201 related articles for article (PubMed ID: 26843621)
1. The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint.
Di Magno L; Basile A; Coni S; Manni S; Sdruscia G; D'Amico D; Antonucci L; Infante P; De Smaele E; Cucchi D; Ferretti E; Di Marcotullio L; Screpanti I; Canettieri G
Oncotarget; 2016 Feb; 7(8):9538-49. PubMed ID: 26843621
[TBL] [Abstract][Full Text] [Related]
2. Non-canonical Hedgehog/AMPK-Mediated Control of Polyamine Metabolism Supports Neuronal and Medulloblastoma Cell Growth.
D'Amico D; Antonucci L; Di Magno L; Coni S; Sdruscia G; Macone A; Miele E; Infante P; Di Marcotullio L; De Smaele E; Ferretti E; Ciapponi L; Giangaspero F; Yates JR; Agostinelli E; Cardinali B; Screpanti I; Gulino A; Canettieri G
Dev Cell; 2015 Oct; 35(1):21-35. PubMed ID: 26460945
[TBL] [Abstract][Full Text] [Related]
3. β-Catenin-Gli1 interaction regulates proliferation and tumor growth in medulloblastoma.
Zinke J; Schneider FT; Harter PN; Thom S; Ziegler N; Toftgård R; Plate KH; Liebner S
Mol Cancer; 2015 Feb; 14(1):17. PubMed ID: 25645196
[TBL] [Abstract][Full Text] [Related]
4. AMP-Activated Protein Kinase Directly Phosphorylates and Destabilizes Hedgehog Pathway Transcription Factor GLI1 in Medulloblastoma.
Li YH; Luo J; Mosley YY; Hedrick VE; Paul LN; Chang J; Zhang G; Wang YK; Banko MR; Brunet A; Kuang S; Wu JL; Chang CJ; Scott MP; Yang JY
Cell Rep; 2015 Jul; 12(4):599-609. PubMed ID: 26190112
[TBL] [Abstract][Full Text] [Related]
5. Dual degradation signals destruct GLI1: AMPK inhibits GLI1 through β-TrCP-mediated proteasome degradation.
Zhang R; Huang SY; Ka-Wai Li K; Li YH; Hsu WH; Zhang GJ; Chang CJ; Yang JY
Oncotarget; 2017 Jul; 8(30):49869-49881. PubMed ID: 28562331
[TBL] [Abstract][Full Text] [Related]
6. Synergism between Hedgehog-GLI and EGFR signaling in Hedgehog-responsive human medulloblastoma cells induces downregulation of canonical Hedgehog-target genes and stabilized expression of GLI1.
Götschel F; Berg D; Gruber W; Bender C; Eberl M; Friedel M; Sonntag J; Rüngeler E; Hache H; Wierling C; Nietfeld W; Lehrach H; Frischauf A; Schwartz-Albiez R; Aberger F; Korf U
PLoS One; 2013; 8(6):e65403. PubMed ID: 23762360
[TBL] [Abstract][Full Text] [Related]
7. MEKK2 and MEKK3 suppress Hedgehog pathway-dependent medulloblastoma by inhibiting GLI1 function.
Lu J; Liu L; Zheng M; Li X; Wu A; Wu Q; Liao C; Zou J; Song H
Oncogene; 2018 Jul; 37(28):3864-3878. PubMed ID: 29662197
[TBL] [Abstract][Full Text] [Related]
8. RNA editing of the GLI1 transcription factor modulates the output of Hedgehog signaling.
Shimokawa T; Rahman MF; Tostar U; Sonkoly E; Ståhle M; Pivarcsi A; Palaniswamy R; Zaphiropoulos PG
RNA Biol; 2013 Feb; 10(2):321-33. PubMed ID: 23324600
[TBL] [Abstract][Full Text] [Related]
9. CAT3, a novel agent for medulloblastoma and glioblastoma treatment, inhibits tumor growth by disrupting the Hedgehog signaling pathway.
Chen J; Lv H; Hu J; Ji M; Xue N; Li C; Ma S; Zhou Q; Lin B; Li Y; Yu S; Chen X
Cancer Lett; 2016 Oct; 381(2):391-403. PubMed ID: 27495899
[TBL] [Abstract][Full Text] [Related]
10. The Plk1 kinase negatively regulates the Hedgehog signaling pathway by phosphorylating Gli1.
Zhang T; Xin G; Jia M; Zhuang T; Zhu S; Zhang B; Wang G; Jiang Q; Zhang C
J Cell Sci; 2019 Jan; 132(2):. PubMed ID: 30578313
[TBL] [Abstract][Full Text] [Related]
11. Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation.
