These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

104 related articles for article (PubMed ID: 26845138)

  • 1. Synthesis of Combretastatin A-4 Analogs and their Biological Activities.
    Siebert A; Gensicka M; Cholewinski G; Dzierzbicka K
    Anticancer Agents Med Chem; 2016; 16(8):942-960. PubMed ID: 26845138
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel cis-restricted β-lactam combretastatin A-4 analogues display anti-vascular and anti-metastatic properties in vitro.
    Nathwani SM; Hughes L; Greene LM; Carr M; O'Boyle NM; McDonnell S; Meegan MJ; Zisterer DM
    Oncol Rep; 2013 Feb; 29(2):585-94. PubMed ID: 23232969
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Abilities of 3,4-diarylfuran-2-one analogs of combretastatin A-4 to inhibit both proliferation of tumor cell lines and growth of relevant tumors in nude mice.
    Sun L; Vasilevich NI; Fuselier JA; Coy DH
    Anticancer Res; 2004; 24(1):179-86. PubMed ID: 15015595
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design and synthesis of 3,5-disubstituted boron-containing 1,2,4-oxadiazoles as potential combretastatin A-4 (CA-4) analogs.
    Das BC; Tang XY; Rogler P; Evans T
    Tetrahedron Lett; 2012 Aug; 53(31):3947-3950. PubMed ID: 24039307
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and biological evaluation of cis-restricted triazole/tetrazole mimics of combretastatin-benzothiazole hybrids as tubulin polymerization inhibitors and apoptosis inducers.
    Subba Rao AV; Swapna K; Shaik SP; Lakshma Nayak V; Srinivasa Reddy T; Sunkari S; Shaik TB; Bagul C; Kamal A
    Bioorg Med Chem; 2017 Feb; 25(3):977-999. PubMed ID: 28034647
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Advances in antitumor research of CA-4 analogs carrying quinoline scaffold.
    Wang C; Chang J; Yang S; Shi L; Zhang Y; Liu W; Meng J; Zeng J; Zhang R; Xing D
    Front Chem; 2022; 10():1040333. PubMed ID: 36385996
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study.
    Lin CM; Singh SB; Chu PS; Dempcy RO; Schmidt JM; Pettit GR; Hamel E
    Mol Pharmacol; 1988 Aug; 34(2):200-8. PubMed ID: 3412321
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The vascular targeting agent combretastatin-A4 and a novel cis-Restricted {beta}-Lactam Analogue, CA-432, induce apoptosis in human chronic myeloid leukemia cells and ex vivo patient samples including those displaying multidrug resistance.
    Greene LM; Nathwani SM; Bright SA; Fayne D; Croke A; Gagliardi M; McElligott AM; O'Connor L; Carr M; Keely NO; O'Boyle NM; Carroll P; Sarkadi B; Conneally E; Lloyd DG; Lawler M; Meegan MJ; Zisterer DM
    J Pharmacol Exp Ther; 2010 Nov; 335(2):302-13. PubMed ID: 20699436
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design and synthesis of silicon-containing tubulin polymerization inhibitors: replacement of the ethylene moiety of combretastatin A-4 with a silicon linker.
    Nakamura M; Kajita D; Matsumoto Y; Hashimoto Y
    Bioorg Med Chem; 2013 Dec; 21(23):7381-91. PubMed ID: 24139940
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and cytotoxic activity of certain trisubstituted azetidin-2-one derivatives as a cis-restricted combretastatin A-4 analogues.
    Elmeligie S; Taher AT; Khalil NA; El-Said AH
    Arch Pharm Res; 2017 Jan; 40(1):13-24. PubMed ID: 27747473
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 3-(3,4,5-Trimethoxyphenylselenyl)-1H-indoles and their selenoxides as combretastatin A-4 analogs: microwave-assisted synthesis and biological evaluation.
    Wen Z; Xu J; Wang Z; Qi H; Xu Q; Bai Z; Zhang Q; Bao K; Wu Y; Zhang W
    Eur J Med Chem; 2015 Jan; 90():184-94. PubMed ID: 25461319
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Computational Design and Synthesis of Novel Fluoro-Analogs of Combretastatins A-4 and A-1.
    Zong Y; Shea C; Maffucci K; Ojima I
    J Fluor Chem; 2017 Nov; 203():193-199. PubMed ID: 29311752
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design of combretastatin A-4 analogs as tubulin targeted vascular disrupting agent with special emphasis on their cis-restricted isomers.
    Rajak H; Dewangan PK; Patel V; Jain DK; Singh A; Veerasamy R; Sharma PC; Dixit A
    Curr Pharm Des; 2013; 19(10):1923-55. PubMed ID: 23237054
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
    Stefański T; Mikstacka R; Kurczab R; Dutkiewicz Z; Kucińska M; Murias M; Zielińska-Przyjemska M; Cichocki M; Teubert A; Kaczmarek M; Hogendorf A; Sobiak S
    Eur J Med Chem; 2018 Jan; 144():797-816. PubMed ID: 29291446
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Combretazet-3 a novel synthetic cis-stable combretastatin A-4-azetidinone hybrid with enhanced stability and therapeutic efficacy in colon cancer.
    Greene LM; Wang S; O'Boyle NM; Bright SA; Reid JE; Kelly P; Meegan MJ; Zisterer DM
    Oncol Rep; 2013 Jun; 29(6):2451-8. PubMed ID: 23564200
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
    Zhou P; Liang Y; Zhang H; Jiang H; Feng K; Xu P; Wang J; Wang X; Ding K; Luo C; Liu M; Wang Y
    Eur J Med Chem; 2018 Jan; 144():817-842. PubMed ID: 29306206
    [TBL] [Abstract][Full Text] [Related]  

  • 17. β-Lactam analogues of combretastatin A-4 prevent metabolic inactivation by glucuronidation in chemoresistant HT-29 colon cancer cells.
    Malebari AM; Greene LM; Nathwani SM; Fayne D; O'Boyle NM; Wang S; Twamley B; Zisterer DM; Meegan MJ
    Eur J Med Chem; 2017 Apr; 130():261-285. PubMed ID: 28254699
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Imidazolone-amide bridges and their effects on tubulin polymerization in cis-locked vinylogous combretastatin-A4 analogues: synthesis and biological evaluation.
    Li YW; Liu J; Liu N; Shi D; Zhou XT; Lv JG; Zhu J; Zheng CH; Zhou YJ
    Bioorg Med Chem; 2011 Jun; 19(11):3579-84. PubMed ID: 21536450
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and structure-activity relationships of constrained heterocyclic analogues of combretastatin A4.
    Arthuis M; Pontikis R; Chabot GG; Seguin J; Quentin L; Bourg S; Morin-Allory L; Florent JC
    ChemMedChem; 2011 Sep; 6(9):1693-705. PubMed ID: 21732536
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design and synthesis of cis-restricted benzimidazole and benzothiazole mimics of combretastatin A-4 as antimitotic agents with apoptosis inducing ability.
    Ashraf M; Shaik TB; Malik MS; Syed R; Mallipeddi PL; Vardhan MVPSV; Kamal A
    Bioorg Med Chem Lett; 2016 Sep; 26(18):4527-4535. PubMed ID: 27515320
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.