BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

286 related articles for article (PubMed ID: 26843189)

  • 1. MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancers harboring EGFR extracellular domain mutations.
    Arena S; Siravegna G; Mussolin B; Kearns JD; Wolf BB; Misale S; Lazzari L; Bertotti A; Trusolino L; Adjei AA; Montagut C; Di Nicolantonio F; Nering R; Bardelli A
    Sci Transl Med; 2016 Feb; 8(324):324ra14. PubMed ID: 26843189
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The First-in-class Anti-EGFR Antibody Mixture Sym004 Overcomes Cetuximab Resistance Mediated by EGFR Extracellular Domain Mutations in Colorectal Cancer.
    Sánchez-Martín FJ; Bellosillo B; Gelabert-Baldrich M; Dalmases A; Cañadas I; Vidal J; Martinez A; Argilés G; Siravegna G; Arena S; Koefoed K; Visa L; Arpí O; Horak ID; Iglesias M; Stroh C; Kragh M; Rovira A; Albanell J; Tabernero J; Bardelli A; Montagut C
    Clin Cancer Res; 2016 Jul; 22(13):3260-7. PubMed ID: 26888827
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The genomic landscape of response to EGFR blockade in colorectal cancer.
    Bertotti A; Papp E; Jones S; Adleff V; Anagnostou V; Lupo B; Sausen M; Phallen J; Hruban CA; Tokheim C; Niknafs N; Nesselbush M; Lytle K; Sassi F; Cottino F; Migliardi G; Zanella ER; Ribero D; Russolillo N; Mellano A; Muratore A; Paraluppi G; Salizzoni M; Marsoni S; Kragh M; Lantto J; Cassingena A; Li QK; Karchin R; Scharpf R; Sartore-Bianchi A; Siena S; Diaz LA; Trusolino L; Velculescu VE
    Nature; 2015 Oct; 526(7572):263-7. PubMed ID: 26416732
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Acquired RAS or EGFR mutations and duration of response to EGFR blockade in colorectal cancer.
    Van Emburgh BO; Arena S; Siravegna G; Lazzari L; Crisafulli G; Corti G; Mussolin B; Baldi F; Buscarino M; Bartolini A; Valtorta E; Vidal J; Bellosillo B; Germano G; Pietrantonio F; Ponzetti A; Albanell J; Siena S; Sartore-Bianchi A; Di Nicolantonio F; Montagut C; Bardelli A
    Nat Commun; 2016 Dec; 7():13665. PubMed ID: 27929064
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients.
    Siravegna G; Mussolin B; Buscarino M; Corti G; Cassingena A; Crisafulli G; Ponzetti A; Cremolini C; Amatu A; Lauricella C; Lamba S; Hobor S; Avallone A; Valtorta E; Rospo G; Medico E; Motta V; Antoniotti C; Tatangelo F; Bellosillo B; Veronese S; Budillon A; Montagut C; Racca P; Marsoni S; Falcone A; Corcoran RB; Di Nicolantonio F; Loupakis F; Siena S; Sartore-Bianchi A; Bardelli A
    Nat Med; 2015 Jul; 21(7):795-801. PubMed ID: 26030179
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer.
    Braig F; März M; Schieferdecker A; Schulte A; Voigt M; Stein A; Grob T; Alawi M; Indenbirken D; Kriegs M; Engel E; Vanhoefer U; Grundhoff A; Loges S; Riecken K; Fehse B; Bokemeyer C; Binder M
    Oncotarget; 2015 May; 6(14):12035-47. PubMed ID: 26059438
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TGFα and amphiregulin paracrine network promotes resistance to EGFR blockade in colorectal cancer cells.
    Hobor S; Van Emburgh BO; Crowley E; Misale S; Di Nicolantonio F; Bardelli A
    Clin Cancer Res; 2014 Dec; 20(24):6429-38. PubMed ID: 24916700
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ATM mutations and E-cadherin expression define sensitivity to EGFR-targeted therapy in colorectal cancer.
    Geißler AL; Geißler M; Kottmann D; Lutz L; Fichter CD; Fritsch R; Weddeling B; Makowiec F; Werner M; Lassmann S
    Oncotarget; 2017 Mar; 8(10):17164-17190. PubMed ID: 28199979
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Clinical relevance of EGFR- and KRAS-status in colorectal cancer patients treated with monoclonal antibodies directed against the EGFR.
    Heinemann V; Stintzing S; Kirchner T; Boeck S; Jung A
    Cancer Treat Rev; 2009 May; 35(3):262-71. PubMed ID: 19117687
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Blockade of EGFR and MEK intercepts heterogeneous mechanisms of acquired resistance to anti-EGFR therapies in colorectal cancer.
    Misale S; Arena S; Lamba S; Siravegna G; Lallo A; Hobor S; Russo M; Buscarino M; Lazzari L; Sartore-Bianchi A; Bencardino K; Amatu A; Lauricella C; Valtorta E; Siena S; Di Nicolantonio F; Bardelli A
    Sci Transl Med; 2014 Feb; 6(224):224ra26. PubMed ID: 24553387
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies.
    Sartore-Bianchi A; Martini M; Molinari F; Veronese S; Nichelatti M; Artale S; Di Nicolantonio F; Saletti P; De Dosso S; Mazzucchelli L; Frattini M; Siena S; Bardelli A
    Cancer Res; 2009 Mar; 69(5):1851-7. PubMed ID: 19223544
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Emergence of Multiple EGFR Extracellular Mutations during Cetuximab Treatment in Colorectal Cancer.
    Arena S; Bellosillo B; Siravegna G; Martínez A; Cañadas I; Lazzari L; Ferruz N; Russo M; Misale S; González I; Iglesias M; Gavilan E; Corti G; Hobor S; Crisafulli G; Salido M; Sánchez J; Dalmases A; Bellmunt J; De Fabritiis G; Rovira A; Di Nicolantonio F; Albanell J; Bardelli A; Montagut C
    Clin Cancer Res; 2015 May; 21(9):2157-66. PubMed ID: 25623215
    [TBL] [Abstract][Full Text] [Related]  

