BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

252 related articles for article (PubMed ID: 26841847)

  • 1. MicroRNA-101 targets von Hippel-Lindau tumor suppressor (VHL) to induce HIF1α mediated apoptosis and cell cycle arrest in normoxia condition.
    Liu N; Xia WY; Liu SS; Chen HY; Sun L; Liu MY; Li LF; Lu HM; Fu YJ; Wang P; Wu H; Gao JX
    Sci Rep; 2016 Feb; 6():20489. PubMed ID: 26841847
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutant versions of von Hippel-Lindau (VHL) can protect HIF1α from SART1-mediated degradation in clear-cell renal cell carcinoma.
    Ordóñez-Navadijo Á; Fuertes-Yebra E; Acosta-Iborra B; Balsa E; Elorza A; Aragonés J; Landazuri MO
    Oncogene; 2016 Feb; 35(5):587-94. PubMed ID: 25915846
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inactivation of von Hippel-Lindau increases ovarian cancer cell aggressiveness through the HIF1α/miR-210/VMP1 signaling pathway.
    Liu T; Zhao L; Chen W; Li Z; Hou H; Ding L; Li X
    Int J Mol Med; 2014 May; 33(5):1236-42. PubMed ID: 24549370
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MicroRNA-185 inhibits cell proliferation and induces cell apoptosis by targeting VEGFA directly in von Hippel-Lindau-inactivated clear cell renal cell carcinoma.
    Ma X; Shen D; Li H; Zhang Y; Lv X; Huang Q; Gao Y; Li X; Gu L; Xiu S; Bao X; Duan J; Zhang X
    Urol Oncol; 2015 Apr; 33(4):169.e1-11. PubMed ID: 25700976
    [TBL] [Abstract][Full Text] [Related]  

  • 5. microRNA-222-Mediated VHL Downregulation Facilitates Retinoblastoma Chemoresistance by Increasing HIF1α Expression.
    Li C; Zhao J; Sun W
    Invest Ophthalmol Vis Sci; 2020 Aug; 61(10):9. PubMed ID: 32756923
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of VHL, HIF1A and SDH on the expression of miR-210: Implications for tumoral pseudo-hypoxic fate.
    Merlo A; Bernardo-Castiñeira C; Sáenz-de-Santa-María I; Pitiot AS; Balbín M; Astudillo A; Valdés N; Scola B; Del Toro R; Méndez-Ferrer S; Piruat JI; Suarez C; Chiara MD
    Oncotarget; 2017 Jan; 8(4):6700-6717. PubMed ID: 28036268
    [TBL] [Abstract][Full Text] [Related]  

  • 7. hsa-miR-210 Is induced by hypoxia and is an independent prognostic factor in breast cancer.
    Camps C; Buffa FM; Colella S; Moore J; Sotiriou C; Sheldon H; Harris AL; Gleadle JM; Ragoussis J
    Clin Cancer Res; 2008 Mar; 14(5):1340-8. PubMed ID: 18316553
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MicroRNA-135b-5p promotes endothelial cell proliferation and angiogenesis in diabetic retinopathy mice by inhibiting Von Hipp-el-Lindau and elevating hypoxia inducible factor α expression.
    Liu L; Xu H; Zhao H; Sui D
    J Drug Target; 2021 Mar; 29(3):300-309. PubMed ID: 33032456
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
    Carroll VA; Ashcroft M
    Cancer Res; 2006 Jun; 66(12):6264-70. PubMed ID: 16778202
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pleiotropic action of renal cell carcinoma-dysregulated miRNAs on hypoxia-related signaling pathways.
    Lichner Z; Mejia-Guerrero S; Ignacak M; Krizova A; Bao TT; Girgis AH; Youssef YM; Yousef GM
    Am J Pathol; 2012 Apr; 180(4):1675-87. PubMed ID: 22326755
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Formation of Renal Cysts and Tumors in Vhl/Trp53-Deficient Mice Requires HIF1α and HIF2α.
    Schönenberger D; Harlander S; Rajski M; Jacobs RA; Lundby AK; Adlesic M; Hejhal T; Wild PJ; Lundby C; Frew IJ
    Cancer Res; 2016 Apr; 76(7):2025-36. PubMed ID: 26759234
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutations of the von Hippel-Lindau gene confer increased susceptibility to natural killer cells of clear-cell renal cell carcinoma.
    Perier A; Fregni G; Wittnebel S; Gad S; Allard M; Gervois N; Escudier B; Azzarone B; Caignard A
    Oncogene; 2011 Jun; 30(23):2622-32. PubMed ID: 21258414
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Overexpression of von Hippel-Lindau protein synergizes with doxorubicin to suppress hepatocellular carcinoma in mice.
    Wang J; Ma Y; Jiang H; Zhu H; Liu L; Sun B; Pan S; Krissansen GW; Sun X
    J Hepatol; 2011 Aug; 55(2):359-68. PubMed ID: 21168458
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanism of hypoxia-specific cytotoxicity of procaspase-3 fused with a VHL-mediated protein destruction motif of HIF-1alpha containing Pro564.
    Harada H; Kizaka-Kondoh S; Hiraoka M
    FEBS Lett; 2006 Oct; 580(24):5718-22. PubMed ID: 17010341
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The expression of the von Hippel-Lindau gene product and its impact on invasiveness of human breast cancer cells.
    Zia MK; Rmali KA; Watkins G; Mansel RE; Jiang WG
    Int J Mol Med; 2007 Oct; 20(4):605-11. PubMed ID: 17786294
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NF-kappaB-dependent plasticity of the epithelial to mesenchymal transition induced by Von Hippel-Lindau inactivation in renal cell carcinomas.
    Pantuck AJ; An J; Liu H; Rettig MB
    Cancer Res; 2010 Jan; 70(2):752-61. PubMed ID: 20068166
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hypoxia mediated expression of stem cell markers in VHL-associated hemangioblastomas.
    Ponnaluri VK; Vavilala DT; Prakash S; Mukherji M
    Biochem Biophys Res Commun; 2013 Aug; 438(1):71-7. PubMed ID: 23872148
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MicroRNA-224 Promotes Pancreatic Cancer Cell Proliferation and Migration by Targeting the TXNIP-Mediated HIF1α Pathway.
    Zhu G; Zhou L; Liu H; Shan Y; Zhang X
    Cell Physiol Biochem; 2018; 48(4):1735-1746. PubMed ID: 30078003
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hypoxia-driven osteopontin contributes to breast tumor growth through modulation of HIF1α-mediated VEGF-dependent angiogenesis.
    Raja R; Kale S; Thorat D; Soundararajan G; Lohite K; Mane A; Karnik S; Kundu GC
    Oncogene; 2014 Apr; 33(16):2053-64. PubMed ID: 23728336
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of Rac1 and Cdc42 in hypoxia induced p53 and von Hippel-Lindau suppression and HIF1alpha activation.
    Xue Y; Bi F; Zhang X; Zhang S; Pan Y; Liu N; Shi Y; Yao X; Zheng Y; Fan D
    Int J Cancer; 2006 Jun; 118(12):2965-72. PubMed ID: 16395716
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.