245 related articles for article (PubMed ID: 26838761)
1. An Integrated Approach for Screening and Identification of Positive Allosteric Modulators of N-Methyl-D-Aspartate Receptors.
Jambrina E; Cerne R; Smith E; Scampavia L; Cuadrado M; Findlay J; Krambis MJ; Wakulchik M; Chase P; Brunavs M; Burris KD; Gallagher P; Spicer TP; Ursu D
J Biomol Screen; 2016 Jun; 21(5):468-79. PubMed ID: 26838761
[TBL] [Abstract][Full Text] [Related]
2. Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design.
Volgraf M; Sellers BD; Jiang Y; Wu G; Ly CQ; Villemure E; Pastor RM; Yuen PW; Lu A; Luo X; Liu M; Zhang S; Sun L; Fu Y; Lupardus PJ; Wallweber HJ; Liederer BM; Deshmukh G; Plise E; Tay S; Reynen P; Herrington J; Gustafson A; Liu Y; Dirksen A; Dietz MG; Liu Y; Wang TM; Hanson JE; Hackos D; Scearce-Levie K; Schwarz JB
J Med Chem; 2016 Mar; 59(6):2760-79. PubMed ID: 26919761
[TBL] [Abstract][Full Text] [Related]
3. Enhancing NMDA Receptor Function: Recent Progress on Allosteric Modulators.
Yao L; Zhou Q
Neural Plast; 2017; 2017():2875904. PubMed ID: 28163934
[TBL] [Abstract][Full Text] [Related]
4. Positive allosteric modulation of NMDA receptors: mechanisms, physiological impact and therapeutic potential.
Geoffroy C; Paoletti P; Mony L
J Physiol; 2022 Jan; 600(2):233-259. PubMed ID: 34339523
[TBL] [Abstract][Full Text] [Related]
5. Positive Allosteric Modulation as a Potential Therapeutic Strategy in Anti-NMDA Receptor Encephalitis.
Warikoo N; Brunwasser SJ; Benz A; Shu HJ; Paul SM; Lewis M; Doherty J; Quirk M; Piccio L; Zorumski CF; Day GS; Mennerick S
J Neurosci; 2018 Mar; 38(13):3218-3229. PubMed ID: 29476014
[No Abstract] [Full Text] [Related]
6. A NMDA-receptor calcium influx assay sensitive to stimulation by glutamate and glycine/D-serine.
Guo H; Camargo LM; Yeboah F; Digan ME; Niu H; Pan Y; Reiling S; Soler-Llavina G; Weihofen WA; Wang HR; Shanker YG; Stams T; Bill A
Sci Rep; 2017 Sep; 7(1):11608. PubMed ID: 28912557
[TBL] [Abstract][Full Text] [Related]
7. Identification and characterization of novel NMDA receptor antagonists selective for NR2A- over NR2B-containing receptors.
Bettini E; Sava A; Griffante C; Carignani C; Buson A; Capelli AM; Negri M; Andreetta F; Senar-Sancho SA; Guiral L; Cardullo F
J Pharmacol Exp Ther; 2010 Dec; 335(3):636-44. PubMed ID: 20810618
[TBL] [Abstract][Full Text] [Related]
8. Discovery of Pyrazolo[1,5-a]pyrazin-4-ones as Potent and Brain Penetrant GluN2A-Selective Positive Allosteric Modulators Reducing AMPA Receptor Binding Activity.
Sakurai F; Yukawa T; Kina A; Murakami M; Takami K; Morimoto S; Seto M; Kamata M; Yamashita T; Nakashima K; Narita N; Bettini E; Ugolini A; Corsi M; Hasui T
Bioorg Med Chem; 2022 Feb; 56():116576. PubMed ID: 35051811
[TBL] [Abstract][Full Text] [Related]
9. Mechanism and properties of positive allosteric modulation of N-methyl-d-aspartate receptors by 6-alkyl 2-naphthoic acid derivatives.
Sapkota K; Irvine MW; Fang G; Burnell ES; Bannister N; Volianskis A; Culley GR; Dravid SM; Collingridge GL; Jane DE; Monaghan DT
Neuropharmacology; 2017 Oct; 125():64-79. PubMed ID: 28709671
[TBL] [Abstract][Full Text] [Related]
10. A High-throughput Calcium-flux Assay to Study NMDA-receptors with Sensitivity to Glycine/D-serine and Glutamate.
Yeboah F; Guo H; Bill A
J Vis Exp; 2018 Jul; (137):. PubMed ID: 30059041
[TBL] [Abstract][Full Text] [Related]
11. Biased modulators of NMDA receptors control channel opening and ion selectivity.
Perszyk RE; Swanger SA; Shelley C; Khatri A; Fernandez-Cuervo G; Epplin MP; Zhang J; Le P; Bülow P; Garnier-Amblard E; Gangireddy PKR; Bassell GJ; Yuan H; Menaldino DS; Liotta DC; Liebeskind LS; Traynelis SF
Nat Chem Biol; 2020 Feb; 16(2):188-196. PubMed ID: 31959964
[TBL] [Abstract][Full Text] [Related]
12. Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function.
