BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

321 related articles for article (PubMed ID: 26886346)

  • 1. Acetate- and Citrate-Specific Ion Effects on Unfolding and Temperature-Dependent Aggregation Rates of Anti-Streptavidin IgG1.
    Barnett GV; Razinkov VI; Kerwin BA; Hillsley A; Roberts CJ
    J Pharm Sci; 2016 Mar; 105(3):1066-73. PubMed ID: 26886346
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Specific-ion effects on the aggregation mechanisms and protein-protein interactions for anti-streptavidin immunoglobulin gamma-1.
    Barnett GV; Razinkov VI; Kerwin BA; Laue TM; Woodka AH; Butler PD; Perevozchikova T; Roberts CJ
    J Phys Chem B; 2015 May; 119(18):5793-804. PubMed ID: 25885209
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effects of temperature and osmolytes on competing degradation routes for an IgG1 antibody.
    Roberts CJ; Nesta DP; Kim N
    J Pharm Sci; 2013 Oct; 102(10):3556-66. PubMed ID: 23873602
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Predicting accelerated aggregation rates for monoclonal antibody formulations, and challenges for low-temperature predictions.
    Brummitt RK; Nesta DP; Roberts CJ
    J Pharm Sci; 2011 Oct; 100(10):4234-43. PubMed ID: 21671226
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effects of Protein Conformation, Apparent Solubility, and Protein-Protein Interactions on the Rates and Mechanisms of Aggregation for an IgG1Monoclonal Antibody.
    Kalonia C; Toprani V; Toth R; Wahome N; Gabel I; Middaugh CR; Volkin DB
    J Phys Chem B; 2016 Jul; 120(29):7062-75. PubMed ID: 27380437
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Relation of Colloidal and Conformational Stabilities to Aggregate Formation in a Monoclonal Antibody.
    Oyama H; Koga H; Tadokoro T; Maenaka K; Shiota A; Yokoyama M; Noda M; Torisu T; Uchiyama S
    J Pharm Sci; 2020 Jan; 109(1):308-315. PubMed ID: 31669120
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Aggregation of anti-streptavidin immunoglobulin gamma-1 involves Fab unfolding and competing growth pathways mediated by pH and salt concentration.
    Kim N; Remmele RL; Liu D; Razinkov VI; Fernandez EJ; Roberts CJ
    Biophys Chem; 2013 Feb; 172():26-36. PubMed ID: 23334430
    [TBL] [Abstract][Full Text] [Related]  

  • 8. High-throughput screening and stability optimization of anti-streptavidin IgG1 and IgG2 formulations.
    Alekseychyk L; Su C; Becker GW; Treuheit MJ; Razinkov VI
    J Biomol Screen; 2014 Oct; 19(9):1290-301. PubMed ID: 25023322
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Excipients differentially influence the conformational stability and pretransition dynamics of two IgG1 monoclonal antibodies.
    Thakkar SV; Joshi SB; Jones ME; Sathish HA; Bishop SM; Volkin DB; Middaugh CR
    J Pharm Sci; 2012 Sep; 101(9):3062-77. PubMed ID: 22581714
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Investigating the Degradation Behaviors of a Therapeutic Monoclonal Antibody Associated with pH and Buffer Species.
    Zheng S; Qiu D; Adams M; Li J; Mantri RV; Gandhi R
    AAPS PharmSciTech; 2017 Jan; 18(1):42-48. PubMed ID: 26340951
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparative effects of pH and ionic strength on protein-protein interactions, unfolding, and aggregation for IgG1 antibodies.
    Sahin E; Grillo AO; Perkins MD; Roberts CJ
    J Pharm Sci; 2010 Dec; 99(12):4830-48. PubMed ID: 20821389
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular Computations of Preferential Interaction Coefficients of IgG1 Monoclonal Antibodies with Sorbitol, Sucrose, and Trehalose and the Impact of These Excipients on Aggregation and Viscosity.
    Cloutier T; Sudrik C; Mody N; Sathish HA; Trout BL
    Mol Pharm; 2019 Aug; 16(8):3657-3664. PubMed ID: 31276620
    [TBL] [Abstract][Full Text] [Related]  

  • 13. High throughput thermostability screening of monoclonal antibody formulations.
    He F; Hogan S; Latypov RF; Narhi LO; Razinkov VI
    J Pharm Sci; 2010 Apr; 99(4):1707-20. PubMed ID: 19780136
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The effect of arginine glutamate on the stability of monoclonal antibodies in solution.
    Kheddo P; Tracka M; Armer J; Dearman RJ; Uddin S; van der Walle CF; Golovanov AP
    Int J Pharm; 2014 Oct; 473(1-2):126-33. PubMed ID: 24992318
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of buffer species on the unfolding and the aggregation of humanized IgG.
    Kameoka D; Masuzaki E; Ueda T; Imoto T
    J Biochem; 2007 Sep; 142(3):383-91. PubMed ID: 17646171
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Understanding the Role of Preferential Exclusion of Sugars and Polyols from Native State IgG1 Monoclonal Antibodies and its Effect on Aggregation and Reversible Self-Association.
    Sudrik CM; Cloutier T; Mody N; Sathish HA; Trout BL
    Pharm Res; 2019 May; 36(8):109. PubMed ID: 31127417
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sorbitol crystallization-induced aggregation in frozen mAb formulations.
    Piedmonte DM; Hair A; Baker P; Brych L; Nagapudi K; Lin H; Cao W; Hershenson S; Ratnaswamy G
    J Pharm Sci; 2015 Feb; 104(2):686-97. PubMed ID: 25219372
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Formulation design and high-throughput excipient selection based on structural integrity and conformational stability of dilute and highly concentrated IgG1 monoclonal antibody solutions.
    Bhambhani A; Kissmann JM; Joshi SB; Volkin DB; Kashi RS; Middaugh CR
    J Pharm Sci; 2012 Mar; 101(3):1120-35. PubMed ID: 22147527
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nano Differential Scanning Fluorimetry-Based Thermal Stability Screening and Optimal Buffer Selection for Immunoglobulin G.
    Kim SH; Yoo HJ; Park EJ; Na DH
    Pharmaceuticals (Basel); 2021 Dec; 15(1):. PubMed ID: 35056086
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nonnative aggregation of an IgG1 antibody in acidic conditions: part 1. Unfolding, colloidal interactions, and formation of high-molecular-weight aggregates.
    Brummitt RK; Nesta DP; Chang L; Chase SF; Laue TM; Roberts CJ
    J Pharm Sci; 2011 Jun; 100(6):2087-103. PubMed ID: 21213308
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.