarai D; Jung JH; Han S; Lee H; Oh SJ; Ko HW; Lee K
    Eur J Med Chem; 2017 Jan; 125():1036-1050. PubMed ID: 27810591
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and Smo Activity of Some Novel Benzamide Derivatives.
    Ding H; Chen K; Song B; Deng C; Li W; Niu L; Bai M; Song H; Zhang L
    Molecules; 2017 Dec; 23(1):. PubMed ID: 29301237
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis, and biological evaluation of optimized phthalazine derivatives as hedgehog signaling pathway inhibitors.
    Lu X; Peng Y; Wang C; Yang J; Bao X; Dong Q; Zhao W; Tan W; Dong X
    Eur J Med Chem; 2017 Sep; 138():384-395. PubMed ID: 28688278
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and Evaluation of Aminothiazole Derivatives as Hedgehog Pathway Inhibitors.
    Sun C; Zhang Y; Lin L; Liu S; Wang R; Zang W; Meng W; Chen X
    Chem Biodivers; 2019 Dec; 16(12):e1900431. PubMed ID: 31609078
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61.
    Calcaterra A; Iovine V; Botta B; Quaglio D; D'Acquarica I; Ciogli A; Iazzetti A; Alfonsi R; Lospinoso Severini L; Infante P; Di Marcotullio L; Mori M; Ghirga F
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):349-358. PubMed ID: 29338454
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and evaluation of novel benzylphthalazine derivatives as hedgehog signaling pathway inhibitors.
    Bao X; Peng Y; Lu X; Yang J; Zhao W; Tan W; Dong X
    Bioorg Med Chem Lett; 2016 Jul; 26(13):3048-3051. PubMed ID: 27180012
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and evaluation of novel dimethylpyridazine derivatives as hedgehog signaling pathway inhibitors.
    Wang C; Zhu M; Lu X; Wang H; Zhao W; Zhang X; Dong X
    Bioorg Med Chem; 2018 Jul; 26(12):3308-3320. PubMed ID: 29739714
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and biological evaluation of novel benzamide derivatives as potent smoothened antagonists.
    Wu TM; Wang DC; Xiang P; Zhang JN; Sang YX; Lin HJ; Chen J; Xie G; Song H; Zhao YL; Xie YM
    Bioorg Med Chem Lett; 2014 Mar; 24(5):1426-31. PubMed ID: 24491459
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phenylaminopyrimidines as inhibitors of Janus kinases (JAKs).
    Burns CJ; Bourke DG; Andrau L; Bu X; Charman SA; Donohue AC; Fantino E; Farrugia M; Feutrill JT; Joffe M; Kling MR; Kurek M; Nero TL; Nguyen T; Palmer JT; Phillips I; Shackleford DM; Sikanyika H; Styles M; Su S; Treutlein H; Zeng J; Wilks AF
    Bioorg Med Chem Lett; 2009 Oct; 19(20):5887-92. PubMed ID: 19762238
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and cytotoxicity studies of Hedgehog enzyme inhibitors SANT-1 and GANT-61 as anticancer agents.
    Chenna V; Hu C; Khan SR
    J Environ Sci Health A Tox Hazard Subst Environ Eng; 2014; 49(6):641-7. PubMed ID: 24521409
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.