Antonucci L; Di Magno L; D'Amico D; Manni S; Serrao SM; Di Pastena F; Bordone R; Yurtsever ZN; Caimano M; Petroni M; Giorgi A; Schininà ME; Yates Iii JR; Di Marcotullio L; De Smaele E; Checquolo S; Capalbo C; Agostinelli E; Maroder M; Coni S; Canettieri G
Int J Oncol; 2019 Feb; 54(2):505-514. PubMed ID: 30483764
[TBL] [Abstract][Full Text] [Related]
12. Loss of Pin1 Suppresses Hedgehog-Driven Medulloblastoma Tumorigenesis.
Xu T; Zhang H; Park SS; Venneti S; Kuick R; Ha K; Michael LE; Santi M; Uchida C; Uchida T; Srinivasan A; Olson JM; Dlugosz AA; Camelo-Piragua S; Rual JF
Neoplasia; 2017 Mar; 19(3):216-225. PubMed ID: 28167297
[TBL] [Abstract][Full Text] [Related]
13. RITA downregulates Hedgehog-GLI in medulloblastoma and rhabdomyosarcoma via JNK-dependent but p53-independent mechanism.
Azatyan A; Gallo-Oller G; Diao Y; Selivanova G; Johnsen JI; Zaphiropoulos PG
Cancer Lett; 2019 Feb; 442():341-350. PubMed ID: 30447254
[TBL] [Abstract][Full Text] [Related]
14. Responsiveness to Hedgehog Pathway Inhibitors in T-Cell Acute Lymphoblastic Leukemia Cells Is Highly Dependent on 5'AMP-Activated Kinase Inactivation.
Tosello V; Bongiovanni D; Di Martino L; Franchin C; Zanovello P; Arrigoni G; Piovan E
Int J Mol Sci; 2021 Jun; 22(12):. PubMed ID: 34203724
[TBL] [Abstract][Full Text] [Related]
15. Hedgehog signaling negatively co-regulates BH3-only protein Noxa and TAp73 in TP53-mutated cells.
Meister MT; Boedicker C; Klingebiel T; Fulda S
Cancer Lett; 2018 Aug; 429():19-28. PubMed ID: 29702195
[TBL] [Abstract][Full Text] [Related]
16. Hedgehog signaling promotes medulloblastoma survival via Bc/II.
Bar EE; Chaudhry A; Farah MH; Eberhart CG
Am J Pathol; 2007 Jan; 170(1):347-55. PubMed ID: 17200206
[TBL] [Abstract][Full Text] [Related]
17. Phosphorylation of human glioma-associated oncogene 1 on Ser937 regulates Sonic Hedgehog signaling in medulloblastoma.
Zeng LH; Tang C; Yao M; He Q; Qv M; Ren Q; Xu Y; Shen T; Gu W; Xu C; Zou C; Ji X; Wu X; Wang J
Nat Commun; 2024 Feb; 15(1):987. PubMed ID: 38307877
[TBL] [Abstract][Full Text] [Related]
18. Druggable glycolytic requirement for Hedgehog-dependent neuronal and medulloblastoma growth.
Di Magno L; Manzi D; D'Amico D; Coni S; Macone A; Infante P; Di Marcotullio L; De Smaele E; Ferretti E; Screpanti I; Agostinelli E; Gulino A; Canettieri G
Cell Cycle; 2014; 13(21):3404-13. PubMed ID: 25485584
[TBL] [Abstract][Full Text] [Related]
19. Identification of novel GLI1 target genes and regulatory circuits in human cancer cells.
Diao Y; Rahman MF; Vyatkin Y; Azatyan A; St Laurent G; Kapranov P; Zaphiropoulos PG
Mol Oncol; 2018 Oct; 12(10):1718-1734. PubMed ID: 30098229
[TBL] [Abstract][Full Text] [Related]
20. DeSUMOylation of Gli1 by SENP1 Attenuates Sonic Hedgehog Signaling.
Liu H; Yan S; Ding J; Yu TT; Cheng SY
Mol Cell Biol; 2017 Sep; 37(18):. PubMed ID: 28630282
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]