BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

376 related articles for article (PubMed ID: 26854665)

  • 1. Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.
    Yuan Z; Bai L; Sun J; Georgescu R; Liu J; O'Donnell ME; Li H
    Nat Struct Mol Biol; 2016 Mar; 23(3):217-24. PubMed ID: 26854665
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cryo-EM structures of the eukaryotic replicative helicase bound to a translocation substrate.
    Abid Ali F; Renault L; Gannon J; Gahlon HL; Kotecha A; Zhou JC; Rueda D; Costa A
    Nat Commun; 2016 Feb; 7():10708. PubMed ID: 26888060
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome.
    Eickhoff P; Kose HB; Martino F; Petojevic T; Abid Ali F; Locke J; Tamberg N; Nans A; Berger JM; Botchan MR; Yardimci H; Costa A
    Cell Rep; 2019 Sep; 28(10):2673-2688.e8. PubMed ID: 31484077
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation.
    Georgescu R; Yuan Z; Bai L; de Luna Almeida Santos R; Sun J; Zhang D; Yurieva O; Li H; O'Donnell ME
    Proc Natl Acad Sci U S A; 2017 Jan; 114(5):E697-E706. PubMed ID: 28096349
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mcm10 plays a role in functioning of the eukaryotic replicative DNA helicase, Cdc45-Mcm-GINS.
    Watase G; Takisawa H; Kanemaki MT
    Curr Biol; 2012 Feb; 22(4):343-9. PubMed ID: 22285032
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CryoEM structures of human CMG-ATPγS-DNA and CMG-AND-1 complexes.
    Rzechorzek NJ; Hardwick SW; Jatikusumo VA; Chirgadze DY; Pellegrini L
    Nucleic Acids Res; 2020 Jul; 48(12):6980-6995. PubMed ID: 32453425
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The mechanism of eukaryotic CMG helicase activation.
    Douglas ME; Ali FA; Costa A; Diffley JFX
    Nature; 2018 Mar; 555(7695):265-268. PubMed ID: 29489749
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The eukaryotic CMG helicase pumpjack and integration into the replisome.
    Sun J; Yuan Z; Georgescu R; Li H; O'Donnell M
    Nucleus; 2016 Apr; 7(2):146-54. PubMed ID: 27310307
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Action of CMG with strand-specific DNA blocks supports an internal unwinding mode for the eukaryotic replicative helicase.
    Langston L; O'Donnell M
    Elife; 2017 Mar; 6():. PubMed ID: 28346143
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DNA unwinding mechanism of a eukaryotic replicative CMG helicase.
    Yuan Z; Georgescu R; Bai L; Zhang D; Li H; O'Donnell ME
    Nat Commun; 2020 Feb; 11(1):688. PubMed ID: 32019936
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mcm10 regulates DNA replication elongation by stimulating the CMG replicative helicase.
    Lõoke M; Maloney MF; Bell SP
    Genes Dev; 2017 Feb; 31(3):291-305. PubMed ID: 28270517
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The mechanism of DNA unwinding by the eukaryotic replicative helicase.
    Burnham DR; Kose HB; Hoyle RB; Yardimci H
    Nat Commun; 2019 May; 10(1):2159. PubMed ID: 31089141
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The structural mechanism of dimeric DONSON in replicative helicase activation.
    Cvetkovic MA; Passaretti P; Butryn A; Reynolds-Winczura A; Kingsley G; Skagia A; Fernandez-Cuesta C; Poovathumkadavil D; George R; Chauhan AS; Jhujh SS; Stewart GS; Gambus A; Costa A
    Mol Cell; 2023 Nov; 83(22):4017-4031.e9. PubMed ID: 37820732
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
    Yuan Z; Schneider S; Dodd T; Riera A; Bai L; Yan C; Magdalou I; Ivanov I; Stillman B; Li H; Speck C
    Proc Natl Acad Sci U S A; 2020 Jul; 117(30):17747-17756. PubMed ID: 32669428
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Eukaryotic CMG Helicase at the Replication Fork: Emerging Architecture Reveals an Unexpected Mechanism.
    Li H; O'Donnell ME
    Bioessays; 2018 Mar; 40(3):. PubMed ID: 29405332
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome.
    Simon AC; Zhou JC; Perera RL; van Deursen F; Evrin C; Ivanova ME; Kilkenny ML; Renault L; Kjaer S; Matak-Vinković D; Labib K; Costa A; Pellegrini L
    Nature; 2014 Jun; 510(7504):293-297. PubMed ID: 24805245
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Archaeal MCM Proteins as an Analog for the Eukaryotic Mcm2-7 Helicase to Reveal Essential Features of Structure and Function.
    Miller JM; Enemark EJ
    Archaea; 2015; 2015():305497. PubMed ID: 26539061
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The structural basis for MCM2-7 helicase activation by GINS and Cdc45.
    Costa A; Ilves I; Tamberg N; Petojevic T; Nogales E; Botchan MR; Berger JM
    Nat Struct Mol Biol; 2011 Apr; 18(4):471-7. PubMed ID: 21378962
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanism of replication origin melting nucleated by CMG helicase assembly.
    Lewis JS; Gross MH; Sousa J; Henrikus SS; Greiwe JF; Nans A; Diffley JFX; Costa A
    Nature; 2022 Jun; 606(7916):1007-1014. PubMed ID: 35705812
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cdc45 (cell division cycle protein 45) guards the gate of the Eukaryote Replisome helicase stabilizing leading strand engagement.
    Petojevic T; Pesavento JJ; Costa A; Liang J; Wang Z; Berger JM; Botchan MR
    Proc Natl Acad Sci U S A; 2015 Jan; 112(3):E249-58. PubMed ID: 25561522
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.