  • 13. HER2 genomic amplification in circulating tumor DNA from patients with cetuximab-resistant colorectal cancer.
    Takegawa N; Yonesaka K; Sakai K; Ueda H; Watanabe S; Nonagase Y; Okuno T; Takeda M; Maenishi O; Tsurutani J; Satoh T; Okamoto I; Nishio K; Tamura T; Nakagawa K
    Oncotarget; 2016 Jan; 7(3):3453-60. PubMed ID: 26657506
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanisms of resistance to anti-EGFR therapy in colorectal cancer.
    Zhao B; Wang L; Qiu H; Zhang M; Sun L; Peng P; Yu Q; Yuan X
    Oncotarget; 2017 Jan; 8(3):3980-4000. PubMed ID: 28002810
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nanobody Targeting of Epidermal Growth Factor Receptor (EGFR) Ectodomain Variants Overcomes Resistance to Therapeutic EGFR Antibodies.
    Tintelnot J; Baum N; Schultheiß C; Braig F; Trentmann M; Finter J; Fumey W; Bannas P; Fehse B; Riecken K; Schuetze K; Bokemeyer C; Rösner T; Valerius T; Peipp M; Koch-Nolte F; Binder M
    Mol Cancer Ther; 2019 Apr; 18(4):823-833. PubMed ID: 30824613
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers.
    Diaz LA; Williams RT; Wu J; Kinde I; Hecht JR; Berlin J; Allen B; Bozic I; Reiter JG; Nowak MA; Kinzler KW; Oliner KS; Vogelstein B
    Nature; 2012 Jun; 486(7404):537-40. PubMed ID: 22722843
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Frequency of S492R mutations in the epidermal growth factor receptor: analysis of plasma DNA from patients with metastatic colorectal cancer treated with panitumumab or cetuximab monotherapy.
    Price T; Ang A; Boedigheimer M; Kim TW; Li J; Cascinu S; Ruff P; Satya Suresh A; Thomas A; Tjulandin S; Peeters M
    Cancer Biol Ther; 2020 Oct; 21(10):891-898. PubMed ID: 33026965
    [TBL] [Abstract][Full Text] [Related]  

  • 18. New findings on primary and acquired resistance to anti-EGFR therapy in metastatic colorectal cancer: do all roads lead to RAS?
    Bronte G; Silvestris N; Castiglia M; Galvano A; Passiglia F; Sortino G; Cicero G; Rolfo C; Peeters M; Bazan V; Fanale D; Giordano A; Russo A
    Oncotarget; 2015 Sep; 6(28):24780-96. PubMed ID: 26318427
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer.
    Di Nicolantonio F; Martini M; Molinari F; Sartore-Bianchi A; Arena S; Saletti P; De Dosso S; Mazzucchelli L; Frattini M; Siena S; Bardelli A
    J Clin Oncol; 2008 Dec; 26(35):5705-12. PubMed ID: 19001320
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of a mutation in the extracellular domain of the Epidermal Growth Factor Receptor conferring cetuximab resistance in colorectal cancer.
    Montagut C; Dalmases A; Bellosillo B; Crespo M; Pairet S; Iglesias M; Salido M; Gallen M; Marsters S; Tsai SP; Minoche A; Seshagiri S; Serrano S; Himmelbauer H; Bellmunt J; Rovira A; Settleman J; Bosch F; Albanell J
    Nat Med; 2012 Jan; 18(2):221-3. PubMed ID: 22270724
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.