BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

336 related articles for article (PubMed ID: 26858253)

  • 1. Cytokines Regulate β-Cell Thioredoxin-interacting Protein (TXNIP) via Distinct Mechanisms and Pathways.
    Hong K; Xu G; Grayson TB; Shalev A
    J Biol Chem; 2016 Apr; 291(16):8428-39. PubMed ID: 26858253
    [TBL] [Abstract][Full Text] [Related]  

  • 2. High beta-cell mass prevents streptozotocin-induced diabetes in thioredoxin-interacting protein-deficient mice.
    Masson E; Koren S; Razik F; Goldberg H; Kwan EP; Sheu L; Gaisano HY; Fantus IG
    Am J Physiol Endocrinol Metab; 2009 Jun; 296(6):E1251-61. PubMed ID: 19223654
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Thioredoxin-interacting protein regulates insulin transcription through microRNA-204.
    Xu G; Chen J; Jing G; Shalev A
    Nat Med; 2013 Sep; 19(9):1141-6. PubMed ID: 23975026
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MicroRNA-200 is induced by thioredoxin-interacting protein and regulates Zeb1 protein signaling and beta cell apoptosis.
    Filios SR; Xu G; Chen J; Hong K; Jing G; Shalev A
    J Biol Chem; 2014 Dec; 289(52):36275-83. PubMed ID: 25391656
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Thioredoxin-interacting protein promotes islet amyloid polypeptide expression through miR-124a and FoxA2.
    Jing G; Westwell-Roper C; Chen J; Xu G; Verchere CB; Shalev A
    J Biol Chem; 2014 Apr; 289(17):11807-11815. PubMed ID: 24627476
    [TBL] [Abstract][Full Text] [Related]  

  • 6. W2476 ameliorates β-cell dysfunction and exerts therapeutic effects in mouse models of diabetes via modulation of the thioredoxin-interacting protein signaling pathway.
    Li T; Lin GY; Zhong L; Zhou Y; Wang J; Zhu Y; Feng Y; Cai XQ; Liu Q; Nosjean O; Boutin JA; Renard P; Yang DH; Wang MW
    Acta Pharmacol Sin; 2017 Jul; 38(7):1024-1037. PubMed ID: 28502980
    [TBL] [Abstract][Full Text] [Related]  

  • 7. FOXO1 competes with carbohydrate response element-binding protein (ChREBP) and inhibits thioredoxin-interacting protein (TXNIP) transcription in pancreatic beta cells.
    Kibbe C; Chen J; Xu G; Jing G; Shalev A
    J Biol Chem; 2013 Aug; 288(32):23194-202. PubMed ID: 23803610
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glucose-stimulated expression of Txnip is mediated by carbohydrate response element-binding protein, p300, and histone H4 acetylation in pancreatic beta cells.
    Cha-Molstad H; Saxena G; Chen J; Shalev A
    J Biol Chem; 2009 Jun; 284(25):16898-16905. PubMed ID: 19411249
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lack of TXNIP protects against mitochondria-mediated apoptosis but not against fatty acid-induced ER stress-mediated beta-cell death.
    Chen J; Fontes G; Saxena G; Poitout V; Shalev A
    Diabetes; 2010 Feb; 59(2):440-7. PubMed ID: 19875615
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes.
    Chen J; Hui ST; Couto FM; Mungrue IN; Davis DB; Attie AD; Lusis AJ; Davis RA; Shalev A
    FASEB J; 2008 Oct; 22(10):3581-94. PubMed ID: 18552236
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Thioredoxin-interacting protein gene expression via MondoA is rapidly and transiently suppressed during inflammatory responses.
    Kanari Y; Sato Y; Aoyama S; Muta T
    PLoS One; 2013; 8(3):e59026. PubMed ID: 23520550
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Deletion of thioredoxin-interacting protein improves cardiac inotropic reserve in the streptozotocin-induced diabetic heart.
    Myers RB; Fomovsky GM; Lee S; Tan M; Wang BF; Patwari P; Yoshioka J
    Am J Physiol Heart Circ Physiol; 2016 Jun; 310(11):H1748-59. PubMed ID: 27037370
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Thioredoxin-interacting protein: a critical link between glucose toxicity and beta-cell apoptosis.
    Chen J; Saxena G; Mungrue IN; Lusis AJ; Shalev A
    Diabetes; 2008 Apr; 57(4):938-44. PubMed ID: 18171713
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Redox regulation by nuclear factor erythroid 2-related factor 2: gatekeeping for the basal and diabetes-induced expression of thioredoxin-interacting protein.
    He X; Ma Q
    Mol Pharmacol; 2012 Nov; 82(5):887-97. PubMed ID: 22869588
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Endoplasmic reticulum stress-induced IRE1α activation mediates cross-talk of GSK-3β and XBP-1 to regulate inflammatory cytokine production.
    Kim S; Joe Y; Kim HJ; Kim YS; Jeong SO; Pae HO; Ryter SW; Surh YJ; Chung HT
    J Immunol; 2015 May; 194(9):4498-506. PubMed ID: 25821218
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms.
    Brozzi F; Nardelli TR; Lopes M; Millard I; Barthson J; Igoillo-Esteve M; Grieco FA; Villate O; Oliveira JM; Casimir M; Bugliani M; Engin F; Hotamisligil GS; Marchetti P; Eizirik DL
    Diabetologia; 2015 Oct; 58(10):2307-16. PubMed ID: 26099855
    [TBL] [Abstract][Full Text] [Related]  

  • 17. AMP-activated protein kinase (AMPK) mediates nutrient regulation of thioredoxin-interacting protein (TXNIP) in pancreatic beta-cells.
    Shaked M; Ketzinel-Gilad M; Cerasi E; Kaiser N; Leibowitz G
    PLoS One; 2011; 6(12):e28804. PubMed ID: 22194917
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Thioredoxin-Interacting Protein Deficiency Protects against Diabetic Nephropathy.
    Shah A; Xia L; Masson EA; Gui C; Momen A; Shikatani EA; Husain M; Quaggin S; John R; Fantus IG
    J Am Soc Nephrol; 2015 Dec; 26(12):2963-77. PubMed ID: 25855771
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasome.
    Oslowski CM; Hara T; O'Sullivan-Murphy B; Kanekura K; Lu S; Hara M; Ishigaki S; Zhu LJ; Hayashi E; Hui ST; Greiner D; Kaufman RJ; Bortell R; Urano F
    Cell Metab; 2012 Aug; 16(2):265-73. PubMed ID: 22883234
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Thioredoxin-interacting protein is stimulated by glucose through a carbohydrate response element and induces beta-cell apoptosis.
    Minn AH; Hafele C; Shalev A
    Endocrinology; 2005 May; 146(5):2397-405. PubMed ID: 15705778
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.