574 related articles for article (PubMed ID: 26835873)
1. Iterative design of emetine-based prodrug targeting fibroblast activation protein (FAP) and dipeptidyl peptidase IV DPPIV using a tandem enzymatic activation strategy.
Akinboye ES; Brennen WN; Rosen DM; Bakare O; Denmeade SR
Prostate; 2016 Jun; 76(8):703-14. PubMed ID: 26835873
[TBL] [Abstract][Full Text] [Related]
2. Targeting carcinoma-associated fibroblasts within the tumor stroma with a fibroblast activation protein-activated prodrug.
Brennen WN; Rosen DM; Wang H; Isaacs JT; Denmeade SR
J Natl Cancer Inst; 2012 Sep; 104(17):1320-34. PubMed ID: 22911669
[TBL] [Abstract][Full Text] [Related]
3. Pharmacokinetics and toxicology of a fibroblast activation protein (FAP)-activated prodrug in murine xenograft models of human cancer.
Brennen WN; Rosen DM; Chaux A; Netto GJ; Isaacs JT; Denmeade SR
Prostate; 2014 Sep; 74(13):1308-19. PubMed ID: 25053236
[TBL] [Abstract][Full Text] [Related]
4. Anticancer activities of emetine prodrugs that are proteolytically activated by the prostate specific antigen (PSA) and evaluation of in vivo toxicity of emetine derivatives.
Akinboye ES; Rosen MD; Bakare O; Denmeade SR
Bioorg Med Chem; 2017 Dec; 25(24):6707-6717. PubMed ID: 29153549
[TBL] [Abstract][Full Text] [Related]
5. Increased expression of fibroblast activation protein-alpha in keloid fibroblasts: implications for development of a novel treatment option.
Dienus K; Bayat A; Gilmore BF; Seifert O
Arch Dermatol Res; 2010 Dec; 302(10):725-31. PubMed ID: 20872224
[TBL] [Abstract][Full Text] [Related]
6. Ultrasensitive Fluorescent Probes Reveal an Adverse Action of Dipeptide Peptidase IV and Fibroblast Activation Protein during Proliferation of Cancer Cells.
Gong Q; Shi W; Li L; Wu X; Ma H
Anal Chem; 2016 Aug; 88(16):8309-14. PubMed ID: 27444320
[TBL] [Abstract][Full Text] [Related]
7. Molecular recognition of fibroblast activation protein for diagnostic and therapeutic applications.
Šimková A; Bušek P; Šedo A; Konvalinka J
Biochim Biophys Acta Proteins Proteom; 2020 Jul; 1868(7):140409. PubMed ID: 32171757
[TBL] [Abstract][Full Text] [Related]
8. Targeting the cancer stroma with a fibroblast activation protein-activated promelittin protoxin.
LeBeau AM; Brennen WN; Aggarwal S; Denmeade SR
Mol Cancer Ther; 2009 May; 8(5):1378-86. PubMed ID: 19417147
[TBL] [Abstract][Full Text] [Related]
9. Dipeptidyl peptidase IV as a potential target for selective prodrug activation and chemotherapeutic action in cancers.
Dahan A; Wolk O; Yang P; Mittal S; Wu Z; Landowski CP; Amidon GL
Mol Pharm; 2014 Dec; 11(12):4385-94. PubMed ID: 25365774
[TBL] [Abstract][Full Text] [Related]
10. Acute Ischemic Stroke Severity, Progression, and Outcome Relate to Changes in Dipeptidyl Peptidase IV and Fibroblast Activation Protein Activity.
Baerts L; Brouns R; Kehoe K; Verkerk R; Engelborghs S; De Deyn PP; Hendriks D; De Meester I
Transl Stroke Res; 2017 Apr; 8(2):157-164. PubMed ID: 27561653
[TBL] [Abstract][Full Text] [Related]
11. Role for dipeptidyl peptidase IV in tumor suppression of human non small cell lung carcinoma cells.
Wesley UV; Tiwari S; Houghton AN
Int J Cancer; 2004 May; 109(6):855-66. PubMed ID: 15027119
[TBL] [Abstract][Full Text] [Related]
12. Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers.
Scanlan MJ; Raj BK; Calvo B; Garin-Chesa P; Sanz-Moncasi MP; Healey JH; Old LJ; Rettig WJ
Proc Natl Acad Sci U S A; 1994 Jun; 91(12):5657-61. PubMed ID: 7911242
[TBL] [Abstract][Full Text] [Related]
13. Rationale behind targeting fibroblast activation protein-expressing carcinoma-associated fibroblasts as a novel chemotherapeutic strategy.
Brennen WN; Isaacs JT; Denmeade SR
Mol Cancer Ther; 2012 Feb; 11(2):257-66. PubMed ID: 22323494
[TBL] [Abstract][Full Text] [Related]
14. Fibroblast activation protein-α promotes tumor growth and invasion of breast cancer cells through non-enzymatic functions.
Huang Y; Simms AE; Mazur A; Wang S; León NR; Jones B; Aziz N; Kelly T
Clin Exp Metastasis; 2011 Aug; 28(6):567-79. PubMed ID: 21604185
[TBL] [Abstract][Full Text] [Related]
15. Novel water-soluble prodrugs of acyclovir cleavable by the dipeptidyl-peptidase IV (DPP IV/CD26) enzyme.
Diez-Torrubia A; Cabrera S; de Castro S; García-Aparicio C; Mulder G; De Meester I; Camarasa MJ; Balzarini J; Velázquez S
Eur J Med Chem; 2013; 70():456-68. PubMed ID: 24185376
[TBL] [Abstract][Full Text] [Related]
16. Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8.
Abbott CA; Yu DM; Woollatt E; Sutherland GR; McCaughan GW; Gorrell MD
Eur J Biochem; 2000 Oct; 267(20):6140-50. PubMed ID: 11012666
[TBL] [Abstract][Full Text] [Related]
17. Tumor-targeting efficacy of a BF211 prodrug through hydrolysis by fibroblast activation protein-α.
Chai XP; Sun GL; Fang YF; Hu LH; Liu X; Zhang XW
Acta Pharmacol Sin; 2018 Mar; 39(3):415-424. PubMed ID: 29119969
[TBL] [Abstract][Full Text] [Related]
18. Increased tissue and circulating levels of dipeptidyl peptidase-IV enzymatic activity in patients with pancreatic ductal adenocarcinoma.
Busek P; Vanickova Z; Hrabal P; Brabec M; Fric P; Zavoral M; Skrha J; Kmochova K; Laclav M; Bunganic B; Augustyns K; Van Der Veken P; Sedo A
Pancreatology; 2016; 16(5):829-38. PubMed ID: 27320722
[TBL] [Abstract][Full Text] [Related]
19. Fibroblast activation protein-alpha and dipeptidyl peptidase IV (CD26): cell-surface proteases that activate cell signaling and are potential targets for cancer therapy.
Kelly T
Drug Resist Updat; 2005; 8(1-2):51-8. PubMed ID: 15939342
[TBL] [Abstract][Full Text] [Related]
20. Structural and kinetic analysis of the substrate specificity of human fibroblast activation protein alpha.
Aertgeerts K; Levin I; Shi L; Snell GP; Jennings A; Prasad GS; Zhang Y; Kraus ML; Salakian S; Sridhar V; Wijnands R; Tennant MG
J Biol Chem; 2005 May; 280(20):19441-4. PubMed ID: 15809306
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
