BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 26875934)

  • 1. Synthesis and pharmacological evaluation of nucleoside prodrugs designed to target siderophore biosynthesis in Mycobacterium tuberculosis.
    Dawadi S; Kawamura S; Rubenstein A; Remmel R; Aldrich CC
    Bioorg Med Chem; 2016 Mar; 24(6):1314-21. PubMed ID: 26875934
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and Pharmacokinetic Evaluation of Siderophore Biosynthesis Inhibitors for Mycobacterium tuberculosis.
    Nelson KM; Viswanathan K; Dawadi S; Duckworth BP; Boshoff HI; Barry CE; Aldrich CC
    J Med Chem; 2015 Jul; 58(14):5459-75. PubMed ID: 26110337
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bifunctional peptidomimetic prodrugs of didanosine for improved intestinal permeability and enhanced acidic stability: synthesis, transepithelial transport, chemical stability and pharmacokinetics.
    Yan Z; Sun J; Chang Y; Liu Y; Fu Q; Xu Y; Sun Y; Pu X; Zhang Y; Jing Y; Yin S; Zhu M; Wang Y; He Z
    Mol Pharm; 2011 Apr; 8(2):319-29. PubMed ID: 21280612
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Rationally designed nucleoside antibiotics that inhibit siderophore biosynthesis of Mycobacterium tuberculosis.
    Somu RV; Boshoff H; Qiao C; Bennett EM; Barry CE; Aldrich CC
    J Med Chem; 2006 Jan; 49(1):31-4. PubMed ID: 16392788
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of chromone, quinolone, and benzoxazinone sulfonamide nucleosides as conformationally constrained inhibitors of adenylating enzymes required for siderophore biosynthesis.
    Engelhart CA; Aldrich CC
    J Org Chem; 2013 Aug; 78(15):7470-81. PubMed ID: 23805993
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Increasing oral absorption of polar neuraminidase inhibitors: a prodrug transporter approach applied to oseltamivir analogue.
    Gupta D; Varghese Gupta S; Dahan A; Tsume Y; Hilfinger J; Lee KD; Amidon GL
    Mol Pharm; 2013 Feb; 10(2):512-22. PubMed ID: 23244438
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Investigation and conformational analysis of fluorinated nucleoside antibiotics targeting siderophore biosynthesis.
    Dawadi S; Viswanathan K; Boshoff HI; Barry CE; Aldrich CC
    J Org Chem; 2015 May; 80(10):4835-50. PubMed ID: 25916415
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 2-Aryl-8-aza-3-deazaadenosine analogues of 5'-O-[N-(salicyl)sulfamoyl]adenosine: Nucleoside antibiotics that block siderophore biosynthesis in Mycobacterium tuberculosis.
    Krajczyk A; Zeidler J; Januszczyk P; Dawadi S; Boshoff HI; Barry CE; Ostrowski T; Aldrich CC
    Bioorg Med Chem; 2016 Jul; 24(14):3133-43. PubMed ID: 27265685
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of siderophore biosynthesis in Mycobacterium tuberculosis with nucleoside bisubstrate analogues: structure-activity relationships of the nucleobase domain of 5'-O-[N-(salicyl)sulfamoyl]adenosine.
    Neres J; Labello NP; Somu RV; Boshoff HI; Wilson DJ; Vannada J; Chen L; Barry CE; Bennett EM; Aldrich CC
    J Med Chem; 2008 Sep; 51(17):5349-70. PubMed ID: 18690677
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dipeptidyl peptidase IV dependent water-soluble prodrugs of highly lipophilic bicyclic nucleoside analogues.
    Diez-Torrubia A; Balzarini J; Andrei G; Snoeck R; De Meester I; Camarasa MJ; Velázquez S
    J Med Chem; 2011 Mar; 54(6):1927-42. PubMed ID: 21332170
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nucleoside diphosphate and triphosphate prodrugs - An unsolvable task?
    Meier C
    Antivir Chem Chemother; 2017 Dec; 25(3):69-82. PubMed ID: 29096525
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, transport and pharmacokinetics of 5'-amino acid ester prodrugs of 1-beta-D-arabinofuranosylcytosine.
    Sun Y; Sun J; Shi S; Jing Y; Yin S; Chen Y; Li G; Xu Y; He Z
    Mol Pharm; 2009; 6(1):315-25. PubMed ID: 19115956
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enhancing the intestinal membrane permeability of zanamivir: a carrier mediated prodrug approach.
    Gupta SV; Gupta D; Sun J; Dahan A; Tsume Y; Hilfinger J; Lee KD; Amidon GL
    Mol Pharm; 2011 Dec; 8(6):2358-67. PubMed ID: 21905667
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nucleoside ester prodrug substrate specificity of liver carboxylesterase.
    Landowski CP; Lorenzi PL; Song X; Amidon GL
    J Pharmacol Exp Ther; 2006 Feb; 316(2):572-80. PubMed ID: 16223870
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antitubercular nucleosides that inhibit siderophore biosynthesis: SAR of the glycosyl domain.
    Somu RV; Wilson DJ; Bennett EM; Boshoff HI; Celia L; Beck BJ; Barry CE; Aldrich CC
    J Med Chem; 2006 Dec; 49(26):7623-35. PubMed ID: 17181146
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Design, synthesis and anti-HBV activity of L-amino acid ester prodrugs of acyclic nucleoside phosphonates].
    Fu XZ; Jiang SH; Yang YS; Ji RY
    Yao Xue Xue Bao; 2008 May; 43(5):495-503. PubMed ID: 18717337
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enhancing Oral Bioavailability of Cyclic RGD Hexa-peptides by the Lipophilic Prodrug Charge Masking Approach: Redirection of Peptide Intestinal Permeability from a Paracellular to Transcellular Pathway.
    Schumacher-Klinger A; Fanous J; Merzbach S; Weinmüller M; Reichart F; Räder AFB; Gitlin-Domagalska A; Gilon C; Kessler H; Hoffman A
    Mol Pharm; 2018 Aug; 15(8):3468-3477. PubMed ID: 29976060
    [TBL] [Abstract][Full Text] [Related]  

  • 18. γ-Non-Symmetrically Dimasked TriPPPro Prodrugs as Potential Antiviral Agents against HIV.
    Zhao C; Jia X; Schols D; Balzarini J; Meier C
    ChemMedChem; 2021 Feb; 16(3):499-512. PubMed ID: 33089929
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mononucleoside phosphorodithiolates as mononucleotide prodrugs.
    Schlienger N; Lefebvre I; Aubertin AM; Peyrottes S; Périgaud C
    Eur J Med Chem; 2022 Jan; 227():113914. PubMed ID: 34695774
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and biological evaluation of phosphorodiamidate prodrugs of antiviral and anticancer nucleosides.
    McGuigan C; Bourdin C; Derudas M; Hamon N; Hinsinger K; Kandil S; Madela K; Meneghesso S; Pertusati F; Serpi M; Slusarczyk M; Chamberlain S; Kolykhalov A; Vernachio J; Vanpouille C; Introini A; Margolis L; Balzarini J
    Eur J Med Chem; 2013; 70():326-40. PubMed ID: 24177359
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.