These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

464 related articles for article (PubMed ID: 26855179)

  • 1. Acetylation of lysine 109 modulates pregnane X receptor DNA binding and transcriptional activity.
    Pasquel D; Doricakova A; Li H; Kortagere S; Krasowski MD; Biswas A; Walton WG; Redinbo MR; Dvorak Z; Mani S
    Biochim Biophys Acta; 2016 Sep; 1859(9):1155-1169. PubMed ID: 26855179
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A SUMO-acetyl switch in PXR biology.
    Cui W; Sun M; Zhang S; Shen X; Galeva N; Williams TD; Staudinger JL
    Biochim Biophys Acta; 2016 Sep; 1859(9):1170-1182. PubMed ID: 26883953
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A comprehensive analysis and functional characterization of naturally occurring non-synonymous variants of nuclear receptor PXR.
    Rana M; Devi S; Gourinath S; Goswami R; Tyagi RK
    Biochim Biophys Acta; 2016 Sep; 1859(9):1183-1197. PubMed ID: 26962022
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of pregnane X receptor (PXR) function and UGT1A1 gene expression by posttranslational modification of PXR protein.
    Sugatani J; Uchida T; Kurosawa M; Yamaguchi M; Yamazaki Y; Ikari A; Miwa M
    Drug Metab Dispos; 2012 Oct; 40(10):2031-40. PubMed ID: 22829544
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MicroRNA-30c-1-3p is a silencer of the pregnane X receptor by targeting the 3'-untranslated region and alters the expression of its target gene cytochrome P450 3A4.
    Vachirayonstien T; Yan B
    Biochim Biophys Acta; 2016 Sep; 1859(9):1238-1244. PubMed ID: 27085140
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Acetylation of pregnane X receptor protein determines selective function independent of ligand activation.
    Biswas A; Pasquel D; Tyagi RK; Mani S
    Biochem Biophys Res Commun; 2011 Mar; 406(3):371-6. PubMed ID: 21329659
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The role of residues T248, Y249 and T422 in the function of human pregnane X receptor.
    Doricakova A; Novotna A; Vrzal R; Pavek P; Dvorak Z
    Arch Toxicol; 2013 Feb; 87(2):291-301. PubMed ID: 22976785
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure and function of the human nuclear xenobiotic receptor PXR.
    Carnahan VE; Redinbo MR
    Curr Drug Metab; 2005 Aug; 6(4):357-67. PubMed ID: 16101574
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel functions of PXR in cardiometabolic disease.
    Zhou C
    Biochim Biophys Acta; 2016 Sep; 1859(9):1112-1120. PubMed ID: 26924429
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Crystal structure of the pregnane X receptor-estradiol complex provides insights into endobiotic recognition.
    Xue Y; Moore LB; Orans J; Peng L; Bencharit S; Kliewer SA; Redinbo MR
    Mol Endocrinol; 2007 May; 21(5):1028-38. PubMed ID: 17327420
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential regulation of CYP3A4 promoter activity by a new class of natural product derivatives binding to pregnane X receptor.
    Banerjee M; Chen T
    Biochem Pharmacol; 2013 Sep; 86(6):824-35. PubMed ID: 23928187
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural and functional analysis of the human nuclear xenobiotic receptor PXR in complex with RXRα.
    Wallace BD; Betts L; Talmage G; Pollet RM; Holman NS; Redinbo MR
    J Mol Biol; 2013 Jul; 425(14):2561-77. PubMed ID: 23602807
    [TBL] [Abstract][Full Text] [Related]  

  • 13. FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states.
    Kemper JK; Xiao Z; Ponugoti B; Miao J; Fang S; Kanamaluru D; Tsang S; Wu SY; Chiang CM; Veenstra TD
    Cell Metab; 2009 Nov; 10(5):392-404. PubMed ID: 19883617
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human PXR forms a tryptophan zipper-mediated homodimer.
    Noble SM; Carnahan VE; Moore LB; Luntz T; Wang H; Ittoop OR; Stimmel JB; Davis-Searles PR; Watkins RE; Wisely GB; LeCluyse E; Tripathy A; McDonnell DP; Redinbo MR
    Biochemistry; 2006 Jul; 45(28):8579-89. PubMed ID: 16834332
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of PXR in drug metabolism: chemical and structural perspectives.
    Gee RRF; Huber AD; Chen T
    Expert Opin Drug Metab Toxicol; 2024; 20(1-2):9-23. PubMed ID: 38251638
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Polycyclic aromatic hydrocarbons stimulate human CYP3A4 promoter activity via PXR.
    Luckert C; Ehlers A; Buhrke T; Seidel A; Lampen A; Hessel S
    Toxicol Lett; 2013 Oct; 222(2):180-8. PubMed ID: 23845848
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification and interplay of sequence specific DNA binding proteins involved in regulation of human Pregnane and Xenobiotic Receptor gene.
    Saradhi M; Kumari S; Rana M; Mukhopadhyay G; Tyagi RK
    Exp Cell Res; 2015 Dec; 339(2):187-96. PubMed ID: 26586566
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bazedoxifene-scaffold-based mimetics of solomonsterols A and B as novel pregnane X receptor antagonists.
    Hodnik Ž; Peterlin Mašič L; Tomašić T; Smodiš D; D'Amore C; Fiorucci S; Kikelj D
    J Med Chem; 2014 Jun; 57(11):4819-33. PubMed ID: 24828006
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel yeast-based strategy unveils antagonist binding regions on the nuclear xenobiotic receptor PXR.
    Li H; Redinbo MR; Venkatesh M; Ekins S; Chaudhry A; Bloch N; Negassa A; Mukherjee P; Kalpana G; Mani S
    J Biol Chem; 2013 May; 288(19):13655-68. PubMed ID: 23525103
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PXR- and CAR-mediated herbal effect on human diseases.
    Xu C; Huang M; Bi H
    Biochim Biophys Acta; 2016 Sep; 1859(9):1121-1129. PubMed ID: 26906544
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.