These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 26882437)

  • 1. Native State Mass Spectrometry, Surface Plasmon Resonance, and X-ray Crystallography Correlate Strongly as a Fragment Screening Combination.
    Woods LA; Dolezal O; Ren B; Ryan JH; Peat TS; Poulsen SA
    J Med Chem; 2016 Mar; 59(5):2192-204. PubMed ID: 26882437
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of a New Zinc Binding Chemotype by Fragment Screening.
    Chrysanthopoulos PK; Mujumdar P; Woods LA; Dolezal O; Ren B; Peat TS; Poulsen SA
    J Med Chem; 2017 Sep; 60(17):7333-7349. PubMed ID: 28817930
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Development of drug discovery screening system by molecular interaction kinetics-mass spectrometry.
    Obi N; Fukuda T; Nakayama N; Ervin J; Bando Y; Nishimura T; Nagatoishi S; Tsumoto K; Kawamura T
    Rapid Commun Mass Spectrom; 2018 Apr; 32(8):665-671. PubMed ID: 29441684
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Proof-of-Concept Fragment Screening of a Hit-Validated 96-Compounds Library against Human Carbonic Anhydrase II.
    Glöckner S; Heine A; Klebe G
    Biomolecules; 2020 Mar; 10(4):. PubMed ID: 32235320
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Kinetic analysis and fragment screening with Fujifilm AP-3000.
    Rich RL; Myszka DG
    Anal Biochem; 2010 Jul; 402(2):170-8. PubMed ID: 20371220
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition profiling of human carbonic anhydrase II by high-throughput screening of structurally diverse, biologically active compounds.
    Iyer R; Barrese AA; Parakh S; Parker CN; Tripp BC
    J Biomol Screen; 2006 Oct; 11(7):782-91. PubMed ID: 16858005
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of carbonic anhydrase II by thioxolone: a mechanistic and structural study.
    Barrese AA; Genis C; Fisher SZ; Orwenyo JN; Kumara MT; Dutta SK; Phillips E; Kiddle JJ; Tu C; Silverman DN; Govindasamy L; Agbandje-McKenna M; McKenna R; Tripp BC
    Biochemistry; 2008 Mar; 47(10):3174-84. PubMed ID: 18266323
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Glitazone Class of Drugs as Carbonic Anhydrase Inhibitors-A Spin-Off Discovery from Fragment Screening.
    Mueller SL; Chrysanthopoulos PK; Halili MA; Hepburn C; Nebl T; Supuran CT; Nocentini A; Peat TS; Poulsen SA
    Molecules; 2021 May; 26(10):. PubMed ID: 34070212
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Combining biophysical screening and X-ray crystallography for fragment-based drug discovery.
    Hennig M; Ruf A; Huber W
    Top Curr Chem; 2012; 317():115-43. PubMed ID: 21837555
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Promiscuity of carbonic anhydrase II. Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors.
    Lopez M; Vu H; Wang CK; Wolf MG; Groenhof G; Innocenti A; Supuran CT; Poulsen SA
    J Am Chem Soc; 2011 Nov; 133(45):18452-62. PubMed ID: 21958118
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Experimental validation of a fragment library for lead discovery using SPR biosensor technology.
    Elinder M; Geitmann M; Gossas T; Källblad P; Winquist J; Nordström H; Hämäläinen M; Danielson UH
    J Biomol Screen; 2011 Jan; 16(1):15-25. PubMed ID: 21149860
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency.
    Pacchiano F; Aggarwal M; Avvaru BS; Robbins AH; Scozzafava A; McKenna R; Supuran CT
    Chem Commun (Camb); 2010 Nov; 46(44):8371-3. PubMed ID: 20922253
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of human carbonic anhydrase isozymes I, II and VI with a series of bisphenol, methoxy and bromophenol compounds.
    Balaydin HT; Durdaği S; Ekinci D; Sentürk M; Göksu S; Menzek A
    J Enzyme Inhib Med Chem; 2012 Aug; 27(4):467-75. PubMed ID: 21815772
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Virtual screening-driven identification of human carbonic anhydrase inhibitors incorporating an original, new pharmacophore.
    Pala N; Dallocchio R; Dessì A; Brancale A; Carta F; Ihm S; Maresca A; Sechi M; Supuran CT
    Bioorg Med Chem Lett; 2011 Apr; 21(8):2515-20. PubMed ID: 21420862
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and evaluation of N-heteroarylsubstituted triazolosulfonamides as carbonic anhydrase inhibitors.
    Balci A; Arslan M; Nixha AR; Bilen C; Ergun A; Gençer N
    J Enzyme Inhib Med Chem; 2015 Jun; 30(3):377-82. PubMed ID: 25068730
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies.
    Carta F; Garaj V; Maresca A; Wagner J; Avvaru BS; Robbins AH; Scozzafava A; McKenna R; Supuran CT
    Bioorg Med Chem; 2011 May; 19(10):3105-19. PubMed ID: 21515057
    [TBL] [Abstract][Full Text] [Related]  

  • 17. From experimental design to validated hits a comprehensive walk-through of fragment lead identification using surface plasmon resonance.
    Giannetti AM
    Methods Enzymol; 2011; 493():169-218. PubMed ID: 21371592
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fragment-based discovery of focal adhesion kinase inhibitors.
    Grädler U; Bomke J; Musil D; Dresing V; Lehmann M; Hölzemann G; Greiner H; Esdar C; Krier M; Heinrich T
    Bioorg Med Chem Lett; 2013 Oct; 23(19):5401-9. PubMed ID: 23973211
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biophysical methods for identifying fragment-based inhibitors of protein-protein interactions.
    Pfaff SJ; Chimenti MS; Kelly MJ; Arkin MR
    Methods Mol Biol; 2015; 1278():587-613. PubMed ID: 25859978
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hsp90 inhibitors and drugs from fragment and virtual screening.
    Roughley S; Wright L; Brough P; Massey A; Hubbard RE
    Top Curr Chem; 2012; 317():61-82. PubMed ID: 21647838
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.