BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

370 related articles for article (PubMed ID: 26861754)

  • 1. Induction of WNT11 by hypoxia and hypoxia-inducible factor-1α regulates cell proliferation, migration and invasion.
    Mori H; Yao Y; Learman BS; Kurozumi K; Ishida J; Ramakrishnan SK; Overmyer KA; Xue X; Cawthorn WP; Reid MA; Taylor M; Ning X; Shah YM; MacDougald OA
    Sci Rep; 2016 Feb; 6():21520. PubMed ID: 26861754
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
    Carroll VA; Ashcroft M
    Cancer Res; 2006 Jun; 66(12):6264-70. PubMed ID: 16778202
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1alpha protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and enhanced tumor angiogenesis.
    Welsh SJ; Bellamy WT; Briehl MM; Powis G
    Cancer Res; 2002 Sep; 62(17):5089-95. PubMed ID: 12208766
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Silencing hypoxia-inducible factor-1alpha inhibits cell migration and invasion under hypoxic environment in malignant gliomas.
    Fujiwara S; Nakagawa K; Harada H; Nagato S; Furukawa K; Teraoka M; Seno T; Oka K; Iwata S; Ohnishi T
    Int J Oncol; 2007 Apr; 30(4):793-802. PubMed ID: 17332917
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of hypoxia-inducible factor 1alpha in gastric cancer cell growth, angiogenesis, and vessel maturation.
    Stoeltzing O; McCarty MF; Wey JS; Fan F; Liu W; Belcheva A; Bucana CD; Semenza GL; Ellis LM
    J Natl Cancer Inst; 2004 Jun; 96(12):946-56. PubMed ID: 15199114
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reduction of hypoxia-induced transcription through the repression of hypoxia-inducible factor-1alpha/aryl hydrocarbon receptor nuclear translocator DNA binding by the 90-kDa heat-shock protein inhibitor radicicol.
    Hur E; Kim HH; Choi SM; Kim JH; Yim S; Kwon HJ; Choi Y; Kim DK; Lee MO; Park H
    Mol Pharmacol; 2002 Nov; 62(5):975-82. PubMed ID: 12391259
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
    Blancher C; Moore JW; Robertson N; Harris AL
    Cancer Res; 2001 Oct; 61(19):7349-55. PubMed ID: 11585776
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
    Krieg M; Haas R; Brauch H; Acker T; Flamme I; Plate KH
    Oncogene; 2000 Nov; 19(48):5435-43. PubMed ID: 11114720
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Expression of hypoxia-inducible factor 1alpha, hypoxia-inducible factor 2alpha, and von Hippel-Lindau protein in epithelial ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1alpha is an independent prognostic factor in ovarian carcinoma.
    Osada R; Horiuchi A; Kikuchi N; Yoshida J; Hayashi A; Ota M; Katsuyama Y; Melillo G; Konishi I
    Hum Pathol; 2007 Sep; 38(9):1310-20. PubMed ID: 17555795
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice.
    Rankin EB; Higgins DF; Walisser JA; Johnson RS; Bradfield CA; Haase VH
    Mol Cell Biol; 2005 Apr; 25(8):3163-72. PubMed ID: 15798202
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Topotecan blocks hypoxia-inducible factor-1alpha and vascular endothelial growth factor expression induced by insulin-like growth factor-I in neuroblastoma cells.
    Beppu K; Nakamura K; Linehan WM; Rapisarda A; Thiele CJ
    Cancer Res; 2005 Jun; 65(11):4775-81. PubMed ID: 15930297
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Knock down of HIF-1alpha in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres.
    Méndez O; Zavadil J; Esencay M; Lukyanov Y; Santovasi D; Wang SC; Newcomb EW; Zagzag D
    Mol Cancer; 2010 Jun; 9():133. PubMed ID: 20515450
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rhapontigenin inhibited hypoxia inducible factor 1 alpha accumulation and angiogenesis in hypoxic PC-3 prostate cancer cells.
    Jung DB; Lee HJ; Jeong SJ; Lee HJ; Lee EO; Kim YC; Ahn KS; Chen CY; Kim SH
    Biol Pharm Bull; 2011; 34(6):850-5. PubMed ID: 21628883
    [TBL] [Abstract][Full Text] [Related]  

  • 14. RNAi Knockdown of Hypoxia-Inducible Factor-1α Decreased the Proliferation, Migration, and Invasion of Hypoxic Hepatocellular Carcinoma Cells.
    Chen C; Liu R; Wang J; Yan Z; Qian S; Zhang W
    Cell Biochem Biophys; 2015 Apr; 71(3):1677-84. PubMed ID: 25388848
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Long noncoding RNA HOTAIR, a hypoxia-inducible factor-1α activated driver of malignancy, enhances hypoxic cancer cell proliferation, migration, and invasion in non-small cell lung cancer.
    Zhou C; Ye L; Jiang C; Bai J; Chi Y; Zhang H
    Tumour Biol; 2015 Dec; 36(12):9179-88. PubMed ID: 26088446
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Minocycline accelerates hypoxia-inducible factor-1 alpha degradation and inhibits hypoxia-induced neovasculogenesis through prolyl hydroxylase, von Hippel-Lindau-dependent pathway.
    Li CH; Liao PL; Yang YT; Huang SH; Lin CH; Cheng YW; Kang JJ
    Arch Toxicol; 2014 Mar; 88(3):659-71. PubMed ID: 24292262
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Vernolide-A inhibits radiation-induced hypoxia-mediated tumor angiogenesis by regulating HIF-1α, MMP-2, MMP-9, and VEGF.
    Pratheeshkumar P; Kuttan G
    J Environ Pathol Toxicol Oncol; 2011; 30(2):139-51. PubMed ID: 21967458
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Wogonin inhibits tumor angiogenesis via degradation of HIF-1α protein.
    Song X; Yao J; Wang F; Zhou M; Zhou Y; Wang H; Wei L; Zhao L; Li Z; Lu N; Guo Q
    Toxicol Appl Pharmacol; 2013 Sep; 271(2):144-55. PubMed ID: 23707765
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A hypoxia-independent hypoxia-inducible factor-1 activation pathway induced by phosphatidylinositol-3 kinase/Akt in HER2 overexpressing cells.
    Li YM; Zhou BP; Deng J; Pan Y; Hay N; Hung MC
    Cancer Res; 2005 Apr; 65(8):3257-63. PubMed ID: 15833858
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A HIF-1α-driven feed-forward loop augments HIF signalling in Hep3B cells by upregulation of ARNT.
    Mandl M; Lieberum MK; Depping R
    Cell Death Dis; 2016 Jun; 7(6):e2284. PubMed ID: 27362802
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.