393 related articles for article (PubMed ID: 26850643)
1. Biochemical characterization of a multi-drug resistant HIV-1 subtype AG reverse transcriptase: antagonism of AZT discrimination and excision pathways and sensitivity to RNase H inhibitors.
Schneider A; Corona A; Spöring I; Jordan M; Buchholz B; Maccioni E; Di Santo R; Bodem J; Tramontano E; Wöhrl BM
Nucleic Acids Res; 2016 Mar; 44(5):2310-22. PubMed ID: 26850643
[TBL] [Abstract][Full Text] [Related]
2. Analysis of the Zidovudine Resistance Mutations T215Y, M41L, and L210W in HIV-1 Reverse Transcriptase.
Boyer PL; Das K; Arnold E; Hughes SH
Antimicrob Agents Chemother; 2015 Dec; 59(12):7184-96. PubMed ID: 26324274
[TBL] [Abstract][Full Text] [Related]
3. Nucleoside analog resistance caused by insertions in the fingers of human immunodeficiency virus type 1 reverse transcriptase involves ATP-mediated excision.
Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2002 Sep; 76(18):9143-51. PubMed ID: 12186898
[TBL] [Abstract][Full Text] [Related]
4. Molecular mechanism by which the K70E mutation in human immunodeficiency virus type 1 reverse transcriptase confers resistance to nucleoside reverse transcriptase inhibitors.
Sluis-Cremer N; Sheen CW; Zelina S; Torres PS; Parikh UM; Mellors JW
Antimicrob Agents Chemother; 2007 Jan; 51(1):48-53. PubMed ID: 17088490
[TBL] [Abstract][Full Text] [Related]
5. Effects of the Delta67 complex of mutations in human immunodeficiency virus type 1 reverse transcriptase on nucleoside analog excision.
Boyer PL; Imamichi T; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2004 Sep; 78(18):9987-97. PubMed ID: 15331732
[TBL] [Abstract][Full Text] [Related]
6. The K65R mutation in human immunodeficiency virus type 1 reverse transcriptase exhibits bidirectional phenotypic antagonism with thymidine analog mutations.
Parikh UM; Bacheler L; Koontz D; Mellors JW
J Virol; 2006 May; 80(10):4971-7. PubMed ID: 16641288
[TBL] [Abstract][Full Text] [Related]
7. Selection of mutations in the connection and RNase H domains of human immunodeficiency virus type 1 reverse transcriptase that increase resistance to 3'-azido-3'-dideoxythymidine.
Brehm JH; Koontz D; Meteer JD; Pathak V; Sluis-Cremer N; Mellors JW
J Virol; 2007 Aug; 81(15):7852-9. PubMed ID: 17507476
[TBL] [Abstract][Full Text] [Related]
8. Molecular mechanisms of bidirectional antagonism between K65R and thymidine analog mutations in HIV-1 reverse transcriptase.
Parikh UM; Zelina S; Sluis-Cremer N; Mellors JW
AIDS; 2007 Jul; 21(11):1405-14. PubMed ID: 17589186
[TBL] [Abstract][Full Text] [Related]
9. Thymidine analogue resistance suppression by V75I of HIV-1 reverse transcriptase: effects of substituting valine 75 on stavudine excision and discrimination.
Matamoros T; Nevot M; Martínez MA; Menéndez-Arias L
J Biol Chem; 2009 Nov; 284(47):32792-802. PubMed ID: 19801659
[TBL] [Abstract][Full Text] [Related]
10. Transmitted human immunodeficiency virus type 1 carrying the D67N or K219Q/E mutation evolves rapidly to zidovudine resistance in vitro and shows a high replicative fitness in the presence of zidovudine.
García-Lerma JG; MacInnes H; Bennett D; Weinstock H; Heneine W
J Virol; 2004 Jul; 78(14):7545-52. PubMed ID: 15220429
[TBL] [Abstract][Full Text] [Related]
11. Molecular basis of the association of H208Y and thymidine analogue resistance mutations M41L, L210W and T215Y in the HIV-1 reverse transcriptase of treated patients.
Betancor G; Nevot M; Mendieta J; Gómez-Puertas P; Martínez MA; Menéndez-Arias L
Antiviral Res; 2014 Jun; 106():42-52. PubMed ID: 24667336
[TBL] [Abstract][Full Text] [Related]
12. A rapid phenotypic assay for detecting multiple nucleoside analogue reverse transcriptase inhibitor-resistant HIV-1 in plasma.
Qari SH; Winters M; Vandamme AM; Merigan T; Heneine W
Antivir Ther; 2002 Jun; 7(2):131-9. PubMed ID: 12212925
[TBL] [Abstract][Full Text] [Related]
13. Pre-steady-state kinetic characterization of wild type and 3'-azido-3'-deoxythymidine (AZT) resistant human immunodeficiency virus type 1 reverse transcriptase: implication of RNA directed DNA polymerization in the mechanism of AZT resistance.
Kerr SG; Anderson KS
Biochemistry; 1997 Nov; 36(46):14064-70. PubMed ID: 9369478
[TBL] [Abstract][Full Text] [Related]
14. Mutational patterns associated with the 69 insertion complex in multi-drug-resistant HIV-1 reverse transcriptase that confer increased excision activity and high-level resistance to zidovudine.
Cases-González CE; Franco S; Martínez MA; Menéndez-Arias L
J Mol Biol; 2007 Jan; 365(2):298-309. PubMed ID: 17070543
[TBL] [Abstract][Full Text] [Related]
15. Correlation between viral resistance to zidovudine and resistance at the reverse transcriptase level for a panel of human immunodeficiency virus type 1 mutants.
Lennerstrand J; Hertogs K; Stammers DK; Larder BA
J Virol; 2001 Aug; 75(15):7202-5. PubMed ID: 11435603
[TBL] [Abstract][Full Text] [Related]
16. Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase.
Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2001 May; 75(10):4832-42. PubMed ID: 11312355
[TBL] [Abstract][Full Text] [Related]
17. N348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance.
Yap SH; Sheen CW; Fahey J; Zanin M; Tyssen D; Lima VD; Wynhoven B; Kuiper M; Sluis-Cremer N; Harrigan PR; Tachedjian G
PLoS Med; 2007 Dec; 4(12):e335. PubMed ID: 18052601
[TBL] [Abstract][Full Text] [Related]
18. Enzymatic characterization of human immunodeficiency virus type 1 reverse transcriptase resistant to multiple 2',3'-dideoxynucleoside 5'-triphosphates.
Ueno T; Shirasaka T; Mitsuya H
J Biol Chem; 1995 Oct; 270(40):23605-11. PubMed ID: 7559526
[TBL] [Abstract][Full Text] [Related]
19. Non-nucleoside inhibitors of HIV-1 reverse transcriptase inhibit phosphorolysis and resensitize the 3'-azido-3'-deoxythymidine (AZT)-resistant polymerase to AZT-5'-triphosphate.
Odriozola L; Cruchaga C; Andréola M; Dollé V; Nguyen CH; Tarrago-Litvak L; Pérez-Mediavilla A; Martínez-Irujo JJ
J Biol Chem; 2003 Oct; 278(43):42710-6. PubMed ID: 12917424
[TBL] [Abstract][Full Text] [Related]
20. The M184V mutation reduces the selective excision of zidovudine 5'-monophosphate (AZTMP) by the reverse transcriptase of human immunodeficiency virus type 1.
Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2002 Apr; 76(7):3248-56. PubMed ID: 11884549
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]