BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 26864725)

  • 1. Targeting NOTCH1 in T-ALL: Starving the dragon.
    Herranz D; Ferrando AA
    Cell Cycle; 2016; 15(4):483-4. PubMed ID: 26864725
    [No Abstract]   [Full Text] [Related]  

  • 2. T-ALL: ALL a matter of Translation?
    Girardi T; De Keersmaecker K
    Haematologica; 2015 Mar; 100(3):293-5. PubMed ID: 25740104
    [No Abstract]   [Full Text] [Related]  

  • 3. The relevance of PTEN-AKT in relation to NOTCH1-directed treatment strategies in T-cell acute lymphoblastic leukemia.
    Mendes RD; Canté-Barrett K; Pieters R; Meijerink JP
    Haematologica; 2016 Sep; 101(9):1010-7. PubMed ID: 27582570
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group.
    Larson Gedman A; Chen Q; Kugel Desmoulin S; Ge Y; LaFiura K; Haska CL; Cherian C; Devidas M; Linda SB; Taub JW; Matherly LH
    Leukemia; 2009 Aug; 23(8):1417-25. PubMed ID: 19340001
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of PTEN by CK2 and Notch1 in primary T-cell acute lymphoblastic leukemia: rationale for combined use of CK2- and gamma-secretase inhibitors.
    Silva A; Jotta PY; Silveira AB; Ribeiro D; Brandalise SR; Yunes JA; Barata JT
    Haematologica; 2010 Apr; 95(4):674-8. PubMed ID: 20015880
    [TBL] [Abstract][Full Text] [Related]  

  • 6. NOTCH1 activation clinically antagonizes the unfavorable effect of PTEN inactivation in BFM-treated children with precursor T-cell acute lymphoblastic leukemia.
    Bandapalli OR; Zimmermann M; Kox C; Stanulla M; Schrappe M; Ludwig WD; Koehler R; Muckenthaler MU; Kulozik AE
    Haematologica; 2013 Jun; 98(6):928-36. PubMed ID: 23349303
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia.
    Palomero T; Sulis ML; Cortina M; Real PJ; Barnes K; Ciofani M; Caparros E; Buteau J; Brown K; Perkins SL; Bhagat G; Agarwal AM; Basso G; Castillo M; Nagase S; Cordon-Cardo C; Parsons R; Zúñiga-Pflücker JC; Dominguez M; Ferrando AA
    Nat Med; 2007 Oct; 13(10):1203-10. PubMed ID: 17873882
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Genetics and Mechanisms of T-Cell Acute Lymphoblastic Leukemia.
    Gianni F; Belver L; Ferrando A
    Cold Spring Harb Perspect Med; 2020 Mar; 10(3):. PubMed ID: 31570389
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Recent advances on NOTCH signaling in T-ALL.
    Tzoneva G; Ferrando AA
    Curr Top Microbiol Immunol; 2012; 360():163-82. PubMed ID: 22673746
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Murine Pten(-/-) T-ALL requires non-redundant PI3K/mTOR and DLL4/Notch1 signals for maintenance and γc/TCR signals for thymic exit.
    Hagenbeek TJ; Wu X; Choy L; Sanchez-Irizarry C; Seshagiri S; Stinson J; Siebel CW; Spits H
    Cancer Lett; 2014 May; 346(2):237-48. PubMed ID: 24384093
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Posttranscriptional deregulation of MYC via PTEN constitutes a major alternative pathway of MYC activation in T-cell acute lymphoblastic leukemia.
    Bonnet M; Loosveld M; Montpellier B; Navarro JM; Quilichini B; Picard C; Di Cristofaro J; Bagnis C; Fossat C; Hernandez L; Mamessier E; Roulland S; Morgado E; Formisano-Tréziny C; Dik WA; Langerak AW; Prebet T; Vey N; Michel G; Gabert J; Soulier J; Macintyre EA; Asnafi V; Payet-Bornet D; Nadel B
    Blood; 2011 Jun; 117(24):6650-9. PubMed ID: 21527520
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss.
    Medyouf H; Gao X; Armstrong F; Gusscott S; Liu Q; Gedman AL; Matherly LH; Schultz KR; Pflumio F; You MJ; Weng AP
    Blood; 2010 Feb; 115(6):1175-84. PubMed ID: 20008304
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Therapeutic antibody targeting of Notch1 in T-acute lymphoblastic leukemia xenografts.
    Agnusdei V; Minuzzo S; Frasson C; Grassi A; Axelrod F; Satyal S; Gurney A; Hoey T; Seganfreddo E; Basso G; Valtorta S; Moresco RM; Amadori A; Indraccolo S
    Leukemia; 2014 Feb; 28(2):278-88. PubMed ID: 23774673
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia.
    Zuurbier L; Petricoin EF; Vuerhard MJ; Calvert V; Kooi C; Buijs-Gladdines JG; Smits WK; Sonneveld E; Veerman AJ; Kamps WA; Horstmann M; Pieters R; Meijerink JP
    Haematologica; 2012 Sep; 97(9):1405-13. PubMed ID: 22491738
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Focused chemical genomics using zebrafish xenotransplantation as a pre-clinical therapeutic platform for T-cell acute lymphoblastic leukemia.
    Bentley VL; Veinotte CJ; Corkery DP; Pinder JB; LeBlanc MA; Bedard K; Weng AP; Berman JN; Dellaire G
    Haematologica; 2015 Jan; 100(1):70-6. PubMed ID: 25281505
    [TBL] [Abstract][Full Text] [Related]  