Hackos DH; Lupardus PJ; Grand T; Chen Y; Wang TM; Reynen P; Gustafson A; Wallweber HJ; Volgraf M; Sellers BD; Schwarz JB; Paoletti P; Sheng M; Zhou Q; Hanson JE
Neuron; 2016 Mar; 89(5):983-99. PubMed ID: 26875626
[TBL] [Abstract][Full Text] [Related]
13. Allosteric modulators of NMDA receptors: multiple sites and mechanisms.
Zhu S; Paoletti P
Curr Opin Pharmacol; 2015 Feb; 20():14-23. PubMed ID: 25462287
[TBL] [Abstract][Full Text] [Related]
14. NMDAR PAMs: Multiple Chemotypes for Multiple Binding Sites.
Goldsmith PJ
Curr Top Med Chem; 2019; 19(24):2239-2253. PubMed ID: 31660834
[TBL] [Abstract][Full Text] [Related]
15. Whole-cell patch-clamp analysis of recombinant NMDA receptor pharmacology using brief glutamate applications.
Glasgow NG; Johnson JW
Methods Mol Biol; 2014; 1183():23-41. PubMed ID: 25023300
[TBL] [Abstract][Full Text] [Related]
16. Biased mGlu5-Positive Allosteric Modulators Provide In Vivo Efficacy without Potentiating mGlu5 Modulation of NMDAR Currents.
Rook JM; Xiang Z; Lv X; Ghoshal A; Dickerson JW; Bridges TM; Johnson KA; Foster DJ; Gregory KJ; Vinson PN; Thompson AD; Byun N; Collier RL; Bubser M; Nedelcovych MT; Gould RW; Stauffer SR; Daniels JS; Niswender CM; Lavreysen H; Mackie C; Conde-Ceide S; Alcazar J; Bartolomé-Nebreda JM; Macdonald GJ; Talpos JC; Steckler T; Jones CK; Lindsley CW; Conn PJ
Neuron; 2015 May; 86(4):1029-1040. PubMed ID: 25937172
[TBL] [Abstract][Full Text] [Related]
17. Investigation of the structural requirements for N-methyl-D-aspartate receptor positive and negative allosteric modulators based on 2-naphthoic acid.
Irvine MW; Fang G; Sapkota K; Burnell ES; Volianskis A; Costa BM; Culley G; Collingridge GL; Monaghan DT; Jane DE
Eur J Med Chem; 2019 Feb; 164():471-498. PubMed ID: 30622023
[TBL] [Abstract][Full Text] [Related]
18. Role of mGlu
Ghoshal A; Moran SP; Dickerson JW; Joffe ME; Grueter BA; Xiang Z; Lindsley CW; Rook JM; Conn PJ
ACS Chem Neurosci; 2017 Oct; 8(10):2254-2265. PubMed ID: 28679049
[TBL] [Abstract][Full Text] [Related]
19. High-Throughput Screen of GluK1 Receptor Identifies Selective Inhibitors with a Variety of Kinetic Profiles Using Fluorescence and Electrophysiology Assays.
Solly K; Klein R; Rudd M; Holloway MK; Johnson EN; Henze D; Finley MF
J Biomol Screen; 2015 Jul; 20(6):708-19. PubMed ID: 25700884
[TBL] [Abstract][Full Text] [Related]
20. N-aryl piperazine metabotropic glutamate receptor 5 positive allosteric modulators possess efficacy in preclinical models of NMDA hypofunction and cognitive enhancement.
Gregory KJ; Herman EJ; Ramsey AJ; Hammond AS; Byun NE; Stauffer SR; Manka JT; Jadhav S; Bridges TM; Weaver CD; Niswender CM; Steckler T; Drinkenburg WH; Ahnaou A; Lavreysen H; Macdonald GJ; Bartolomé JM; Mackie C; Hrupka BJ; Caron MG; Daigle TL; Lindsley CW; Conn PJ; Jones CK
J Pharmacol Exp Ther; 2013 Nov; 347(2):438-57. PubMed ID: 23965381
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]