  • 16. T-cell acute lymphoblastic leukemias express a unique truncated FAT1 isoform that cooperates with NOTCH1 in leukemia development.
    de Bock CE; Down M; Baidya K; Sweron B; Boyd AW; Fiers M; Burns GF; Molloy TJ; Lock RB; Soulier J; Taghon T; Van Vlierberghe P; Cools J; Holst J; Thorne RF
    Haematologica; 2019 May; 104(5):e204-e207. PubMed ID: 30514801
    [No Abstract]   [Full Text] [Related]  

  • 17. Molecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia.
    Paganin M; Ferrando A
    Blood Rev; 2011 Mar; 25(2):83-90. PubMed ID: 20965628
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PI3Kγ/δ and NOTCH1 Cross-Regulate Pathways That Define the T-cell Acute Lymphoblastic Leukemia Disease Signature.
    Efimenko E; Davé UP; Lebedeva IV; Shen Y; Sanchez-Quintero MJ; Diolaiti D; Kung A; Lannutti BJ; Chen J; Realubit R; Niatsetskaya Z; Ten V; Karan C; Chen X; Califano A; Diacovo TG
    Mol Cancer Ther; 2017 Oct; 16(10):2069-2082. PubMed ID: 28716817
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Toward a NOTCH1/FBXW7/RAS/PTEN-based oncogenetic risk classification of adult T-cell acute lymphoblastic leukemia: a Group for Research in Adult Acute Lymphoblastic Leukemia study.
    Trinquand A; Tanguy-Schmidt A; Ben Abdelali R; Lambert J; Beldjord K; Lengliné E; De Gunzburg N; Payet-Bornet D; Lhermitte L; Mossafa H; Lhéritier V; Bond J; Huguet F; Buzyn A; Leguay T; Cahn JY; Thomas X; Chalandon Y; Delannoy A; Bonmati C; Maury S; Nadel B; Macintyre E; Ifrah N; Dombret H; Asnafi V
    J Clin Oncol; 2013 Dec; 31(34):4333-42. PubMed ID: 24166518
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cancer therapy resistance: chasing epigenetics.
    Nat Med; 2014 Apr; 20(4):340-1. PubMed ID: 24710376
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 7.